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Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

D-Index & Metrics

Medicine

D-Index
87
Citations
29773
World Ranking
13585
National Ranking
148

Overview

Thomas Mandrup-Poulsen is affiliated with the University of Copenhagen in Denmark. Their research spans several areas within medicine and biochemistry, genetics and molecular biology, focusing on topics related to pancreatic function, diabetes, and associated metabolic disorders.

The scientist has contributed to a range of studies primarily published in journals such as bioRxiv (Cold Spring Harbor Laboratory), International Journal of Molecular Sciences, Acta Physiologica, Scientific Reports, and Free Radical Biology and Medicine. Their most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Acta Physiologica
  • Scientific Reports
  • Free Radical Biology and Medicine

Their work covers main fields of study including medicine and biochemistry, genetics and molecular biology. Subfields of particular focus include surgery, physiology, genetics, molecular biology, and epidemiology. The main research topics are:

  • Pancreatic function and diabetes
  • Diabetes and associated disorders
  • Circadian rhythm and melatonin
  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • Dietary Effects on Health
  • Adipose Tissue and Metabolism

Among recent notable research papers coauthored by Thomas Mandrup-Poulsen are:

  • Mitophagy protects β cells from inflammatory damage in diabetes, 2020, JCI Insight
  • GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity, 2020, Frontiers in Immunology
  • Interleukin-6 receptor blockade or TNFα inhibition for reducing glycaemia in patients with RA and diabetes: post hoc analyses of three randomised, controlled trials, 2020, Arthritis Research & Therapy
  • A Blunted GPR183/Oxysterol Axis During Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung During Mycobacterium tuberculosis Infection, 2022, The Journal of Infectious Diseases
  • Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk, 2021, Diabetologia

Thomas Mandrup-Poulsen collaborates frequently with a group of co-authors, including Tina Dahlby, Muhammad Saad Khilji, Michał Marzec, Phillip Alexander Keller Andersen, and Seyed Mojtaba Ghiasi.

Best Publications

  • Interleukin-1-receptor antagonist in type 2 diabetes mellitus.

    Claus M Larsen;Mirjam Faulenbach;Allan Vaag;Allan Vaag;Aage Vølund

  • A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis

    Decio L. Eizirik;T. Mandrup-Poulsen

  • A guiding map for inflammation

    Mihai G Netea;Frances Balkwill;Michel Chonchol;Fabio Cominelli

  • The role of interleukin-1 in the pathogenesis of IDDM.

    T. Mandrup-Poulsen

  • Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells

    Alessandra K. Cardozo;Fernanda Ortis;Joachim Storling;Ying-Mei Feng

  • Interleukin-6 and diabetes : The good, the bad, or the indifferent?

    Ole Peter Kristiansen;Thomas Mandrup-Poulsen

  • Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans.

    Klaus Bendtzen;Thomas Mandrup-Poulsen;Jørn Nerup;Jens H. Nielsen

  • Inflammatory mediators and islet β-cell failure: a link between type 1 and type 2 diabetes

    Marc Y. Donath;Joachim Størling;Kathrin Maedler;Thomas Mandrup-Poulsen;Thomas Mandrup-Poulsen

  • An immune origin of type 2 diabetes

    H. Kolb;T. Mandrup-Poulsen;T. Mandrup-Poulsen

  • RELATION BETWEEN BREAST-FEEDING AND INCIDENCE RATES OF INSULIN-DEPENDENT DIABETES MELLITUS: A Hypothesis

    K. Borch-Johnsen;T. Mandrup-Poulsen;B. Zachau-Christiansen;Geir Joner

  • Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

    Claus M. Larsen;Mirjam Faulenbach;Allan Vaag;Jan A. Ehses

  • Affinity-purified human Interleukin I is cytotoxic to isolated islets of Langerhans

    T. Mandrup-Poulsen;K. Bendtzen;J. Nerup;C. A. Dinarello

  • Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes

    S Baekkeskov;M Landin;J K Kristensen;S Srikanta

  • Role of IL-1beta in type 2 diabetes

    Charles A Dinarello;Marc Y Donath;Thomas Mandrup-Poulsen

  • IL-1 family nomenclature

    Charles Dinarello;William Arend;John Sims;Dirk Smith

  • Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials.

    Antoinette Moran;Brian Bundy;Dorothy J. Becker;Linda A. DiMeglio

  • The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation.

    H. Kolb;T. Mandrup-Poulsen

  • Poor Pregnancy Outcome in Women With Type 2 Diabetes

    Tine D. Clausen;Elisabeth Mathiesen;Pia Ekbom;Ellinor Hellmuth

  • Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.

    T Mandrup-Poulsen;K Bendtzen;C A Dinarello;J Nerup

  • Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

    Claudia Cavelti-Weder;Andrea Babians-Brunner;Cornelia Keller;Marc A. Stahel

Frequent Co-Authors

Flemming Pociot
Flemming Pociot Steno Diabetes Center
Jørn Nerup
Jørn Nerup Steno Diabetes Center
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Marc Y. Donath
Marc Y. Donath University of Basel
Knut Borch-Johnsen
Knut Borch-Johnsen Aarhus University
Oluf Pedersen
Oluf Pedersen University of Copenhagen
Paolo Pozzilli
Paolo Pozzilli Università Campus Bio-Medico
Decio L. Eizirik
Decio L. Eizirik Université Libre de Bruxelles
Klaus Bendtzen
Klaus Bendtzen Rigshospitalet
Hubert Kolb
Hubert Kolb Heinrich Heine University Düsseldorf

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