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Biology and Biochemistry

D-Index
67
Citations
14946
World Ranking
8267
National Ranking
140

Overview

Marta Giralt is affiliated with the University of Barcelona in Spain. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields including Physiology, Molecular Biology, Epidemiology, Emergency Medicine, and Cardiology and Cardiovascular Medicine.

The scientist's main topics of work encompass adipose tissue and metabolism, adipokines, inflammation, and metabolic diseases. Additional research interests include HIV-related health complications and treatments, cardiovascular disease and adiposity, fibroblast growth factor research, peroxisome proliferator-activated receptors, and the regulation of appetite and obesity.

Marta Giralt has authored numerous papers, among which the recent publications include:

  • "The endocrine role of brown adipose tissue: An update on actors and actions," 2021, Reviews in Endocrine and Metabolic Disorders
  • "The kallikrein-kinin pathway as a mechanism for auto-control of brown adipose tissue activity," 2020, Nature Communications
  • "FGF15/19 is required for adipose tissue plasticity in response to thermogenic adaptations," 2020, Molecular Metabolism
  • "The chemokine CXCL14 is negatively associated with obesity and concomitant type-2 diabetes in humans," 2021, International Journal of Obesity
  • "Differential effects of dolutegravir, bictegravir and raltegravir in adipokines and inflammation markers on human adipocytes," 2022, Life Sciences

Frequent co-authors with whom Marta Giralt has collaborated include Francesc Villarroya, Aleix Gavaldà-Navarro, Rubén Cereijo, Tania Quesada-López, and Joan Villarroya.

Their research findings are frequently published in journals such as the International Journal of Obesity, International Journal of Molecular Sciences, Molecular Metabolism, Molecular Therapy - Nucleic Acids, and Biochemical Pharmacology.

Best Publications

  • Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

    Elayne Hondares;Roser Iglesias;Albert Giralt;Frank J. Gonzalez

  • Brown adipose tissue as a secretory organ

    Francesc Villarroya;Rubén Cereijo;Joan Villarroya;Marta Giralt

  • White, Brown, Beige/Brite: Different Adipose Cells for Different Functions?

    Marta Giralt;Francesc Villarroya

  • Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.

    M. José Barberá;Agatha Schlüter;Neus Pedraza;Roser Iglesias

  • Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.

    Elayne Hondares;Meritxell Rosell;Frank J. Gonzalez;Marta Giralt

  • Fibroblast growth factor 21 protects against cardiac hypertrophy in mice.

    A. Planavila;I. Redondo;E. Hondares;M. Vinciguerra;M. Vinciguerra

  • Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

    Elayne Hondares;Meritxell Rosell;Julieta Díaz-Delfín;Yolanda Olmos

  • Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

    Ana Planavila;Roser Iglesias;Marta Giralt;Francesc Villarroya

  • SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-γ co-activator-1α(PGC-1α) gene in skeletal muscle through the PGC-1α autoregulatory loop and interaction with MyoD

    Ramon Amat;Anna Planavila;Shen Liang Chen;Roser Iglesias

  • Inflammation of brown/beige adipose tissues in obesity and metabolic disease

    F. Villarroya;R. Cereijo;A. Gavaldà-Navarro;J. Villarroya

  • Fibroblast growth factor 21 protects the heart from oxidative stress

    Anna Planavila;Ibon Redondo-Angulo;Francesc Ribas;Gloria Garrabou

  • Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation.

    Elayne Hondares;Ofelia Mora;Pilar Yubero;Marisa Rodriguez de la Concepción

  • PPARs in the Control of Uncoupling Proteins Gene Expression.

    Francesc Villarroya;Roser Iglesias;Marta Giralt

  • Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients

    J M Gallego-Escuredo;J Gómez-Ambrosi;V Catalan;P Domingo

  • A Novel Regulatory Pathway of Brown Fat Thermogenesis RETINOIC ACID IS A TRANSCRIPTIONAL ACTIVATOR OF THE MITOCHONDRIAL UNCOUPLING PROTEIN GENE

    Rosa Alvarez;Javier de Andrés;Pilar Yubero;Octavi Viñas

  • Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth.

    S Brun;M C Carmona;T Mampel;O Viñas

  • Peroxisome Proliferator-activated Receptor-γ Coactivator-1α Controls Transcription of the Sirt3 Gene, an Essential Component of the Thermogenic Brown Adipocyte Phenotype

    Albert Giralt;Elayne Hondares;Josep A. Villena;Francesc Ribas

  • CXCL14, a Brown Adipokine that Mediates Brown-Fat-to-Macrophage Communication in Thermogenic Adaptation

    Rubén Cereijo;Aleix Gavaldà-Navarro;Montserrat Cairó;Tania Quesada-López

  • The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes.

    Tania Quesada-López;Rubén Cereijo;Jean-Valery Turatsinze;Anna Planavila

  • TNF-α Represses β-Klotho Expression and Impairs FGF21 Action in Adipose Cells: Involvement of JNK1 in the FGF21 Pathway

    Julieta Díaz-Delfín;Elayne Hondares;Roser Iglesias;Marta Giralt

Frequent Co-Authors

Francesc Villarroya
Francesc Villarroya University of Barcelona
Pere Domingo
Pere Domingo Autonomous University of Barcelona
Gema Frühbeck
Gema Frühbeck University of Navarra
José Manuel Fernández-Real
José Manuel Fernández-Real University of Girona
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Javier Gómez-Ambrosi
Javier Gómez-Ambrosi University of Navarra
Richard W. Hanson
Richard W. Hanson Case Western Reserve University
Antoni L. Andreu
Antoni L. Andreu Autonomous University of Barcelona
Jinsong Liu
Jinsong Liu The University of Texas MD Anderson Cancer Center
Marçal Pastor-Anglada
Marçal Pastor-Anglada University of Barcelona

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