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D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
9092
World Ranking
18662
National Ranking
7631

Overview

David F. Stowe is affiliated with the Medical College of Wisconsin in the United States. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine, focusing extensively on molecular biology and cardiology.

The scientist's work primarily addresses mitochondrial function and pathology, ATP synthase and ATPases research, cardiac ischemia and reperfusion, cardiomyopathy and myosin studies, muscle physiology and disorders, metabolism and genetic disorders, and trace elements in health.

Frequent coauthors collaborating with David F. Stowe include Amadou K.S. Camara, James S. Heisner, Wai-Meng Kwok, Jyotsna Mishra, and Meiying Yang.

Publications have appeared regularly in journals such as:

  • American Journal Of Pathology
  • Biophysical Journal
  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • Frontiers in Physiology
  • Cells

Recent papers featuring David F. Stowe's contributions include:

  • "Total Matrix Ca2+ Modulates Ca2+ Efflux via the Ca2+/H+ Exchanger in Cardiac Mitochondria" (2020, Frontiers in Physiology)
  • "Knockout of VDAC1 in H9c2 Cells Promotes Oxidative Stress-Induced Cell Apoptosis through Decreased Mitochondrial Hexokinase II Binding and Enhanced Glycolytic Stress" (2020, Cellular Physiology and Biochemistry)
  • "PPARγ-Independent Side Effects of Thiazolidinediones on Mitochondrial Redox State in Rat Isolated Hearts" (2020, Cells)
  • "Modulation of peroxynitrite produced via mitochondrial nitric oxide synthesis during Ca2+ and succinate-induced oxidative stress in cardiac isolated mitochondria" (2020, Biochimica et Biophysica Acta (BBA) - Bioenergetics)
  • "Aberrations in Energetic Metabolism and Stress-Related Pathways Contribute to Pathophysiology in the Neb Conditional Knockout Mouse Model of Nemaline Myopathy" (2023, American Journal Of Pathology)

David F. Stowe's research is situated at the intersection of molecular mechanisms underlying mitochondrial performance, cardiac health, and metabolic disorders. Publications highlight investigations into calcium regulation in mitochondria, oxidative stress, mitochondrial hexokinase interactions, and the biochemical consequences of genetic models of muscle disease.

Best Publications

  • Mitochondrial Reactive Oxygen Species Production in Excitable Cells: Modulators of Mitochondrial and Cell Function

    David F. Stowe;Amadou K. S. Camara

  • Ischemic preconditioning alters real-time measure of O2 radicals in intact hearts with ischemia and reperfusion

    Leo G. Kevin;Amadou K. S. Camara;Matthias L. Riess;Enis Novalija

  • Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion

    Qun Chen;Amadou K. S. Camara;David F. Stowe;David F. Stowe;David F. Stowe;Charles L. Hoppel

  • Reactive oxygen species as mediators of cardiac injury and protection: the relevance to anesthesia practice.

    Leo G. Kevin;Enis Novalija;David F. Stowe

  • Sevoflurane mimics ischemic preconditioning effects on coronary flow and nitric oxide release in isolated hearts.

    Enis Novalija;Satoshi Fujita;John P. Kampine;David F. Stowe

  • Potential therapeutic benefits of strategies directed to mitochondria.

    Amadou K.S. Camara;Edward J. Lesnefsky;Edward J. Lesnefsky;David F. Stowe

  • Comparison of etomidate, ketamine, midazolam, propofol, and thiopental on function and metabolism of isolated hearts.

    David F. Stowe;Zeljko J. Bosnjak;John P. Kampine

  • Cardiac mitochondrial preconditioning by Big Ca2+-sensitive K+ channel opening requires superoxide radical generation

    David F. Stowe;Mohammed Aldakkak;Amadou K. S. Camara;Matthias L. Riess

  • Sevoflurane exposure generates superoxide but leads to decreased superoxide during ischemia and reperfusion in isolated hearts.

    Leo G. Kevin;Enis Novalija;Matthias L. Riess;Amadou K. S. Camara

  • Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury.

    Amadou K. S. Camara;Martin Bienengraeber;David F. Stowe

  • Reduced reactive O2 species formation and preserved mitochondrial NADH and [Ca2+] levels during short-term 17 °C ischemia in intact hearts

    Matthias L Riess;Amadou K S Camara;Leo G Kevin;Jianzhong An

  • Xenon does not alter cardiac function or major cation currents in isolated guinea pig hearts or myocytes.

    David F. Stowe;Georg C. Rehmert;Wai-Meng Kwok;Henry U. Weigt

  • Mitochondrial Ca2+-induced K+ influx increases respiration and enhances ROS production while maintaining membrane potential.

    Andre Heinen;Amadou Camara;Mohammed Aldakkak;Samhita Shahane Rhodes

  • Reactive Oxygen Species Precede the ε Isoform of Protein Kinase C in the Anesthetic Preconditioning Signaling Cascade

    Enis Novalija;Leo G. Kevin;Amadou K.S. Camara;Zeljko J. Bosnjak

  • Inhibited mitochondrial respiration by amobarbital during cardiac ischaemia improves redox state and reduces matrix Ca2+ overload and ROS release.

    Mohammed Aldakkak;David F. Stowe;Qun Chen;Edward J. Lesnefsky;Edward J. Lesnefsky

  • Cardiac pharmacological preconditioning with volatile anesthetics: from bench to bedside?

    Matthias L. Riess;David F. Stowe;David C. Warltier

  • Ranolazine reduces Ca2+ overload and oxidative stress and improves mitochondrial integrity to protect against ischemia reperfusion injury in isolated hearts.

    Mohammed Aldakkak;Amadou K.S. Camara;James S. Heisner;Meiying Yang

  • Anesthetic preconditioning: triggering role of reactive oxygen and nitrogen species in isolated hearts.

    Enis Novalija;Srinivasan G. Varadarajan;Amadou K. S. Camara;Jianzhong An

  • Blocking Na+/H+ exchange reduces [Na+]i and [Ca2+]i load after ischemia and improves function in intact hearts

    Jianzhong An;Srinivasan G. Varadarajan;Amadou Camara;Qun Chen

  • Changes in [Na+]i, compartmental [Ca2+], and NADH with dysfunction after global ischemia in intact hearts

    Srinivasan G. Varadarajan;Jianzhong An;Enis Novalija;Steven C. Smart

Frequent Co-Authors

Edward J. Lesnefsky
Edward J. Lesnefsky Virginia Commonwealth University
Garrett J. Gross
Garrett J. Gross Medical College of Wisconsin
Eike Martin
Eike Martin Heidelberg University
Paul S. Pagel
Paul S. Pagel Medical College of Wisconsin
David R. Harder
David R. Harder Medical College of Wisconsin
William W. Parmley
William W. Parmley University of California, San Francisco
William E. Antholine
William E. Antholine Medical College of Wisconsin
Emad Tajkhorshid
Emad Tajkhorshid University of Illinois at Urbana-Champaign
Chandrajit L. Bajaj
Chandrajit L. Bajaj The University of Texas at Austin
Stanton A. Glantz
Stanton A. Glantz University of California, San Francisco

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