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Biology and Biochemistry

D-Index
62
Citations
11619
World Ranking
10966
National Ranking
120

Overview

Karsten Buschard is a researcher affiliated with Copenhagen University Hospital in Denmark, specializing in medical and biochemical research related primarily to diabetes and associated disorders. Their work spans multiple interconnected disciplines, including Medicine and Biochemistry, Genetics and Molecular Biology.

Buschard's research interests focus notably on diabetes, covering both clinical and molecular aspects. Specific topics explored in their publications include:

  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • Diabetes management and research
  • Gut microbiota and health
  • Immune cell function and interaction
  • Metabolism, diabetes, and cancer
  • Liver disease diagnosis and treatment

Their contributions are primarily documented through articles published in peer-reviewed journals. Among recent papers are:

  • Intestinal permeability in type 1 diabetes: An updated comprehensive overview (2021), Journal of Autoimmunity
  • PPARs and the Development of Type 1 Diabetes (2020), PPAR Research
  • Antibiotic treatment during early childhood and risk of type 1 diabetes in children: A national birth cohort study (2020), Pediatric Diabetes
  • Genetic predisposition in the 2'-5'A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity (2021), Diabetologia
  • Gluten-free diet reduces autoimmune diabetes mellitus in mice across multiple generations in a microbiota-independent manner (2022), Journal of Autoimmunity

These publications indicate a strong interest in the immunological and genetic factors of type 1 diabetes, as well as environmental influences such as diet and antibiotic exposure.

Frequent co-authors in Buschard's work include:

  • Martin Haupt-Jorgensen
  • Flemming Pociot
  • Knud Josefsen
  • Lars Krogvold
  • Ivan Gerling

Buschard's research has been disseminated through several publication venues with multiple contributions to journals such as:

  • Apmis
  • PLoS ONE
  • Journal of Autoimmunity
  • Diabetologia
  • Frontiers in Endocrinology

Their scientific output spans various subfields including Genetics, Surgery, Endocrinology, Diabetes and Metabolism, Molecular Biology, and Immunology. The total volume of publications reflects a multidisciplinary approach, bridging fundamental molecular biology with clinical research.

Best Publications

  • Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse

    C H F Hansen;L Krych;D S Nielsen;F K Vogensen

  • Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells.

    Anna Wendt;Bryndis Birnir;Karsten Buschard;Jesper Gromada

  • Reduction of diabetes incidence of BB Wistar rats by early prophylactic insulin treatment of diabetes-prone animals.

    C. F. Gotfredsen;K. Buschard;E. K. Frandsen

  • Gluten-free diet prevents diabetes in NOD mice.

    David P. Funda;Anne Kaas;Troels Bock;Helena Tlaskalová-Hogenová

  • Adrenaline Stimulates Glucagon Secretion in Pancreatic A-Cells by Increasing the Ca2+ Current and the Number of Granules Close to the L-Type Ca2+ Channels

    Jesper Gromada;Krister Bokvist;Wei-Guang Ding;Sebastian Barg

  • Glucose Stimulates Glucagon Release in Single Rat α-Cells by Mechanisms that Mirror the Stimulus-Secretion Coupling in β-Cells

    Hervør Lykke Olsen;Sten Theander;Krister Bokvist;Karsten Buschard

  • A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

    Lea B S Hansen;Henrik M Roager;Henrik M Roager;Nadja B Søndertoft;Rikke J Gøbel

  • Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism

    Wei-Guang Ding;Erik Renström;Patrik Rorsman;Karsten Buschard

  • Characterisation of sulphonylurea and ATP-regulated K+ channels in rat pancreatic A-cells.

    K. Bokvist;H.L. Olsen;M. Høy;C.F. Gotfredsen

  • Glucagon stimulates exocytosis in mouse and rat pancreatic {alpha} cells by binding to glucagon receptors.

    Xiaosong Ma;Yang Zhang;Jesper Gromada;Sabine Sewing

  • Somatostatin inhibits exocytosis in rat pancreatic α-cells by Gi2-dependent activation of calcineurin and depriming of secretory granules

    Jesper Gromada;Marianne Høy;Karsten Buschard;Albert Salehi

  • Differential Expression of Glutamic Acid Decarboxylase in Rat and Human Islets

    Jacob S. Petersen;Steven Russel;Michael O. Marshall;Hans Kofod

  • Prophylactic nutritional modification of the incidence of diabetes in autoimmune non-obese diabetic (NOD) mice

    J Hoorfar;K Buschard;F Dagnaes-Hansen

  • Prevalence and predictive value of islet cell antibodies and insulin autoantibodies in women with gestational diabetes

    P. Damm;C. Kühl;K. Buschard;B. K. Jakobsen

  • Dependence of antigen expression on functional state of β-cells

    Kim Aaen;Jørgen Rygaard;Knud Josefsen;Henrik Petersen

  • Relationship between periodontitis and diabetes: Lessons from rodent studies

    Carla C. Pontes Andersen;Allan Flyvbjerg;Karsten Buschard;Palle Holmstrup

  • Genetic Background Determines the Size and Structure of the Endocrine Pancreas

    Troels Bock;Bente Pakkenberg;Karsten Buschard

  • A Maternal Gluten-Free Diet Reduces Inflammation and Diabetes Incidence in the Offspring of NOD Mice

    Camilla Hartmann Friis Hansen;Lukasz Krych;Karsten Buschard;Stine B. Metzdorff

  • Maternal Age at Birth and Childhood Type 1 Diabetes: A Pooled Analysis of 30 Observational Studies

    Chris R Cardwell;Lars C Stene;Geir Joner;Max K Bulsara

  • Keratin proteins in human oral mucosa.

    H Clausen;D Moe;K Buschard;E Dabelsteen

Frequent Co-Authors

Klaus Bendtzen
Klaus Bendtzen Rigshospitalet
Sten Madsbad
Sten Madsbad University of Copenhagen
Patrik Rorsman
Patrik Rorsman University of Oxford
Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen University of Copenhagen
Bart O. Roep
Bart O. Roep Leiden University Medical Center
Jan-Eric Månsson
Jan-Eric Månsson University of Gothenburg
Bente Pakkenberg
Bente Pakkenberg University of Copenhagen
Dennis S. Nielsen
Dennis S. Nielsen University of Copenhagen
Helena Tlaskalova-Hogenova
Helena Tlaskalova-Hogenova Czech Academy of Sciences
Flemming Pociot
Flemming Pociot Steno Diabetes Center

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