D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 87 Citations 23,220 206 World Ranking 1835 National Ranking 1038

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

The scientist’s investigation covers issues in Eukaryotic initiation factor, Initiation factor, Biochemistry, Eukaryotic translation and Protein biosynthesis. His Eukaryotic initiation factor study incorporates themes from Molecular biology, Eukaryotic initiation factor 4F, eIF2 and eIF4A. The study incorporates disciplines such as Eukaryotic translation initiation factor 4 gamma, EIF4B, EIF4A1 and Protein phosphorylation in addition to Initiation factor.

His Eukaryotic translation research is multidisciplinary, incorporating elements of Internal ribosome entry site and Cell biology. His studies deal with areas such as EIF4E and Five prime untranslated region as well as Internal ribosome entry site. His Protein biosynthesis study combines topics from a wide range of disciplines, such as Translation, Elongation factor, Ribosome and Protein subunit.

His most cited work include:

  • Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F. (554 citations)
  • Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin (542 citations)
  • GTP-binding domain: three consensus sequence elements with distinct spacing (493 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Biochemistry, Eukaryotic initiation factor, Initiation factor, Eukaryotic translation and Cell biology. His study in Biochemistry concentrates on Protein biosynthesis, Messenger RNA, Ribosome, Reticulocyte and RNA. The Eukaryotic initiation factor study combines topics in areas such as eIF2, Internal ribosome entry site, Eukaryotic initiation factor 4F, Molecular biology and EIF4E.

In his study, GTP' is inextricably linked to Protein subunit, which falls within the broad field of Initiation factor. His Eukaryotic translation research focuses on subjects like Eukaryotic translation initiation factor 4 gamma, which are linked to EIF4A1. William C. Merrick focuses mostly in the field of Cell biology, narrowing it down to matters related to Translation and, in some cases, Gene silencing and In vitro.

He most often published in these fields:

  • Biochemistry (53.04%)
  • Eukaryotic initiation factor (41.99%)
  • Initiation factor (35.91%)

What were the highlights of his more recent work (between 2009-2020)?

  • Cell biology (32.04%)
  • Translation (27.62%)
  • Biochemistry (53.04%)

In recent papers he was focusing on the following fields of study:

William C. Merrick mostly deals with Cell biology, Translation, Biochemistry, Eukaryotic translation and Protein biosynthesis. His Cell biology study integrates concerns from other disciplines, such as Integrated stress response, Eukaryotic Small Ribosomal Subunit, Messenger RNA and eIF2. His Translation research is multidisciplinary, relying on both RNA, Ribosome and Ribosomal RNA.

His research is interdisciplinary, bridging the disciplines of Cytotrienin A and Biochemistry. His Eukaryotic translation research is multidisciplinary, incorporating perspectives in Internal ribosome entry site, Computational biology, eIF4A and Initiation factor. The various areas that he examines in his Initiation factor study include Eukaryotic translation initiation factor 4 gamma, Translational regulation, Molecular biology, EIF4A1 and EIF4E.

Between 2009 and 2020, his most popular works were:

  • Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin (542 citations)
  • mRNA helicases:the tacticians of translational control (242 citations)
  • Identification of an mRNP complex regulating tumorigenesis at the translational elongation step (134 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Translation, Cell biology, Eukaryotic translation, Protein biosynthesis and Initiation factor are his primary areas of study. His Translation study introduces a deeper knowledge of Biochemistry. His work in Protein biosynthesis covers topics such as Ribosome which are related to areas like Cycloheximide, Transfer RNA and Messenger RNA.

His research integrates issues of eIF4A, Eukaryotic initiation factor and Eukaryotic Ribosome in his study of Initiation factor. His eIF4A research includes themes of EIF4G, EIF4B, Eukaryotic initiation factor 4F, Molecular biology and EIF4E. His work carried out in the field of Eukaryotic Ribosome brings together such families of science as eIF2, EIF1, Five prime untranslated region, Internal ribosome entry site and T arm.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

Tilman Schneider-Poetsch;Jianhua Ju;Daniel E Eyler;Yongjun Dang.
Nature Chemical Biology (2010)

881 Citations

Mechanism and regulation of eukaryotic protein synthesis.

W C Merrick.
Microbiological Research (1992)

797 Citations

Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F.

Florence Rozen;Isaac Edery;Karen Meerovitch;Thomas E. Dever.
Molecular and Cellular Biology (1990)

792 Citations

GTP-binding domain: three consensus sequence elements with distinct spacing

Thomas E. Dever;Manuel J. Glynias;William C. Merrick.
Proceedings of the National Academy of Sciences of the United States of America (1987)

754 Citations

MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F

Géraldine Mathonnet;Marc R. Fabian;Yuri V. Svitkin;Armen Parsyan.
Science (2007)

743 Citations

The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation

Hsin Sheng Yang;Aaron P. Jansen;Anton A. Komar;Xiaojing Zheng.
Molecular and Cellular Biology (2003)

581 Citations

ATP-dependent unwinding of messenger RNA structure by eukaryotic initiation factors

B K Ray;T G Lawson;J C Kramer;M H Cladaras.
Journal of Biological Chemistry (1985)

458 Citations

Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.

Arnim Pause;Nathalie Méthot;Yuri Svitkin;William C. Merrick.
The EMBO Journal (1994)

453 Citations

New initiation factor activity required for globin mRNA translation.

J A Grifo;S M Tahara;M A Morgan;A J Shatkin.
Journal of Biological Chemistry (1983)

442 Citations

A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5'-terminal cap in mRNA

Nahum Sonenberg;Maureen A. Morgan;William C. Merrick;Aaron J. Shatkin.
Proceedings of the National Academy of Sciences of the United States of America (1978)

429 Citations

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