Miguel A. Aon mainly investigates Mitochondrion, Biochemistry, Biophysics, Reactive oxygen species and Oxidative phosphorylation. His Mitochondrion research includes themes of Oxidative stress, Homeostasis, Membrane potential, Skeletal muscle and Superoxide. His work on Respiratory chain, Mitochondrial matrix and Citric acid cycle as part of general Biochemistry research is frequently linked to Perilipin, thereby connecting diverse disciplines of science.
While the research belongs to areas of Biophysics, Miguel A. Aon spends his time largely on the problem of Reverse electron flow, intersecting his research to questions surrounding Electron transport chain and Thioredoxin reductase. Miguel A. Aon interconnects Heart metabolism, Glutathione and Depolarization in the investigation of issues within Reactive oxygen species. His work deals with themes such as Beta oxidation, Insulin resistance and Myocyte, Lipid droplet, Cell biology, which intersect with Oxidative phosphorylation.
His primary areas of study are Mitochondrion, Biochemistry, Internal medicine, Biophysics and Cell biology. His biological study spans a wide range of topics, including Oxidative stress, Reactive oxygen species, Oxidative phosphorylation and Membrane potential. His studies in Reactive oxygen species integrate themes in fields like Heart metabolism, Glutathione, Superoxide and Intracellular.
His Internal medicine course of study focuses on Cardiology and Pharmacology. His studies deal with areas such as Myocyte, Uniporter, Respiratory chain and Cellular respiration as well as Biophysics. His Cell biology research incorporates elements of Downregulation and upregulation, Cytoskeleton and NAD+ kinase.
His primary areas of investigation include Mitochondrion, Cell biology, Internal medicine, Endocrinology and Biochemistry. His Mitochondrion study combines topics from a wide range of disciplines, such as Cardiac myocyte, Biophysics and Energetics. His Cardiac myocyte research integrates issues from Membrane potential, Depolarization and Streptozotocin.
The Cell biology study combines topics in areas such as Oxidative stress, Stress induced and Downregulation and upregulation. His Internal medicine study integrates concerns from other disciplines, such as Autophagy and Respiratory chain. Miguel A. Aon has included themes like Lipid oxidation, Mitochondrial disease and Myopathy in his Endocrinology study.
Miguel A. Aon mostly deals with Mitochondrion, Cell biology, Internal medicine, Endocrinology and Sirtuin. His Mitochondrion study contributes to a more complete understanding of Biochemistry. His study in the field of Bioenergetics, Axon, Signal transduction and MitoQ also crosses realms of Coupling.
His work in the fields of Endocrinology, such as Steatosis, Cholesterol and GDF15, overlaps with other areas such as Population. His Sirtuin study incorporates themes from Acetyl-CoA, Histone acetyltransferase, Histone methyltransferase and Pyruvate dehydrogenase complex. The NAD+ kinase study combines topics in areas such as Carcinogenesis, Inflammation and Downregulation and upregulation.
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Synchronized Whole Cell Oscillations in Mitochondrial Metabolism Triggered by a Local Release of Reactive Oxygen Species in Cardiac Myocytes
Miguel A. Aon;Sonia Cortassa;Eduardo Marbán;Brian O'Rourke.
Journal of Biological Chemistry (2003)
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics
Sonia Cortassa;Miguel A. Aon;Eduardo Marbán;Raimond L. Winslow.
Biophysical Journal (2003)
II. Temporal and spatial evolution of enzymatic activities and physico-chemical properties in an agricultural soil
M.A Aon;A.C Colaneri.
Applied Soil Ecology (2001)
Elevated Cytosolic Na+ Decreases Mitochondrial Ca2+ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptation in Cardiac Myocytes
Christoph Maack;Sonia Cortassa;Miguel A. Aon;Anand N. Ganesan.
Circulation Research (2006)
Antiarrhythmic Engineering of Skeletal Myoblasts for Cardiac Transplantation
M. Roselle Abraham;Charles A. Henrikson;Leslie Tung;Marvin G. Chang.
Circulation Research (2005)
The mitochondrial origin of postischemic arrhythmias
Fadi G. Akar;Miguel A. Aon;Gordon F. Tomaselli;Brian O’Rourke.
Journal of Clinical Investigation (2005)
Redox-optimized ROS balance: A unifying hypothesis
M.A. Aon;S. Cortassa;B. O'Rourke.
Biochimica et Biophysica Acta (2010)
Mitochondrial ion channels: gatekeepers of life and death.
Brian O'Rourke;Sonia Cortassa;Miguel A. Aon.
Physiology (2005)
Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca2+ Cycling
Carlo G. Tocchetti;Wang Wang;Jeffrey P. Froehlich;Sabine Huke.
Circulation Research (2007)
I. Spatio-temporal patterns of soil microbial and enzymatic activities in an agricultural soil
M.A Aon;M.N Cabello;D.E Sarena;A.C Colaneri.
Applied Soil Ecology (2001)
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