Masabumi Shibuya

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award
• 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

  J Waltenberger;L Claesson-Welsh;A Siegbahn;M Shibuya

  2216
  Citations

• Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.

  Masabumi Shibuya;Sachiko Yamaguchi;Akira Yamane;Toshio Ikeda

  1666
  Citations

• Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

  Sachie Hiratsuka;Osamu Minowa;Junko Kuno;Tetsuo Noda

  1584
  Citations

• Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies

  Masabumi Shibuya

  1563
  Citations

• D-type cyclin-dependent kinase activity in mammalian cells.

  H Matsushime;D E Quelle;S A Shurtleff;M Shibuya

  1409
  Citations

• Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis

  Masabumi Shibuya;Lena Claesson-Welsh

  1350
  Citations

• The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions.

  Hiroyuki Takahashi;Masabumi Shibuya

  1249
  Citations

• MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis.

  Sachie Hiratsuka;Kazuhiro Nakamura;Shinobu Iwai;Masato Murakami

  1245
  Citations

• A single autophosphorylation site on KDR/Flk‐1 is essential for VEGF‐A‐dependent activation of PLC‐γ and DNA synthesis in vascular endothelial cells

  Tomoko Takahashi;Sachiko Yamaguchi;Kazuhiro Chida;Masabumi Shibuya

  1028
  Citations

• Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

  Monica Autiero;Johannes Waltenberger;Didier Communi;Andrea Kranz

  1015
  Citations

• Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

  Tuomas Tammela;Georgia Zarkada;Elisabet Wallgard;Aino Murtomäki

  962
  Citations

• Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases.

  Masabumi Shibuya

  877
  Citations

• Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis.

  Masabumi Shibuya

  854
  Citations

• Corneal avascularity is due to soluble VEGF receptor-1

  Balamurali K. Ambati;Miho Nozaki;Nirbhai Singh;Atsunobu Takeda

  844
  Citations

• VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

  Tomoko Takahashi;Hikaru Ueno;Masabumi Shibuya

  816
  Citations

• The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

  Sachie Hiratsuka;Akira Watanabe;Yoshiko Sakurai;Sachiko Akashi-Takamura

  797
  Citations

• Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells.

  Birgitta Olofsson;Eija Korpelainen;Michael S. Pepper;Stefano J. Mandriota

  736
  Citations

• Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans

  Asako Sawano;Shinobu Iwai;Yoshiko Sakurai;Mikito Ito

  718
  Citations

• Structure and Function of VEGF/VEGF-receptor System Involved in Angiogenesis

  Masabumi Shibuya

  700
  Citations

• A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF.

  L Seetharam;N Gotoh;Y Maru;G Neufeld

  636
  Citations