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Francesc Villarroya

Francesc Villarroya

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
33439
World Ranking
3630
National Ranking
42

Overview

Francesc Villarroya is affiliated with the University of Barcelona in Spain. Their research output prominently spans the intersection of medicine and biochemistry, genetics, and molecular biology.

Their primary fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these disciplines, Villarroya has focused on subfields such as:

  • Physiology
  • Molecular Biology
  • Epidemiology
  • Cardiology and Cardiovascular Medicine
  • Rheumatology

The main research topics that characterize Villarroya's work are:

  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiovascular Disease and Adiposity
  • Liver Disease Diagnosis and Treatment
  • GDF15 and Related Biomarkers
  • HIV-related health complications and treatments
  • Birth, Development, and Health

Villarroya has published extensively, contributing to several journals with notable frequency. Venues with multiple publications include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • International Journal of Molecular Sciences
  • Scientific Reports
  • Journal of the Endocrine Society
  • Nature Metabolism

Recent significant papers include:

  • SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation, 2020, Signal Transduction and Targeted Therapy
  • The endocrine role of brown adipose tissue: An update on actors and actions, 2021, Reviews in Endocrine and Metabolic Disorders
  • Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation, 2021, Nature Metabolism
  • Meteorin-like/Meteorin-β protects heart against cardiac dysfunction, 2021, The Journal of Experimental Medicine
  • Cyanidin-3-O-glucoside restores insulin signaling and reduces inflammation in hypertrophic adipocytes, 2020, Archives of Biochemistry and Biophysics

Collaborations have been an important aspect of Villarroya's research, with frequent co-authorship alongside researchers such as:

  • Marta Giralt
  • Rubén Cereijo
  • Aleix Gavaldà-Navarro
  • Joan Villarroya
  • Tania Quesada-López

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

    Elayne Hondares;Roser Iglesias;Albert Giralt;Frank J. Gonzalez

  • Brown adipose tissue as a secretory organ

    Francesc Villarroya;Rubén Cereijo;Joan Villarroya;Marta Giralt

  • BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

    Andrew J. Whittle;Stefania Carobbio;Luís Martins;Marc Slawik;Marc Slawik

  • White, Brown, Beige/Brite: Different Adipose Cells for Different Functions?

    Marta Giralt;Francesc Villarroya

  • GLP-1 Agonism Stimulates Brown Adipose Tissue Thermogenesis and Browning Through Hypothalamic AMPK

    Daniel Beiroa;Monica Imbernon;Rosalía Gallego;Ana Senra

  • Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.

    M. José Barberá;Agatha Schlüter;Neus Pedraza;Roser Iglesias

  • Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.

    Elayne Hondares;Meritxell Rosell;Frank J. Gonzalez;Marta Giralt

  • Fibroblast growth factor 21 protects against cardiac hypertrophy in mice.

    A. Planavila;I. Redondo;E. Hondares;M. Vinciguerra;M. Vinciguerra

  • Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

    Elayne Hondares;Meritxell Rosell;Julieta Díaz-Delfín;Yolanda Olmos

  • Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

    Ana Planavila;Roser Iglesias;Marta Giralt;Francesc Villarroya

  • SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging

    Albert Giralt;Francesc Villarroya

  • SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-γ co-activator-1α(PGC-1α) gene in skeletal muscle through the PGC-1α autoregulatory loop and interaction with MyoD

    Ramon Amat;Anna Planavila;Shen Liang Chen;Roser Iglesias

  • Inflammation of brown/beige adipose tissues in obesity and metabolic disease

    F. Villarroya;R. Cereijo;A. Gavaldà-Navarro;J. Villarroya

  • Fibroblast growth factor 21 protects the heart from oxidative stress

    Anna Planavila;Ibon Redondo-Angulo;Francesc Ribas;Gloria Garrabou

  • Browning of White Adipose Cells by Intermediate Metabolites:An Adaptive Mechanism to Alleviate Redox Pressure

    Audrey Carrière;Yannick Jeanson;Sandra Berger-Müller;Mireille André

  • Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation.

    Elayne Hondares;Ofelia Mora;Pilar Yubero;Marisa Rodriguez de la Concepción

  • Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.

    Stéphane Fourcade;Jone López-Erauskin;Jorge Galino;Carine Duval

  • Beyond the sympathetic tone: the new brown fat activators.

    Francesc Villarroya;Antonio Vidal-Puig;Antonio Vidal-Puig

  • PPARs in the Control of Uncoupling Proteins Gene Expression.

    Francesc Villarroya;Roser Iglesias;Marta Giralt

Frequent Co-Authors

Marta Giralt
Marta Giralt University of Barcelona
Pere Domingo
Pere Domingo Autonomous University of Barcelona
Lourdes Ibáñez
Lourdes Ibáñez Sant Joan de Déu Barcelona Hopital
Manuel Vázquez-Carrera
Manuel Vázquez-Carrera University of Barcelona
Gema Frühbeck
Gema Frühbeck University of Navarra
Antonio Vidal-Puig
Antonio Vidal-Puig University of Cambridge
Aurora Pujol
Aurora Pujol Institut d'Investigació Biomédica de Bellvitge
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Rafael Artuch
Rafael Artuch Instituto de Salud Carlos III

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