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Medicine

D-Index
83
Citations
39139
World Ranking
15374
National Ranking
227

Overview

Marc Y. Donath is affiliated with the University of Basel in Switzerland and has contributed extensively to research in medicine, with a focus on endocrinology, diabetes, and metabolism. Their work spans 124 publications in medicine and 40 in biochemistry, genetics, and molecular biology. The scientist's research covers several key subfields, including endocrinology, diabetes and metabolism, surgery, genetics, epidemiology, and molecular biology.

Their research topics primarily focus on diabetes and associated disorders, adipokines, inflammation, and metabolic diseases, pancreatic function and diabetes, diabetes treatment and management, diabetes management and research, bariatric surgery and outcomes, as well as the regulation of appetite and obesity.

Frequent venues for Donath's publications include:

  • Diabetes
  • Endocrine Abstracts
  • Zenodo (CERN European Organization for Nuclear Research)
  • Cell Metabolism
  • Nature Communications

Among notable recent papers are the following:

  • "Inflammation in obesity, diabetes, and related disorders," 2022, Immunity
  • "Continuing versus tapering glucocorticoids after achievement of low disease activity or remission in rheumatoid arthritis (SEMIRA): a double-blind, multicentre, randomised controlled trial," 2020, The Lancet
  • "The cephalic phase of insulin release is modulated by IL-1β," 2022, Cell Metabolism
  • "Distinct Transcriptional Responses across Tissue-Resident Macrophages to Short-Term and Long-Term Metabolic Challenge," 2020, Cell Reports
  • "Postprandial Hypoglycemia in Patients after Gastric Bypass Surgery Is Mediated by Glucose-Induced IL-1β," 2020, Cell Metabolism

The scientist has frequently collaborated with other researchers, including:

  • Daniel T. Meier
  • Leila Rachid
  • Marianne Böni-Schnetzler
  • Matthias Hepprich
  • Sophia J. Wiedemann

Best Publications

  • Type 2 diabetes as an inflammatory disease.

    Marc Y. Donath;Steven E. Shoelson

  • Interleukin-1-receptor antagonist in type 2 diabetes mellitus.

    Claus M Larsen;Mirjam Faulenbach;Allan Vaag;Allan Vaag;Aage Vølund

  • Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets

    Kathrin Maedler;Pavel Sergeev;Frédéric Ris;José Oberholzer

  • Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

    Paul M Ridker;Jean G MacFadyen;Tom Thuren;Brendan M Everett

  • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

    Helga Ellingsgaard;Irina Hauselmann;Beat Schuler;Abdella M Habib

  • Increased Number of Islet-Associated Macrophages in Type 2 Diabetes

    Jan A. Ehses;Aurel Perren;Elisabeth Eppler;Pascale Ribaux

  • Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial

    Paul M Ridker;Jean G MacFadyen;Brendan M Everett;Peter Libby

  • A guiding map for inflammation

    Mihai G Netea;Frances Balkwill;Michel Chonchol;Fabio Cominelli

  • Targeting inflammation in the treatment of type 2 diabetes: time to start

    Marc Y. Donath

  • Distinct Effects of Saturated and Monounsaturated Fatty Acids on β-Cell Turnover and Function

    K. Maedler;G.A. Spinas;D. Dyntar;W. Moritz

  • Monounsaturated Fatty Acids Prevent the Deleterious Effects of Palmitate and High Glucose on Human Pancreatic β-Cell Turnover and Function

    Kathrin Maedler;José Oberholzer;Pascal Alain Robert Bucher;Giatgen A Spinas

  • Inflammatory mediators and islet β-cell failure: a link between type 1 and type 2 diabetes

    Marc Y. Donath;Joachim Størling;Kathrin Maedler;Thomas Mandrup-Poulsen;Thomas Mandrup-Poulsen

  • Mechanisms of β-Cell Death in Type 2 Diabetes

    Marc Y. Donath;Jan A. Ehses;Kathrin Maedler;Desiree M. Schumann

  • Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

    M Y Donath;D J Gross;E Cerasi;N Kaiser

  • Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications

    M. Y. Donath;Philippe A. Halban

  • Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets.

    Kathrin Maedler;Giatgen A. Spinas;Roger Lehmann;Pavel Sergeev

  • Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes

    Claus M. Larsen;Mirjam Faulenbach;Allan Vaag;Jan A. Ehses

  • Sulfonylurea induced beta-cell apoptosis in cultured human islets

    Kathrin Maedler;Richard D. Carr;Domenico Bosco;Richard A. Zuellig

  • Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation.

    Marianne Böni-Schnetzler;Jeffrey Thorne;Géraldine Parnaud;Lorella Marselli

  • Islet inflammation in type 2 diabetes: from metabolic stress to therapy.

    Marc Y. Donath;Desiree M. Schumann;Mirjam Faulenbach;Helga Ellingsgaard

Frequent Co-Authors

Thomas Mandrup-Poulsen
Thomas Mandrup-Poulsen University of Copenhagen
Philippe A. Halban
Philippe A. Halban University of Geneva
Thierry Berney
Thierry Berney University of Geneva
Mirjam Christ-Crain
Mirjam Christ-Crain University of Basel
François Pattou
François Pattou University of Lille
Philipp Schuetz
Philipp Schuetz University of Basel
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Felix Beuschlein
Felix Beuschlein University of Zurich
Allan Vaag
Allan Vaag Steno Diabetes Center
Leo A. B. Joosten
Leo A. B. Joosten Radboud University

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