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Medicine

D-Index
81
Citations
26319
World Ranking
16553
National Ranking
8318

Overview

Jesper Gromada is affiliated with Regeneron in the United States. Their research spans several interconnected fields, primarily focused on Medicine as well as Biochemistry, Genetics, and Molecular Biology. Key subfields within their work include Genetics, Endocrinology, Diabetes and Metabolism, Surgery, Physiology, and Cardiology and Cardiovascular Medicine.

The scientist's research attention centers notably on pancreatic function and diabetes, covering related areas such as diabetes and associated disorders, genetics and neurodevelopmental disorders, lipid metabolism and disorders, diabetes with cardiovascular risks and lipoproteins, diabetes treatment and management, and connections between metabolism, diabetes, and cancer.

Jesper Gromada has contributed to several recent papers, among which are:

  • Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance, 2020, Journal of Lipid Research
  • Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells, 2020, Journal of Biological Chemistry
  • Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency, 2022, Communications Biology
  • Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency, 2023, Science Translational Medicine
  • Human stem cell model of HNF1A deficiency shows uncoupled insulin to C-peptide secretion with accumulation of abnormal insulin granules, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Jesper Gromada include:

  • Bryan J. González
  • Haoquan Zhao
  • Jacqueline Niu
  • Damian J. Williams
  • Jaeyop Lee

Their publications are distributed across several venues, including:

  • Journal of Lipid Research
  • Journal of Biological Chemistry
  • Communications Biology
  • Science Translational Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • FGF-21 as a novel metabolic regulator

    Alexei Kharitonenkov;Tatiyana L. Shiyanova;Anja Koester;Amy M. Ford

  • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

    Helga Ellingsgaard;Irina Hauselmann;Beat Schuler;Abdella M Habib

  • Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.

    Jens Juul Holst;Jesper Gromada

  • Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

    Frederick E Dewey;Viktoria Gusarova;Richard L Dunbar;Colm T O'Dushlaine

  • RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes.

    Yurong Xin;Jinrang Kim;Haruka Okamoto;Min Ni

  • Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains.

    Jesper Gromada;Isobel Franklin;Claes B. Wollheim

  • A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease

    Noura S. Abul-Husn;Xiping Cheng;Alexander H. Li;Yurong Xin

  • Fibroblast Growth Factor-21 Improves Pancreatic β-Cell Function and Survival by Activation of Extracellular Signal–Regulated Kinase 1/2 and Akt Signaling Pathways

    Wolf Wente;Alexander M. Efanov;Martin Brenner;Alexei Kharitonenkov

  • Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

    Frederick E. Dewey;Viktoria Gusarova;Colm O'Dushlaine;Omri Gottesman

  • The Cell Physiology of Biphasic Insulin Secretion

    Patrik Rorsman;Lena Eliasson;Erik Renström;Jesper Gromada

  • Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis

    Yan Wang;Fabiana Quagliarini;Viktoria Gusarova;Jesper Gromada

  • β-Cell Secretory Products Activate α-Cell ATP-Dependent Potassium Channels to Inhibit Glucagon Release

    Isobel Franklin;Jesper Gromada;Asllan Gjinovci;Sten Theander

  • Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis

    Eriks Smagris;Soumik Basuray;John Li;Yongcheng Huang

  • Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.

    J. Gromada;Jens Juul Holst;Patrik Rorsman

  • Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression

    Karishma Rahman;Yuliya Vengrenyuk;Stephen A. Ramsey;Noemi Rotllan Vila

  • ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia.

    Daniel Gaudet;Daniel A. Gipe;Robert Pordy;Zahid Ahmad

  • Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells.

    Anna Wendt;Bryndis Birnir;Karsten Buschard;Jesper Gromada

  • SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.

    Lena Eliasson;Xiaosong Ma;Erik Renström;Sebastian Barg

  • Regulation of glucagon release in mouse -cells by KATP channels and inactivation of TTX-sensitive Na+ channels.

    Sven Göpel;T Kanno;Sebastian Barg;X G Weng

  • Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose.

    Chiyo Shiota;Olof Larsson;Kathy D. Shelton;Masakazu Shiota

Frequent Co-Authors

Andrew J. Murphy
Andrew J. Murphy St. Jude Children's Research Hospital
George D. Yancopoulos
George D. Yancopoulos Regeneron (United States)
Alan R. Shuldiner
Alan R. Shuldiner University of Maryland, Baltimore
Helen H. Hobbs
Helen H. Hobbs The University of Texas Southwestern Medical Center
Patrik Rorsman
Patrik Rorsman University of Oxford
William C. Olson
William C. Olson Regeneron (United States)
Per-Olof Berggren
Per-Olof Berggren Karolinska Institute
Lena Eliasson
Lena Eliasson Lund University
Jason Flannick
Jason Flannick Broad Institute

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