World's Best Scientists 2026 revealed!

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Medicine

D-Index
118
Citations
47265
World Ranking
4078
National Ranking
398

Research.com Recognitions

  • 2018 - Nordic Medical Prize, SalusAnsvar/Ulf Nilsonnes Foundation for Medical Research
  • 2014 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Patrik Rorsman is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on the molecular and physiological aspects of pancreatic function and diabetes, contributing extensively to the fields of medicine and biochemistry, genetics, and molecular biology.

The scientist has published widely on topics related to pancreatic function and diabetes, diabetes management and research, diabetes and associated disorders, diabetes treatment and management, metabolism related to diabetes and cancer, lipid membrane structure and behavior, and adipose tissue and metabolism.

Key recent papers include:

  • A method for the generation of human stem cell-derived alpha cells, 2020, Nature Communications
  • Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes, 2020, Journal of Clinical Investigation
  • A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells, 2022, Nature Communications
  • Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells, 2022, Nature Communications
  • Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state, 2022, Cell Metabolism

They have collaborated frequently with several co-authors, including Haiqiang Dou, Quan Zhang, Andrei I. Tarasov, Thomas G. Hill, and Johan Tolö.

Patrik Rorsman has contributed to scientific knowledge published mainly in leading journals such as Diabetes, Nature Metabolism, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, and Molecular Metabolism.

Their work spans multiple subfields including surgery, endocrinology, diabetes and metabolism, molecular biology, genetics, and physiology.

Notable awards received include the Nordic Medical Prize from SalusAnsvar/Ulf Nilsonnes Foundation for Medical Research in 2018, election as a Fellow of the Royal Society in the United Kingdom in 2014, and fellowship of The Academy of Medical Sciences in the United Kingdom.

Best Publications

  • A pancreatic islet-specific microRNA regulates insulin secretion

    Matthew N. Poy;Lena Eliasson;Jan Krutzfeldt;Satoru Kuwajima

  • The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate–Dependent Nucleic Acid Demethylase

    Thomas Gerken;Christophe A. Girard;Yi-Chun Loraine Tung;Celia J. Webby

  • Electrophysiology of the pancreatic beta-cell.

    Frances M. Ashcroft;Patrik Rorsman

  • Diabetes Mellitus and the β Cell: The Last Ten Years

    Frances M. Ashcroft;Patrik Rorsman;Patrik Rorsman

  • Insulin granule dynamics in pancreatic beta cells

    Patrik Rorsman;Patrik Rorsman;Erik Renström

  • miR-375 maintains normal pancreatic α- and β-cell mass

    Matthew N. Poy;Jean Hausser;Mirko Trajkovski;Matthias Braun

  • Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men

    Patrik Rorsman;Patrik Rorsman;Frances M. Ashcroft;Frances M. Ashcroft

  • Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells.

    G Trube;P Rorsman;T Ohno-Shosaku

  • Regulation of Insulin Secretion in Human Pancreatic Islets

    Patrik Rorsman;Matthias Braun

  • Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.

    Patrik Rorsman;Per Olof Berggren;Krister Bokvist;Hans Ericson

  • Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion.

    Matthias Braun;Reshma Ramracheya;Martin Bengtsson;Quan Zhang

  • The Cell Physiology of Biphasic Insulin Secretion

    Patrik Rorsman;Lena Eliasson;Erik Renström;Jesper Gromada

  • Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels

    Martin Bengtsson;Anders Ståhlberg;Patrik Rorsman;Mikael Kubista

  • Glucose dependent K+-channels in pancreaticβ-cells are regulated by intracellular ATP

    P. Rorsman;G. Trube

  • Calcium-independent potentiation of insulin release by cyclic AMP in single beta-cells.

    Carina Ämmälä;Frances M. Ashcroft;Patrik Rorsman

  • Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes.

    Jannie Fuhlendorff;Patrik Rorsman;Hans Kofod;Christian L. Brand

  • Calcium and delayed potassium currents in mouse pancreatic beta‐cells under voltage‐clamp conditions.

    P Rorsman;G Trube

  • Glucose-sensing mechanisms in pancreatic beta-cells

    Patrick E MacDonald;Jamie W Joseph;Patrik Rorsman;Patrik Rorsman

  • Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

    Erik Renström;Lena Eliasson;Patrik Rorsman

  • Deletion of the G Protein-Coupled Receptor 30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-Stimulated Insulin Release in Female Mice

    Ulrika E A Mårtensson;S Albert Salehi;Sara H Windahl;Maria F Gomez

Frequent Co-Authors

Lena Eliasson
Lena Eliasson Lund University
Erik Renström
Erik Renström Lund University
Frances M. Ashcroft
Frances M. Ashcroft University of Oxford
Per-Olof Berggren
Per-Olof Berggren Karolinska Institute
Anna L. Gloyn
Anna L. Gloyn Stanford University
Karsten Buschard
Karsten Buschard Copenhagen University Hospital
Frank Reimann
Frank Reimann University of Cambridge
Leif Groop
Leif Groop Lund University
Jesper Gromada
Jesper Gromada Regeneron (United States)

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