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Biology and Biochemistry

D-Index
52
Citations
10433
World Ranking
16633
National Ranking
6881

Overview

Sonia Cortassa is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broader areas, their work focuses intensively on Molecular Biology, Physiology, Electrical and Electronic Engineering, Pathology and Forensic Medicine, and Endocrine and Autonomic Systems.

The main topics addressed in their publications include mitochondrial function and pathology, ATP synthase and ATPases research, adipose tissue and metabolism, fuel cells and related materials, cardiac ischemia and reperfusion, circadian rhythm and melatonin, and metabolomics and mass spectrometry studies.

Among their recent papers are:

  • "ATP Synthase K+- and H+-Fluxes Drive ATP Synthesis and Enable Mitochondrial K+-'Uniporter' Function: I. Characterization of Ion Fluxes" (2021) published in Function
  • "Mitochondrial Ca2+, redox environment and ROS emission in heart failure: Two sides of the same coin?" (2020) published in Journal of Molecular and Cellular Cardiology
  • "ATP Synthase K+- and H+-fluxes Drive ATP Synthesis and Enable Mitochondrial K+-'Uniporter' Function: II. Ion and ATP Synthase Flux Regulation" (2022) published in Function
  • "Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan" (2021) published in npj Aging and Mechanisms of Disease
  • "Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice" (2022) published in npj Aging

Frequent coauthors collaborating with Sonia Cortassa include:

  • Miguel A. Aon
  • Steven J. Sollott
  • Magdalena Juhaszova
  • Dmitry B. Zorov
  • Evgeny Kobrinsky

The scientist has published repeatedly in venues such as Biophysical Journal, Function, Journal of Molecular and Cellular Cardiology, npj Aging and Mechanisms of Disease, and npj Aging. Biophysical Journal accounts for four of their publications, Function for three, Journal of Molecular and Cellular Cardiology for two, and one publication each in npj Aging and Mechanisms of Disease and npj Aging.

Best Publications

  • Synchronized Whole Cell Oscillations in Mitochondrial Metabolism Triggered by a Local Release of Reactive Oxygen Species in Cardiac Myocytes

    Miguel A. Aon;Sonia Cortassa;Eduardo Marbán;Brian O'Rourke

  • An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics

    Sonia Cortassa;Miguel A. Aon;Eduardo Marbán;Raimond L. Winslow

  • Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

    Sarah J. Mitchell;Julio Madrigal-Matute;Morten Scheibye-Knudsen;Morten Scheibye-Knudsen;Evandro Fang

  • Elevated Cytosolic Na+ Decreases Mitochondrial Ca2+ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptation in Cardiac Myocytes

    Christoph Maack;Sonia Cortassa;Miguel A. Aon;Anand N. Ganesan

  • Redox-optimized ROS balance: A unifying hypothesis

    M.A. Aon;S. Cortassa;B. O'Rourke

  • Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure

    Alexander G. Nickel;Albrecht Von Hardenberg;Mathias Hohl;Joachim R. Löffler

  • Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

    Sarah J. Mitchell;Michel Bernier;Miguel A. Aon;Sonia Cortassa

  • Mitochondrial ion channels: gatekeepers of life and death.

    Brian O'Rourke;Sonia Cortassa;Miguel A. Aon

  • I. Spatio-temporal patterns of soil microbial and enzymatic activities in an agricultural soil

    M.A Aon;M.N Cabello;D.E Sarena;A.C Colaneri

  • Mitochondrial and cellular mechanisms for managing lipid excess

    Miguel A. Aon;Niraj Bhatt;Sonia C. Cortassa

  • A Mitochondrial Oscillator Dependent on Reactive Oxygen Species

    Sonia Cortassa;Miguel A. Aon;Raimond L. Winslow;Brian O’Rourke

  • A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte

    Sonia Cortassa;Miguel A. Aon;Brian O'Rourke;Robert Jacques

  • Percolation and criticality in a mitochondrial network.

    Miguel A. Aon;Sonia Cortassa;Brian O'Rourke

  • Sequential Opening of Mitochondrial Ion Channels as a Function of Glutathione Redox Thiol Status

    Miguel A. Aon;Sonia Cortassa;Christoph Maack;Brian O'Rourke

  • Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: an experimental-computational study.

    Miguel Antonio Aon;Brian Alan Stanley;Vidhya Sivakumaran;Jackelyn Melissa Kembro

  • Redox-Optimized ROS Balance and the relationship between mitochondrial respiration and ROS

    Sonia Cortassa;Brian O'Rourke;Miguel A. Aon

  • The Fundamental Organization of Cardiac Mitochondria as a Network of Coupled Oscillators

    Miguel Antonio Aon;Sonia Cortassa;Brian O'Rourke

  • From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales

    Gernot Plank;Lufang Zhou;Joseph L Greenstein;Sonia Cortassa

  • Why homeodynamics, not homeostasis?

    David Lloyd;Miguel A. Aon;Sonia Cortassa

  • Mitochondrial Oscillations in Physiology and Pathophysiology

    Miguel A. Aon;Sonia Cortassa;Brian O’Rourke

Frequent Co-Authors

Miguel A. Aon
Miguel A. Aon National Institutes of Health
Brian O'Rourke
Brian O'Rourke Johns Hopkins University
Hans V. Westerhoff
Hans V. Westerhoff Vrije Universiteit Amsterdam
Dmitry B. Zorov
Dmitry B. Zorov Lomonosov Moscow State University
Gernot Plank
Gernot Plank Medical University of Graz
Rafael de Cabo
Rafael de Cabo National Institutes of Health
José M. Villalba
José M. Villalba University of Córdoba
Michel Bernier
Michel Bernier National Institutes of Health
Edward G. Lakatta
Edward G. Lakatta National Institutes of Health
Eduardo Marbán
Eduardo Marbán Cedars-Sinai Medical Center

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