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Biology and Biochemistry

D-Index
73
Citations
24734
World Ranking
5838
National Ranking
2763

Research.com Recognitions

  • 1990 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Joseph Bryan is affiliated with the Pacific Northwest Diabetes Research Institute in the United States. Their primary field of study is medicine, with research spanning molecular biology, surgery, physiology, neurology, and cellular and molecular neuroscience. Their work often intersects multiple disciplines related to human health and biological processes.

The scientist has contributed to topics such as:

  • Ion Transport and Channel Regulation
  • Hydrogen's biological and therapeutic effects
  • Ion channel regulation and function
  • Pain Mechanisms and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Nerve injury and regeneration
  • 3D Printing in Biomedical Research

Joseph Bryan's recent publications include the following papers:

  • "Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke" (2023), published in Science Signaling
  • "SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury" (2021), published in Molecular Pain
  • "Engineered Decellularized Matrix Hydrogels with Crypt-Villus Topography for Forming Functional Intestinal Epithelium" (2025), published in Small
  • "Photodegradable Hydrogels Formed by Thiol-Norbornene Photopolymerization of Poly(ethylene glycol)-Norbornene-Carboxylate" (2025), published in ACS Applied Polymer Materials
  • "Microwave-Assisted Aqueous Synthesis of Gelatin-Norbornene for Hydrogel Crosslinking and Bioprinting" (2025), published in Advanced Materials Technologies

The frequent venues of publication for Bryan include:

  • Science Signaling
  • Molecular Pain
  • Small
  • ACS Applied Polymer Materials
  • Advanced Materials Technologies

Frequent collaborators in their research include:

  • Orest Tsymbalyuk
  • Svetlana Ivanova
  • Volodymyr Gerzanich
  • J. Marc Simard
  • Chien-Chi Lin

Joseph Bryan was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 1990. This recognition is part of their professional record in the context of their scientific contributions.

Best Publications

  • Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.

    Nobuya Inagaki;Tohru Gonoi;John P. Clement;Noriyuki Namba

  • Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion.

    Lydia Aguilar-Bryan;Colin G. Nichols;Sérgio W. Wechsler;John P. Clement

  • A Family of Sulfonylurea Receptors Determines the Pharmacological Properties of ATP-Sensitive K+ Channels

    Nobuya Inagaki;Tohru Gonoi;John P. Clement;Chang Zheng Wang

  • Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy

    Pamela M. Thomas;Gilbert J. Cote;Nelson Wohllk;Bassem Haddad

  • Molecular biology of adenosine triphosphate-sensitive potassium channels.

    Lydia Aguilar-Bryan;Joseph Bryan

  • Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.

    Y Ohta;Y Tanizawa;H Inoue;T Hosaka

  • Association and Stoichiometry of KATP Channel Subunits

    John P. Clement;Kumud Kunjilwar;Gabriela Gonzalez;Mathias Schwanstecher

  • Activating Mutations in the ABCC8 Gene in Neonatal Diabetes Mellitus

    Andrey P. Babenko;Michel Polak;Hélène Cavé;Kanetee Busiah

  • Hypothalamic K ATP channels control hepatic glucose production

    Alessandro Pocai;Tony K. T. Lam;Roger Gutierrez-Juarez;Silvana Obici

  • Toward Understanding the Assembly and Structure of KATP Channels

    Lydia Aguilar-Bryan;John P. Clement;Gabriela Gonzalez;Kumud Kunjilwar

  • A VIEW OF SUR/KIR6.X, KATP CHANNELS

    A. P. Babenko;L. Aguilar-Bryan;J. Bryan

  • Microtubules: evidence for 13 protofilaments.

    Lewis G. Tilney;Joseph Bryan;Doris J. Bush;Keigi Fujiwara

  • Adenosine diphosphate as an intracellular regulator of insulin secretion

    Colin Nichols;S. L. Shyng;A. Nestorowicz;B. Glaser

  • Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion.

    Victor Seghers;Mitsuhiro Nakazaki;Franco DeMayo;Lydia Aguilar-Bryan

  • Definition of three classes of binding sites in isolated microtubule crystals.

    Joseph Bryan

  • Are cytoplasmic microtubules heteropolymers

    Joseph Bryan;Leslie Wilson

  • Ns and Ni, the stimulatory and inhibitory regulatory components of adenylyl cyclases. Purification of the human erythrocyte proteins without the use of activating regulatory ligands.

    J Codina;J D Hildebrandt;R D Sekura;M Birnbaumer

  • Neonatal Diabetes Mellitus

    Lydia Aguilar-Bryan;Joseph Bryan

  • Potassium channel openers require ATP to bind to and act through sulfonylurea receptors.

    Mathias Schwanstecher;Claus Sieverding;Henrik Dörschner;Insa Gross

  • Mutations in the Sulfonylurea Receptor Gene Are Associated with Familial Hyperinsulinism in Ashkenazi Jews

    Ann Nestorowicz;Beth Anne Wilson;Kathleen P. Schoor;Hiroshi Inoue

Frequent Co-Authors

Nobuya Inagaki
Nobuya Inagaki Kyoto University
Susumu Seino
Susumu Seino Kobe University
Jorge Ferrer
Jorge Ferrer Imperial College London
Gilbert J. Cote
Gilbert J. Cote The University of Texas MD Anderson Cancer Center
Philippe A. Halban
Philippe A. Halban University of Geneva
John Kendrick-Jones
John Kendrick-Jones MRC Laboratory of Molecular Biology
Joel F. Habener
Joel F. Habener Harvard University
Claes B. Wollheim
Claes B. Wollheim University of Geneva
Melanie J. Davies
Melanie J. Davies University of Leicester
Philippe Froguel
Philippe Froguel Imperial College London

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