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Helena Tlaskalova-Hogenova

Helena Tlaskalova-Hogenova

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Immunology
Czechia
2026

D-Index & Metrics

Immunology

D-Index
61
Citations
12242
World Ranking
3255
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Immunology in Czechia Leader Award

Overview

Helena Tlaskalova-Hogenova is affiliated with the Czech Academy of Sciences in the Czech Republic. Their research spans several domains within medical and biological sciences, with a primary focus on gut microbiota and its implications for health and disease.

The scientist's research output includes numerous peer-reviewed publications across respected journals. Recent papers include:

  • Gut Microbiota and NAFLD: Pathogenetic Mechanisms, Microbiota Signatures, and Therapeutic Interventions (2021) published in Microorganisms
  • The intestinal microbiota and metabolites in patients with anorexia nervosa (2021) published in Gut Microbes
  • Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling (2020) published in Cells
  • Urinary I-FABP, L-FABP, TFF-3, and SAA Can Diagnose and Predict the Disease Course in Necrotizing Enterocolitis at the Early Stage of Disease (2020) published in Journal of Immunology Research
  • Current Aspects of the Role of Autoantibodies Directed Against Appetite-Regulating Hormones and the Gut Microbiome in Eating Disorders (2021) published in Frontiers in Endocrinology

Frequent co-authors collaborating with Helena Tlaskalova-Hogenova include:

  • Miloslav Kverka
  • Radka Roubalová
  • Štěpán Coufal
  • Jakub Kreisinger
  • Zuzana Jirásková Zákostelská

Publication venues where the scientist has contributed multiple studies encompass:

  • Cells
  • Sleep Medicine
  • Frontiers in Immunology
  • Microorganisms
  • Journal of Immunology Research

Their main fields of study focus on Medicine and Biochemistry, Genetics and Molecular Biology. More specific subfields of research include:

  • Epidemiology
  • Molecular Biology
  • Genetics
  • Physiology
  • Dermatology

Key topics addressed in Helena Tlaskalova-Hogenova's research are:

  • Gut microbiota and health
  • Inflammatory Bowel Disease
  • Eating Disorders and Behaviors
  • Dermatology and Skin Diseases
  • Diet and metabolism studies
  • Microscopic Colitis
  • Infant Nutrition and Health

Best Publications

  • Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases

    Helena Tlaskalová-Hogenová;Renata Stepánková;Tomás Hudcovic;Ludmila Tucková

  • The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases

    Helena Tlaskalová-Hogenová;Renata Štěpánková;Hana Kozáková;Tomáš Hudcovic

  • Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology

    Holm H. Uhlig;Brent S. McKenzie;Sophie Hue;Claire Thompson

  • Nod2 is required for the regulation of commensal microbiota in the intestine

    Tanja Petnicki-Ocwieja;Tomas Hrncir;Yuen-Joyce Liu;Amlan Biswas

  • Oral administration of Parabacteroides distasonis antigens attenuates experimental murine colitis through modulation of immunity and microbiota composition

    M. Kverka;Z. Zakostelska;K. Klimesova;D. Sokol

  • Patterns of early gut colonization shape future immune responses of the host.

    Camilla Hartmann Friis Hansen;Dennis Sandris Nielsen;Miloslav Kverka;Zuzana Zakostelska

  • Gluten-free diet prevents diabetes in NOD mice.

    David P. Funda;Anne Kaas;Troels Bock;Helena Tlaskalová-Hogenová

  • Gut microbiota and lipopolysaccharide content of the diet influence development of regulatory T cells: studies in germ-free mice

    Tomas Hrncir;Renata Stepankova;Hana Kozakova;Tomas Hudcovic

  • Lysate of probiotic Lactobacillus casei DN-114 001 ameliorates colitis by strengthening the gut barrier function and changing the gut microenvironment.

    Zuzana Zakostelska;Miloslav Kverka;Klara Klimesova;Pavel Rossmann

  • Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells

    Renata Stepankova;Fiona Powrie;Olga Kofronova;Hana Kozakova

  • Expression of Toll-like receptor 2 (TLR2), TLR4, and CD14 in biopsy samples of patients with inflammatory bowel diseases: upregulated expression of TLR2 in terminal ileum of patients with ulcerative colitis.

    Lenka Frolova;Pavel Drastich;Pavel Rossmann;Klara Klimesova

  • Oral Administration of Probiotic Escherichia coli after Birth Reduces Frequency of Allergies and Repeated Infections Later in Life (after 10 and 20 Years)

    Rája Lodinová-Zádníková;Bożena Cukrowska;Helena Tlaskalova-Hogenova

  • CD14 is expressed and released as soluble CD14 by human intestinal epithelial cells in vitro: lipopolysaccharide activation of epithelial cells revisited.

    David P. Funda;Ludmila Tučková;Maria A. Farré;Takashi Iwase

  • Specific proliferative and antibody responses of premature infants to intestinal colonization with nonpathogenic probiotic E. coli strain Nissle 1917.

    B Cukrowska;R LodInová-ZádnIková;C Enders;U Sonnenborn

  • Colonization of germ-free mice with a mixture of three lactobacillus strains enhances the integrity of gut mucosa and ameliorates allergic sensitization.

    Hana Kozakova;Martin Schwarzer;Ludmila Tuckova;Dagmar Srutkova

  • Absence of microbiota (germ-free conditions) accelerates the atherosclerosis in ApoE-deficient mice fed standard low cholesterol diet.

    Renata Stepankova;Zbynek Tonar;Jirina Bartova;Lukas Nedorost

  • Gut Microbiota and NAFLD: Pathogenetic Mechanisms, Microbiota Signatures, and Therapeutic Interventions

    Tomas Hrncir;Lucia Hrncirova;Lucia Hrncirova;Miloslav Kverka;Robert Hromadka

  • Intestinal Microbiota Promotes Psoriasis-Like Skin Inflammation by Enhancing Th17 Response

    Zuzana Zákostelská;Jana Málková;Klára Klimešová;Pavel Rossmann

  • Gliadin peptides activate blood monocytes from patients with celiac disease.

    Jana Cinova;Lenka Palová-Jelínková;Lesley E. Smythies;Marie Černá

  • Gliadin fragments induce phenotypic and functional maturation of human dendritic cells.

    Lenka Palová-Jelínková;Daniela Rozková;Barbara Pecharová;Jirina Bártová

  • Colorectal carcinogenesis in germ-free and conventionally reared rats: different intestinal environments affect the systemic immunity.

    Luca Vannucci;Renata Stepankova;Hana Kozakova;Anna Fiserova

  • Mucosal Immunity: Its Role in Defense and Allergy

    Helena Tlaskalová-Hogenová;Ludmila Tucková;Rája Lodinová-Zádniková;Renata Stepánková

Frequent Co-Authors

Karsten Buschard
Karsten Buschard Copenhagen University Hospital
Fiona Powrie
Fiona Powrie University of Oxford
John V. Forrester
John V. Forrester University of Aberdeen
George Howard
George Howard University of Alabama at Birmingham
Ralph B. D'Agostino
Ralph B. D'Agostino Wake Forest University
Leena Mykkänen
Leena Mykkänen The University of Texas Health Science Center at San Antonio
Jiri Mestecky
Jiri Mestecky University of Alabama at Birmingham
Holm H. Uhlig
Holm H. Uhlig University of Oxford
Koichi Kobayashi
Koichi Kobayashi Osaka Metropolitan University
Petr Novák
Petr Novák ETH Zurich

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