Makoto Ojika

Overview

Best Publications

• Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter

  Masami Suganuma;Hirota Fujiki;Hiroko Suguri;Shigeru Yoshizawa

  834
  Citations

• Structure-activity relationship within a series of okadaic acid derivatives.

  Shinji Nishiwaki;Hirota Fujiki;Masami Suganuma;Hiroko Furuya-Suguri

  197
  Citations

• Aplyronine A, a potent antitumor substance and the congeners aplyronines B and C isolated from the sea hare Aplysia kurodai

  Kiyoyuki Yamada;Makoto Ojika;Takeshi Ishigaki;Yoshifumi Yoshida

  190
  Citations

• Ptaquiloside, a novel norsesquiterpene glucoside from bracken, var.

  Haruki Niwa;Makoto Ojika;Kazumasa Wakamatsu;Kiyoyuki Yamada

  168
  Citations

• Firefly luciferase is a bifunctional enzyme: ATP-dependent monooxygenase and a long chain fatty acyl-CoA synthetase.

  Yuichi Oba;Makoto Ojika;Satoshi Inouye

  144
  Citations

• Cystothiazoles A and B, new bithiazole-type antibiotics from the myxobacterium Cystobacter fuscus.

  Makoto Ojika;Yoshihiro Suzuki;Akane Tsukamoto;Youji Sakagami

  138
  Citations

• Ptaquiloside, the major toxin of bracken, and related terpene glycosides: chemistry, biology and ecology.

  Kiyoyuki Yamada;Makoto Ojika;Hideo Kigoshi

  129
  Citations

• Ptaquiloside, a potent carcinogen isolated from bracken fern Pteridium aquilinum var. latiusculum: structure elucidation based on chemical and spectral evidence, and reactions with amino acids, nucleosides, and nucleotides

  Makoto Ojika;Kazumasa Wakamatsu;Haruki Niwa;Kiyoyuki Yamada

  128
  Citations

• Aplyronine A, a Potent Antitumor Substance of Marine Origin, Aplyronines B and C, and Artificial Analogues: Total Synthesis and Structure−Cytotoxicity Relationships

  Hideo Kigoshi;Kiyotake Suenaga;Tsuyoshi Mutou;Takeshi Ishigaki

  125
  Citations

• Dolabellin, a Cytotoxic Bisthiazole Metabolite from the Sea Hare Dolabella auricularia: Structural Determination and Synthesis

  Hiroki Sone;Takashi Kondo;Minoru Kiryu;Hiroyuki Ishiwata

  117
  Citations

• Total Synthesis of Aplyronine A, a Potent Antitumor Substance of Marine Origin

  Hideo Kigoshi;Makoto Ojika;Takeshi Ishigaki;Kiyotake Suenaga

  116
  Citations

• Absolute Stereochemistry of Aplyronine A, a Potent Antitumor Substance of Marine Origin

  Makoto Ojika;Hideo Kigoshi;Takeshi Ishigaki;Itaru Tsukada

  112
  Citations

• Coffee and Caffeine Ameliorate Hyperglycemia, Fatty Liver, and Inflammatory Adipocytokine Expression in Spontaneously Diabetic KK-Ay Mice

  Rie Yamauchi;Misato Kobayashi;Yuji Matsuda;Makoto Ojika

  107
  Citations

• Amphimic acids and related long-chain fatty acids as DNA topoisomerase I inhibitors from an Australian sponge, Amphimedon sp.: Isolation, structure, synthesis, and biological evaluation

  Takayuki Nemoto;Go Yoshino;Makoto Ojika;Youji Sakagami

  100
  Citations

• Soft-tissue evidence for homeothermy and crypsis in a Jurassic ichthyosaur

  Johan Lindgren;Peter Sjövall;Volker Thiel;Wenxia Zheng

  99
  Citations

• DNA damage by ptaquiloside, a potent bracken carcinogen: detection of selective strand breaks and identification of DNA cleavage products

  Tatsushi Kushida;Motonari Uesugi;Yukio Sugiura;Hideo Kigoshi

  97
  Citations

• Termitomycesphins A–D, Novel Neuritogenic Cerebrosides from the Edible Chinese Mushroom Termitomyces albuminosus

  Jianhua Qi;Makoto Ojika;Youji Sakagami

  97
  Citations

• Isolation and stereostructure of doliculide, a cytotoxic cyclodepsipeptide from the Japanese sea hare Dolabella auricularia

  Hiroyuki Ishiwata;Takayuki Nemoto;Makoto Ojika;Kiyoyuki Yamada

  94
  Citations

• Cystothiazoles C-F, new bithiazole-type antibiotics from the myxobacterium Cystobacter fuscus

  Yoshihiro Suzuki;Makoto Ojika;Youji Sakagami;Ryosuke Fudou

  94
  Citations

• Tyrosinase-catalyzed oxidation of rhododendrol produces 2-methylchromane-6,7-dione, the putative ultimate toxic metabolite: implications for melanocyte toxicity

  Shosuke Ito;Makoto Ojika;Toshiharu Yamashita;Kazumasa Wakamatsu

  93
  Citations