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D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
56094
World Ranking
4427
National Ranking
2149

Overview

Hans-Peter Gerber is affiliated with Seattle Genetics in the United States. Their research primarily spans the field of Medicine, with a notable focus on Oncology, Immunology, Radiology, Nuclear Medicine and Imaging, Immunology and Allergy, and Hematology as subfields of study.

Their work is concentrated around several main topics, including:

  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • HER2/EGFR in Cancer Research
  • Cancer Immunotherapy and Biomarkers
  • Cell Adhesion Molecules Research
  • Monoclonal and Polyclonal Antibodies Research
  • Lung Cancer Treatments and Mutations

Frequent coauthors with whom Hans-Peter Gerber has collaborated are:

  • Christopher J. O'Donnell
  • Krishna Bajjuri
  • Cuong Tran
  • Gang Yin
  • Alice Yam

The scientist has published multiple papers across several venues. Frequent publication venues include:

  • Molecular Cancer Therapeutics
  • Cancer Research
  • Cell Reports Medicine
  • mAbs
  • Clinical Cancer Research

Recent papers authored or coauthored by Hans-Peter Gerber include:

  • "PF-06804103, A Site-specific Anti-HER2 Antibody-Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers" (2020) in Molecular Cancer Therapeutics
  • "NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells" (2021) in Cell Reports Medicine
  • "Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade" (2022) in Molecular Cancer Therapeutics
  • "Therapeutic index improvement of antibody-drug conjugates" (2023) in mAbs
  • "Development of Highly Optimized Antibody-Drug Conjugates against CD33 and CD123 for Acute Myeloid Leukemia" (2020) in Clinical Cancer Research

Best Publications

  • The biology of VEGF and its receptors.

    Napoleone Ferrara;Hans-Peter Gerber;Jennifer LeCouter

  • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

    Napoleone Ferrara;Kenneth J. Hillan;Hans-Peter Gerber;William Novotny

  • Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway REQUIREMENT FOR Flk-1/KDR ACTIVATION

    Hans Peter Gerber;Amy McMurtrey;Joe Kowalski;Minhong Yan

  • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation.

    Hans-Peter Gerber;Thiennu H. Vu;Anne M. Ryan;Joe Kowalski

  • HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation

    Thorsten Cramer;Yuji Yamanishi;Björn E Clausen;Irmgard Förster

  • VEGF inhibition and renal thrombotic microangiopathy.

    Vera Eremina;J. Ashley Jefferson;Jolanta Kowalewska;Howard Hochster

  • Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

    Vera Eremina;Manish Sood;Jody Haigh;András Nagy

  • Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells

    Hans-Peter Gerber;Vishva Dixit;Napoleone Ferrara

  • VEGF is required for growth and survival in neonatal mice

    Hans-Peter Gerber;Kenneth J. Hillan;Anne M. Ryan;Joe Kowalski

  • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes : Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia

    Hans-Peter Gerber;Fabrizio Condorelli;Jeanie Park;Napoleone Ferrara

  • Arterial Thromboembolic Events in Patients with Metastatic Carcinoma Treated with Chemotherapy and Bevacizumab

    Frank A. Scappaticci;Jamey R. Skillings;Scott N. Holden;Hans Peter Gerber

  • Tumor refractoriness to anti-VEGF treatment is mediated by CD11b + Gr1 + myeloid cells

    Farbod Shojaei;Xiumin Wu;Ajay K Malik;Cuiling Zhong

  • VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

    Hans-Peter Gerber;Ajay K. Malik;Gregg P. Solar;Daniel Sherman

  • Vascular endothelial growth factor is essential for corpus luteum angiogenesis

    Napoleone Ferrara;Helen Chen;Terri Davis-Smyth;Hans-Peter Gerber

  • Corneal avascularity is due to soluble VEGF receptor-1

    Balamurali K. Ambati;Miho Nozaki;Nirbhai Singh;Atsunobu Takeda

  • Vascular Endothelial Growth Factor Molecular and Biological Aspects

    Napoleone Ferrara;Hans Peter Gerber

  • Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.

    Jennifer LeCouter;Dirk R. Moritz;Bing Li;Gail Lewis Phillips

  • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies.

    Hans-Peter Gerber;Napoleone Ferrara

  • Transcriptional activation modulated by homopolymeric glutamine and proline stretches.

    Hans-Peter Gerber;Katja Seipel;Oleg Georgiev;Manuela Höfferer

  • The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.

    Ganka Nikolova;Normund Jabs;Irena Konstantinova;Anna Domogatskaya

Frequent Co-Authors

Napoleone Ferrara
Napoleone Ferrara University of California, San Diego
Germaine Fuh
Germaine Fuh Genentech
Audrey Goddard
Audrey Goddard Gilead Sciences
Dan L. Eaton
Dan L. Eaton Genentech
Wei-Qiang Gao
Wei-Qiang Gao Shanghai Jiao Tong University
Christian Wiesmann
Christian Wiesmann Novartis (Switzerland)
Sachdev S. Sidhu
Sachdev S. Sidhu University of Waterloo

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