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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
9663
World Ranking
14029
National Ranking
5918

Overview

Jaime F. Modiano is affiliated with the University of Minnesota in the United States. Their research integrates multiple disciplines, primarily in Biochemistry, Genetics and Molecular Biology, and Medicine. Their expertise spans subfields such as Pulmonary and Respiratory Medicine, Molecular Biology, Cancer Research, Genetics, and Oncology.

The scientist's work covers main topics including Veterinary Oncology Research, Virus-based gene therapy research, Sarcoma Diagnosis and Treatment, Cancer Genomics and Diagnostics, Cancer-related molecular mechanisms research, Cancer Research and Treatments, and Extracellular vesicles in disease.

Frequent collaborators of Jaime F. Modiano include Aaron L. Sarver, Kelly M. Makielski, Ashley J. Schulte, Sara Pracht, and Antonella Borgatti.

Their notable recent publications include:

  • Isolation of Cancer-Derived Exosomes Using a Variety of Magnetic Nanostructures: From Fe3O4 Nanoparticles to Ni Nanowires (2020, Nanomaterials)
  • Increased risk of cancer in dogs and humans: A consequence of recent extension of lifespan beyond evolutionarily determined limitations? (2022, Aging and Cancer)
  • Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions (2021, Molecular Cancer Research)
  • Retrospective evaluation of thrombocytopenia and tumor stage as prognostic indicators in dogs with splenic hemangiosarcoma (2021, Journal of the American Veterinary Medical Association)
  • Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer (2020, PLoS ONE)

Jaime F. Modiano frequently publishes in venues such as Cancer Research, UNC Libraries, Clinical Cancer Research, Journal of Clinical Oncology, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Rethinking dog domestication by integrating genetics, archeology, and biogeography

    Greger Larson;Elinor K. Karlsson;Angela Perri;Matthew T. Webster

  • The dog as a cancer model.

    Chand Khanna;Kerstin Lindblad-Toh;David Vail;Cheryl London

  • Diagnosis of Canine Lymphoid Neoplasia Using Clonal Rearrangements of Antigen Receptor Genes

    R. C. Burnett;William Vernau;J. F. Modiano;J. F. Modiano;C. S. Olver

  • Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans – man and his best friend share more than companionship

    Matthew Breen;Jaime F. Modiano;Jaime F. Modiano

  • A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

    Branden S Moriarity;George M Otto;Eric P Rahrmann;Susan K Rathe

  • Distinct B-Cell and T-Cell Lymphoproliferative Disease Prevalence among Dog Breeds Indicates Heritable Risk

    Jaime F. Modiano;Matthew Breen;Robert C. Burnett;Heidi G. Parker

  • NFATc2-mediated repression of cyclin-dependent kinase 4 expression.

    Shairaz Baksh;Hans R. Widlund;Ashley A. Frazer-Abel;Jinyan Du

  • Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression

    Jamin A. Willoughby;Shyam N. Sundar;Mark Cheung;Antony S. Tin

  • Canine lymphoma as a comparative model for human non-Hodgkin lymphoma: recent progress and applications.

    Daisuke Ito;Aric M. Frantz;Jaime F. Modiano

  • Isolation of Cancer-Derived Exosomes Using a Variety of Magnetic Nanostructures: From Fe3O4 Nanoparticles to Ni Nanowires.

    Zohreh Nemati;Mohammad Reza Zamani Kouhpanji;Fang Zhou;Raja Das

  • Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

    Elinor K Karlsson;Elinor K Karlsson;Snaevar Sigurdsson;Snaevar Sigurdsson;Emma Ivansson;Emma Ivansson;Rachael Thomas

  • Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation.

    Angela R. Lamerato-Kozicki;Karen M. Helm;Cristan M. Jubala;Gary C. Cutter

  • Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma

    Venugopal Thayanithy;Aaron L. Sarver;Reena V. Kartha;Lihua Li

  • Expression and Significance of p53, Rb, p21/waf-1, p16/ink-4a, and PTEN Tumor Suppressors in Canine Melanoma

    A. Koenig;S. R. Bianco;S. Fosmire;J. Wojcieszyn

  • CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma.

    C. M. Jubala;J. W. Wojcieszyn;V. E. O. Valli;D. M. Getzy

  • Molecular Profiling Reveals Prognostically Significant Subtypes of Canine Lymphoma

    A. M. Frantz;Aaron L Sarver;D. Ito;T. L. Phang;T. L. Phang

  • Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

    Milcah C. Scott;Aaron L. Sarver;Katherine J. Gavin;Venugopal Thayanithy

  • Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma

    Beth A Tamburini;Tzu L Phang;Susan P Fosmire;Milcah C Scott

  • Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

    Ingegerd Elvers;Jason Turner-Maier;Ross Swofford;Michele Koltookian

  • Gene Expression Profiles of Sporadic Canine Hemangiosarcoma Are Uniquely Associated with Breed

    Beth A. Tamburini;Susan Trapp;Tzu Lip Phang;Jill T. Schappa

Frequent Co-Authors

Matthew Breen
Matthew Breen North Carolina State University
Kerstin Lindblad-Toh
Kerstin Lindblad-Toh Uppsala University
Timothy O'Brien
Timothy O'Brien University of Minnesota
Elinor K. Karlsson
Elinor K. Karlsson Broad Institute
Subbaya Subramanian
Subbaya Subramanian University of Minnesota
Gary Cutter
Gary Cutter University of Alabama at Birmingham
Cheryl A. London
Cheryl A. London Tufts University
Daniel A. Vallera
Daniel A. Vallera University of Minnesota
David A. Largaespada
David A. Largaespada University of Minnesota
William J. Murphy
William J. Murphy Texas A&M University

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