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Biology and Biochemistry

D-Index
66
Citations
16186
World Ranking
8641
National Ranking
667

Overview

Jorge Ferrer is affiliated with Imperial College London in the United Kingdom, where their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine. Their scholarly output covers a broad spectrum from molecular biology to surgery, genetics, cancer research, and oncology.

Their recent papers include:

  • Transcription regulation by long non-coding RNAs: mechanisms and disease relevance (2024), published in Nature Reviews Molecular Cell Biology
  • SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation (2020), Signal Transduction and Targeted Therapy
  • The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits (2023), Cell Metabolism
  • TIGER: The gene expression regulatory variation landscape of human pancreatic islets (2021), Cell Reports
  • Current challenges in understanding the role of enhancers in disease (2022), Nature Structural & Molecular Biology

Ferrer's frequent co-authors include Javier García-Hurtado, M.A. Maestro, Sílvia Bonàs-Guarch, Goutham Atla, and Irene Miguel-Escalada. This network of collaborators reflects active engagement across their research domains.

They have published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), with 9 publications; HPB, with 4; Cell Metabolism and Cell Reports, each with 2 publications; and Nature Communications, with 2 publications as well.

Their main fields of study encompass:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad fields, their subfields of study include:

  • Molecular Biology
  • Surgery
  • Genetics
  • Cancer Research
  • Oncology

The primary research topics explored in their work are:

  • Pancreatic function and diabetes
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Genetic Associations and Epidemiology
  • Genetics and Neurodevelopmental Disorders
  • Pancreatic and Hepatic Oncology Research
  • Cancer-related molecular mechanisms research

Best Publications

  • Early-onset type-II diabetes mellitus (MODY4) linked to IPF1.

    D A Stoffers;J Ferrer;J Ferrer;W L Clarke;J F Habener

  • A map of open chromatin in human pancreatic islets

    Kyle J. Gaulton;Takao Nammo;Lorenzo Pasquali;Jeremy M. Simon

  • Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

    Myriam Solar;Carina Cardalda;Isabelle Houbracken;Isabelle Houbracken;Mercè Martín

  • Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

    Lorenzo Pasquali;Kyle J Gaulton;Kyle J Gaulton;Kyle J Gaulton;Santiago A Rodríguez-Seguí;Loris Mularoni

  • Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene

    Ewan R Pearson;Sylvia F Boj;Anna M Steele;Timothy Barrett

  • Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

    Natalie R. Johnston;Ryan K. Mitchell;Elizabeth Haythorne;Maria Paiva Pessoa

  • Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes

    Ignasi Morán;İldem Akerman;Martijn van de Bunt;Martijn van de Bunt;Ruiyu Xie

  • Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

    Kyle J Gaulton;Kyle J Gaulton;Teresa Ferreira;Yeji Lee;Anne Raimondo

  • GATA6 haploinsufficiency causes pancreatic agenesis in humans

    Hana Lango Allen;Sarah E Flanagan;Charles Shaw-Smith;Elisa De Franco

  • A transcription factor regulatory circuit in differentiated pancreatic cells

    Sylvia F. Boj;Marcelina Párrizas;Miguel A. Maestro;Jorge Ferrer

  • Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis

    Michael N Weedon;Inês Cebola;Ann-Marie Patch;Sarah E Flanagan

  • Measuring molecular rupture forces between single actin filaments and actin-binding proteins

    Jorge M. Ferrer;Hyungsuk Lee;Jiong Chen;Benjamin Pelz;Benjamin Pelz

  • Ins1(Cre) knock-in mice for beta cell-specific gene recombination.

    Bernard Thorens;David Tarussio;Miguel Angel Maestro;Meritxell Rovira

  • Transcriptional networks controlling pancreatic development and beta cell function

    J. M. Servitja;J. Ferrer

  • Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

    Irene Miguel-Escalada;Silvia Bonàs-Guarch;Inês Cebola;Joan Ponsa-Cobas

  • TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors

    Inês Cebola;Santiago A. Rodríguez-Seguí;Candy H.-H. Cho;José Bessa;José Bessa

  • Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks

    Ildem Akerman;Ildem Akerman;Zhidong Tu;Anthony Beucher;Delphine M Y Rolando

  • Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.

    Keith Al-Hasani;Anja Pfeifer;Anja Pfeifer;Anja Pfeifer;Monica Courtney;Monica Courtney;Monica Courtney;Nouha Ben-Othman;Nouha Ben-Othman;Nouha Ben-Othman

  • The miRNA Profile of Human Pancreatic Islets and Beta-Cells and Relationship to Type 2 Diabetes Pathogenesis

    Martijn van de Bunt;Martijn van de Bunt;Kyle J. Gaulton;Leopold Parts;Ignasi Moran

  • IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

    Georg Mellitzer;Stefan Bonné;Reini F Luco;Mark Van De Casteele

Frequent Co-Authors

Miguel A. Maestro
Miguel A. Maestro University of A Coruña
Josep M. Mercader
Josep M. Mercader Broad Institute
Anna L. Gloyn
Anna L. Gloyn Stanford University
Torben Hansen
Torben Hansen University of Copenhagen
Philippe Ravassard
Philippe Ravassard Université Paris Cité
Lorenzo Piemonti
Lorenzo Piemonti Vita-Salute San Raffaele University
David Torrents
David Torrents Barcelona Supercomputing Center
Oluf Pedersen
Oluf Pedersen University of Copenhagen
Allan Linneberg
Allan Linneberg University of Copenhagen

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