D-Index & Metrics Best Publications
Masabumi Shibuya

Masabumi Shibuya

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 90 Citations 39,805 269 World Ranking 1054 National Ranking 60
Medicine D-index 86 Citations 26,542 207 World Ranking 7107 National Ranking 156

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Masabumi Shibuya mostly deals with Vascular endothelial growth factor, Vascular endothelial growth factor A, Angiogenesis, Receptor tyrosine kinase and Tyrosine kinase. Masabumi Shibuya is investigating Cancer research and Internal medicine as part of his examination of Vascular endothelial growth factor. The concepts of his Vascular endothelial growth factor A study are interwoven with issues in Blood vessel, Signal transduction and Growth factor.

His research integrates issues of Vasculogenesis, Aniridia, Pathology, Cornea and Fibroblast growth factor in his study of Angiogenesis. The study incorporates disciplines such as Tropomyosin receptor kinase C and Platelet-derived growth factor receptor in addition to Receptor tyrosine kinase. As a part of the same scientific family, Masabumi Shibuya mostly works in the field of Tyrosine kinase, focusing on Endothelial stem cell and, on occasion, Endothelium.

His most cited work include:

  • Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. (1031 citations)
  • D-type cyclin-dependent kinase activity in mammalian cells. (1000 citations)
  • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice (967 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Vascular endothelial growth factor, Cancer research, Angiogenesis, Cell biology and Molecular biology. His Vascular endothelial growth factor research is multidisciplinary, relying on both Endocrinology and Growth factor. His Cancer research research focuses on subjects like Immunology, which are linked to Haematopoiesis and Macrophage.

He works mostly in the field of Angiogenesis, limiting it down to topics relating to Tyrosine kinase and, in certain cases, Tyrosine phosphorylation, as a part of the same area of interest. His Cell biology research includes elements of Embryonic stem cell and Biochemistry. His studies in Molecular biology integrate themes in fields like Cell culture, Protein kinase A and Complementary DNA, Peptide sequence, Gene.

He most often published in these fields:

  • Vascular endothelial growth factor (39.43%)
  • Cancer research (37.85%)
  • Angiogenesis (36.28%)

What were the highlights of his more recent work (between 2008-2016)?

  • Angiogenesis (36.28%)
  • Cancer research (37.85%)
  • Vascular endothelial growth factor (39.43%)

In recent papers he was focusing on the following fields of study:

Angiogenesis, Cancer research, Vascular endothelial growth factor, Internal medicine and Vascular endothelial growth factor A are his primary areas of study. His Angiogenesis study integrates concerns from other disciplines, such as Endothelial stem cell, Lymphangiogenesis, Tyrosine kinase, Receptor and Cell biology. His Cancer research study combines topics in areas such as Hypoxia, Cancer cell, Immunology, Tumor progression and In vivo.

Masabumi Shibuya mostly deals with Vascular endothelial growth inhibitor in his studies of Vascular endothelial growth factor. His study in Internal medicine is interdisciplinary in nature, drawing from both Apoptosis, Endocrinology and Haematopoiesis, Stem cell. His work in the fields of Vascular endothelial growth factor A, such as Vascular endothelial growth factor B and Kinase insert domain receptor, overlaps with other areas such as Postpartum period.

Between 2008 and 2016, his most popular works were:

  • M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis (288 citations)
  • The spatiotemporal development of adipose tissue (118 citations)
  • Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity. (107 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Masabumi Shibuya spends much of his time researching Angiogenesis, Cancer research, Endocrinology, Internal medicine and Vascular endothelial growth factor A. As part of one scientific family, Masabumi Shibuya deals mainly with the area of Angiogenesis, narrowing it down to issues related to the Vascular endothelial growth factor B, and often Combination therapy, Receptor, Central nervous system, Vascular endothelial growth factor C and Neuropilin 1. Masabumi Shibuya is studying Vascular endothelial growth factor, which is a component of Cancer research.

His studies deal with areas such as Tyrosine kinase and Mesenchymal stem cell, Cell biology as well as Endocrinology. His study in the fields of Adipocyte, 3T3-L1 and Transient receptor potential channel under the domain of Internal medicine overlaps with other disciplines such as Adipose tissue macrophages. Masabumi Shibuya combines subjects such as Cancer cell, Growth factor and Vascular permeability with his study of Vascular endothelial growth factor A.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.

Masabumi Shibuya;Sachiko Yamaguchi;Akira Yamane;Toshio Ikeda.
Oncogene (1990)

1624 Citations

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

Sachie Hiratsuka;Osamu Minowa;Junko Kuno;Tetsuo Noda.
Proceedings of the National Academy of Sciences of the United States of America (1998)

1530 Citations

D-type cyclin-dependent kinase activity in mammalian cells.

H Matsushime;D E Quelle;S A Shurtleff;M Shibuya.
Molecular and Cellular Biology (1994)

1338 Citations

Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis

Masabumi Shibuya;Lena Claesson-Welsh.
Experimental Cell Research (2006)

1213 Citations

MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis.

Sachie Hiratsuka;Kazuhiro Nakamura;Shinobu Iwai;Masato Murakami.
Cancer Cell (2002)

1112 Citations

The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions.

Hiroyuki Takahashi;Masabumi Shibuya.
Clinical Science (2005)

1040 Citations

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

Monica Autiero;Johannes Waltenberger;Didier Communi;Andrea Kranz.
Nature Medicine (2003)

924 Citations

A single autophosphorylation site on KDR/Flk‐1 is essential for VEGF‐A‐dependent activation of PLC‐γ and DNA synthesis in vascular endothelial cells

Tomoko Takahashi;Sachiko Yamaguchi;Kazuhiro Chida;Masabumi Shibuya.
The EMBO Journal (2001)

918 Citations

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

Tuomas Tammela;Georgia Zarkada;Elisabet Wallgard;Aino Murtomäki.
Nature (2008)

845 Citations

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

Tomoko Takahashi;Hikaru Ueno;Masabumi Shibuya.
Oncogene (1999)

774 Citations

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