Masabumi Shibuya mostly deals with Vascular endothelial growth factor, Vascular endothelial growth factor A, Angiogenesis, Receptor tyrosine kinase and Tyrosine kinase. Masabumi Shibuya is investigating Cancer research and Internal medicine as part of his examination of Vascular endothelial growth factor. The concepts of his Vascular endothelial growth factor A study are interwoven with issues in Blood vessel, Signal transduction and Growth factor.
His research integrates issues of Vasculogenesis, Aniridia, Pathology, Cornea and Fibroblast growth factor in his study of Angiogenesis. The study incorporates disciplines such as Tropomyosin receptor kinase C and Platelet-derived growth factor receptor in addition to Receptor tyrosine kinase. As a part of the same scientific family, Masabumi Shibuya mostly works in the field of Tyrosine kinase, focusing on Endothelial stem cell and, on occasion, Endothelium.
His primary areas of investigation include Vascular endothelial growth factor, Cancer research, Angiogenesis, Cell biology and Molecular biology. His Vascular endothelial growth factor research is multidisciplinary, relying on both Endocrinology and Growth factor. His Cancer research research focuses on subjects like Immunology, which are linked to Haematopoiesis and Macrophage.
He works mostly in the field of Angiogenesis, limiting it down to topics relating to Tyrosine kinase and, in certain cases, Tyrosine phosphorylation, as a part of the same area of interest. His Cell biology research includes elements of Embryonic stem cell and Biochemistry. His studies in Molecular biology integrate themes in fields like Cell culture, Protein kinase A and Complementary DNA, Peptide sequence, Gene.
Angiogenesis, Cancer research, Vascular endothelial growth factor, Internal medicine and Vascular endothelial growth factor A are his primary areas of study. His Angiogenesis study integrates concerns from other disciplines, such as Endothelial stem cell, Lymphangiogenesis, Tyrosine kinase, Receptor and Cell biology. His Cancer research study combines topics in areas such as Hypoxia, Cancer cell, Immunology, Tumor progression and In vivo.
Masabumi Shibuya mostly deals with Vascular endothelial growth inhibitor in his studies of Vascular endothelial growth factor. His study in Internal medicine is interdisciplinary in nature, drawing from both Apoptosis, Endocrinology and Haematopoiesis, Stem cell. His work in the fields of Vascular endothelial growth factor A, such as Vascular endothelial growth factor B and Kinase insert domain receptor, overlaps with other areas such as Postpartum period.
Masabumi Shibuya spends much of his time researching Angiogenesis, Cancer research, Endocrinology, Internal medicine and Vascular endothelial growth factor A. As part of one scientific family, Masabumi Shibuya deals mainly with the area of Angiogenesis, narrowing it down to issues related to the Vascular endothelial growth factor B, and often Combination therapy, Receptor, Central nervous system, Vascular endothelial growth factor C and Neuropilin 1. Masabumi Shibuya is studying Vascular endothelial growth factor, which is a component of Cancer research.
His studies deal with areas such as Tyrosine kinase and Mesenchymal stem cell, Cell biology as well as Endocrinology. His study in the fields of Adipocyte, 3T3-L1 and Transient receptor potential channel under the domain of Internal medicine overlaps with other disciplines such as Adipose tissue macrophages. Masabumi Shibuya combines subjects such as Cancer cell, Growth factor and Vascular permeability with his study of Vascular endothelial growth factor A.
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Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.
Masabumi Shibuya;Sachiko Yamaguchi;Akira Yamane;Toshio Ikeda.
Oncogene (1990)
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
Sachie Hiratsuka;Osamu Minowa;Junko Kuno;Tetsuo Noda.
Proceedings of the National Academy of Sciences of the United States of America (1998)
D-type cyclin-dependent kinase activity in mammalian cells.
H Matsushime;D E Quelle;S A Shurtleff;M Shibuya.
Molecular and Cellular Biology (1994)
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
Masabumi Shibuya;Lena Claesson-Welsh.
Experimental Cell Research (2006)
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis.
Sachie Hiratsuka;Kazuhiro Nakamura;Shinobu Iwai;Masato Murakami.
Cancer Cell (2002)
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions.
Hiroyuki Takahashi;Masabumi Shibuya.
Clinical Science (2005)
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
Monica Autiero;Johannes Waltenberger;Didier Communi;Andrea Kranz.
Nature Medicine (2003)
A single autophosphorylation site on KDR/Flk‐1 is essential for VEGF‐A‐dependent activation of PLC‐γ and DNA synthesis in vascular endothelial cells
Tomoko Takahashi;Sachiko Yamaguchi;Kazuhiro Chida;Masabumi Shibuya.
The EMBO Journal (2001)
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
Tuomas Tammela;Georgia Zarkada;Elisabet Wallgard;Aino Murtomäki.
Nature (2008)
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
Tomoko Takahashi;Hikaru Ueno;Masabumi Shibuya.
Oncogene (1999)
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