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Herbert Y. Gaisano

Herbert Y. Gaisano

University of Toronto
Canada

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
12433
World Ranking
7584
National Ranking
261

Herbert Y. Gaisano publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Herbert Y. Gaisano sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 250 publications — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Herbert Y. Gaisano D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Herbert Y. Gaisano sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 69 D-Index — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Herbert Y. Gaisano is affiliated with the University of Toronto in Canada. Their research primarily focuses on medicine with particular emphasis on biochemistry, genetics, and molecular biology. The subfields most frequently addressed include surgery, endocrinology, diabetes and metabolism, epidemiology, molecular biology, and cardiology and cardiovascular medicine.

The scientist's work revolves around several central topics such as pancreatic function and diabetes, pancreatitis pathology and treatment, cellular transport and secretion, diabetes management and research, diabetes linked with cardiovascular risks and lipoproteins, adipokines, inflammation, and metabolic diseases, as well as diabetes treatment and management.

Recent publications highlight their contributions to the understanding of metabolic and pancreatic diseases. Notable papers include:

  • "Elevated triglyceride-glucose (TyG) index predicts incidence of Prediabetes: a prospective cohort study in China," published in 2020 in Lipids in Health and Disease
  • "Relationship of obesity to adipose tissue insulin resistance," published in 2020 in BMJ Open Diabetes Research & Care
  • "Gut microbiome modified by bariatric surgery improves insulin sensitivity and correlates with increased brown fat activity and energy expenditure," published in 2023 in Cell Reports Medicine
  • "Dysregulation of mannose-6-phosphate-dependent cholesterol homeostasis in acinar cells mediates pancreatitis," published in 2021 in Journal of Clinical Investigation
  • "Pancreas-specific SNAP23 depletion prevents pancreatitis by attenuating pathological basolateral exocytosis and formation of trypsin-activating autolysosomes," published in 2020 in Autophagy

Frequent collaborators in their research include Fei Kang, Yan He, Yingting Zuo, Qi Zhai, and Jiajia Jiang. The scientist has also contributed extensively to several high-profile publication venues such as bioRxiv (Cold Spring Harbor Laboratory), BMJ Open Diabetes Research & Care, iScience, Diabetes Obesity and Metabolism, and Endocrine.

The body of work conducted by Herbert Y. Gaisano integrates clinical and molecular perspectives on pancreatic diseases, metabolic dysfunctions, and diabetes-related complications. Their publications reflect a strong interdisciplinary approach, merging surgery, endocrinology, and molecular biology to address complex health issues.

Best Publications

  • Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

    N. Wijesekara;F. F. Dai;A. B. Hardy;P. R. Giglou

  • Characterization of SNARE protein expression in beta cell lines and pancreatic islets.

    M B Wheeler;L Sheu;M Ghai;A Bouquillon

  • Impaired Gene and Protein Expression of Exocytotic Soluble N-Ethylmaleimide Attachment Protein Receptor Complex Proteins in Pancreatic Islets of Type 2 Diabetic Patients

    Claes-Goran Ostenson;Herbert Gaisano;Laura Sheu;Annika Tibell

  • Members of the Kv1 and Kv2 Voltage-Dependent K+ Channel Families Regulate Insulin Secretion

    Patrick E. MacDonald;Xiao Fang Ha;Jing Wang;Simon R. Smukler

  • Distinct cellular locations of the syntaxin family of proteins in rat pancreatic acinar cells.

    H Y Gaisano;M Ghai;P N Malkus;L Sheu

  • Disruption of Pancreatic β-Cell Lipid Rafts Modifies Kv2.1 Channel Gating and Insulin Exocytosis

    Fuzhen Xia;Xiaodong Gao;Edwin Kwan;Patrick P.L. Lam

  • Gut-associated IgA+ immune cells regulate obesity-related insulin resistance

    Helen Luck;Helen Luck;Saad Khan;Saad Khan;Justin H. Kim;Julia K. Copeland

  • Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice

    Benjamin J. Lamont;Yazhou Li;Edwin Kwan;Theodore J. Brown

  • Inhibition of cholesterol biosynthesis impairs insulin secretion and voltage-gated calcium channel function in pancreatic beta-cells.

    Fuzhen Xia;Li Xie;Anton Mihic;Xiaodong Gao

  • Caspase-3-Dependent β-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus

    Nicole Liadis;Kiichi Murakami;Mohamed Eweida;Alisha R. Elford

  • α/β-Hydrolase Domain-6-Accessible Monoacylglycerol Controls Glucose-Stimulated Insulin Secretion

    Shangang Zhao;Yves Mugabo;Jose Iglesias;Li Xie

  • New Insights Into the Mechanisms of Pancreatitis

    Herbert Y. Gaisano;Fred S. Gorelick

  • Tetanus toxin light chain cleaves a vesicle-associated membrane protein (VAMP) isoform 2 in rat pancreatic zymogen granules and inhibits enzyme secretion.

    H Y Gaisano;L Sheu;J K Foskett;W S Trimble

  • Syntaxin 1A binds to the cytoplasmic C terminus of Kv2.1 to regulate channel gating and trafficking.

    Yuk M. Leung;Youhou Kang;Xiaodong Gao;Fuzhen Xia

  • Erythropoietin protects against diabetes through direct effects on pancreatic β cells

    Diana Choi;Stephanie A. Schroer;Shun Yan Lu;Linyuan Wang

  • Regulation of insulin exocytosis by Munc13-1

    Laura Sheu;Eva A. Pasyk;Junzhi Ji;Xiaohang Huang

  • Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment.

    Herbert Y. Gaisano;Claes-Goran Ostenson;Laura Sheu;Michael B. Wheeler

  • Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane

    Herbert Y. Gaisano;Manfred P. Lutz;Juergen Leser;Laura Sheu

  • SUMOylation Regulates Insulin Exocytosis Downstream of Secretory Granule Docking in Rodents and Humans

    Xiao-Qing Dai;Greg Plummer;Marina Casimir;Youhou Kang

  • Truncated SNAP-25 (1–197), Like Botulinum Neurotoxin A, Can Inhibit Insulin Secretion from HIT-T15 Insulinoma Cells

    Xiaohang Huang;Michael B. Wheeler;You-hou Kang;Laura Sheu

Frequent Co-Authors

Michael B. Wheeler
Michael B. Wheeler University of Toronto
William S. Trimble
William S. Trimble University of Toronto
Laurence J. Miller
Laurence J. Miller Mayo Clinic
Per-Olof Berggren
Per-Olof Berggren Karolinska Institute
Vesa M. Olkkonen
Vesa M. Olkkonen University of Helsinki
Patricia L. Brubaker
Patricia L. Brubaker University of Toronto
Stephen J. Pandol
Stephen J. Pandol Cedars-Sinai Medical Center
Christopher B. Newgard
Christopher B. Newgard Duke University
Kris Chadee
Kris Chadee University of Calgary
Nils Brose
Nils Brose Max Planck Society

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Best Scientists Citing Herbert Y. Gaisano

Laurence J. Miller

Laurence J. Miller

Mayo Clinic

Publications: 50

Michael B. Wheeler

Michael B. Wheeler

University of Toronto

Publications: 49

Patrik Rorsman

Patrik Rorsman

University of Oxford

Publications: 45

Guy A. Rutter

Guy A. Rutter

Imperial College London

Publications: 39

Per-Olof Berggren

Per-Olof Berggren

Karolinska Institute

Publications: 34

Stephen J. Pandol

Stephen J. Pandol

Cedars-Sinai Medical Center

Publications: 31

Daniel J. Drucker

Daniel J. Drucker

Lunenfeld-Tanenbaum Research Institute

Publications: 26

Lena Eliasson

Lena Eliasson

Lund University

Publications: 25

Marc Prentki

Marc Prentki

University of Montreal

Publications: 24

Anna L. Gloyn

Anna L. Gloyn

Stanford University

Publications: 24

Piero Marchetti

Piero Marchetti

University of Pisa

Publications: 23

Wanjin Hong

Wanjin Hong

Agency for Science, Technology and Research

Publications: 21

Cesare Montecucco

Cesare Montecucco

University of Padua

Publications: 21

Louis H. Philipson

Louis H. Philipson

University of Chicago

Publications: 21

Mark I. McCarthy

Mark I. McCarthy

Genentech

Publications: 20

George G. Holz

George G. Holz

SUNY Upstate Medical University

Publications: 19

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