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Yoshihisa Kurachi

Yoshihisa Kurachi

D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
26764
World Ranking
2835
National Ranking
178

Overview

Yoshihisa Kurachi is affiliated with Osaka University in Japan, focusing on research within Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several key areas including cardiology, molecular biology, and biomedical engineering.

The scientist's research topics cover:

  • Cardiac electrophysiology and arrhythmias
  • Ion channel regulation and function
  • ECG Monitoring and Analysis
  • Microfluidic and Capillary Electrophoresis Applications
  • Cardiac Ischemia and Reperfusion

Kurachi has contributed to multiple publications with frequent appearances in notable venues such as:

  • IUPHAR/BPS Guide to Pharmacology CITE
  • Scientific Reports
  • npj Systems Biology and Applications

Significant recent papers include:

  • Specific decreasing of Na+ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome, 2020, Scientific Reports
  • Inwardly rectifying potassium channels (KIR) in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Inwardly rectifying potassium channels (KIR) in GtoPdb v.2021.3, 2021, IUPHAR/BPS Guide to Pharmacology CITE
  • Author Correction: Computer modeling defines the system driving a constant current crucial for homeostasis in the mammalian cochlea by integrating unique ion transports, 2021, npj Systems Biology and Applications

Throughout their career, Kurachi has collaborated with various researchers, including:

  • Hiroshi Hibino
  • John P. Adelman
  • David E. Clapham
  • Atsushi Inanobe
  • Lily Yeh Jan

The scientist's subfield expertise extends to Cardiology and Cardiovascular Medicine, Molecular Biology, Biomedical Engineering, and Pathology and Forensic Medicine. This diverse foundation supports their investigation into ion channels and cardiac function, particularly regarding electrical activity and arrhythmias in heart tissue.

Best Publications

  • Inwardly Rectifying Potassium Channels: Their Structure, Function, and Physiological Roles

    Hiroshi Hibino;Atsushi Inanobe;Kazuharu Furutani;Shingo Murakami

  • The βγ subunits of GTP-binding proteins activate the muscarinic K + channel in heart

    Diomedes E. Logothetis;Yoshihisa Kurachi;Jonas Galper;Eva J. Neer

  • Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.

    Y Ohta;Y Tanizawa;H Inoue;T Hosaka

  • A Novel Sulfonylurea Receptor Forms with BIR (Kir6.2) a Smooth Muscle Type ATP-sensitive K+ Channel

    Shojiro Isomoto;Chikako Kondo;Mitsuhiko Yamada;Shigeto Matsumoto

  • On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins.

    Yoshihisa Kurachi;Toshiaki Nakajima;TsuNeaki Sugimoto

  • Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains

    Erlend A. Nagelhus;Yoshiyuki Horio;Atsushi Inanobe;Akikazu Fujita

  • International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels

    George A. Gutman;K. George Chandy;John P. Adelman;Jayashree Aiyar

  • Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea‐sensitive but ATP‐insensitive K+ channel.

    M Yamada;S Isomoto;S Matsumoto;C Kondo

  • G Protein Regulation of Potassium Ion Channels

    Mitsuhiko Yamada;Atsushi Inanobe;Yoshihisa Kurachi

  • Arachidonic acid metabolites as intracellular modulators of the G protein-gated cardiac K+ channel

    Yoshihisa Kurachi;Hiroyuki Ito;Tsuneaki Sugimoto;Takao Shimizu

  • An inwardly rectifying K(+) channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain.

    Kayoko Higashi;Akikazu Fujita;Atsushi Inanobe;Masayuki Tanemoto

  • Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs

    A. Terzic;Arshad Jahangir;Y. Kurachi

  • International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of Inwardly Rectifying Potassium Channels

    Yoshihiro Kubo;John P. Adelman;David E. Clapham;Lily Y. Jan

  • Inwardly rectifying potassium channels: their molecular heterogeneity and function.

    Shojiro Isomoto;Chikako Kondo;Yoshihisa Kurachi

  • A Novel ATP-dependent Inward Rectifier Potassium Channel Expressed Predominantly in Glial Cells

    Toru Takumi;Takahiro Ishii;Yoshiyuki Horio;Ken-Ichirou Morishige

  • Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra

    Atsushi Inanobe;Yukiko Yoshimoto;Yoshiyuki Horio;Ken-Ichiro Morishige

  • Expression and Clustered Distribution of an Inwardly Rectifying Potassium Channel, KAB-2/Kir4.1, on Mammalian Retinal Müller Cell Membrane: Their Regulation by Insulin and Laminin Signals

    Masaru Ishii;Yoshiyuki Horio;Yoshihiko Tada;Hiroshi Hibino

  • Muscarinic acetylcholine receptors.

    Masaru Ishii;Yoshihisa Kurachi

  • Molecular and Physiological Bases of the K+ Circulation in the Mammalian Inner Ear

    Hiroshi Hibino;Yoshihisa Kurachi

  • On the mechanism of G protein beta gamma subunit activation of the muscarinic K+ channel in guinea pig atrial cell membrane. Comparison with the ATP-sensitive K+ channel.

    H Ito;R T Tung;T Sugimoto;I Kobayashi

Frequent Co-Authors

Yoshiyuki Horio
Yoshiyuki Horio Sapporo Medical University
Masaru Ishii
Masaru Ishii Osaka University
Andre Terzic
Andre Terzic Mayo Clinic
Masao Omata
Masao Omata University of Tokyo
Atsushi Nakagawa
Atsushi Nakagawa Osaka University
Toru Takumi
Toru Takumi Kobe University
David E. Clapham
David E. Clapham Howard Hughes Medical Institute
Yoshimi Takai
Yoshimi Takai Kobe University
Haruki Nakamura
Haruki Nakamura Osaka University
Takeshi Kubo
Takeshi Kubo Osaka University

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