Brian Safer

Overview

Best Publications

• Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase

  Jan Kitajewski;Robert J. Schneider;Brian Safer;Susan M. Munemitsu

  477
  Citations

• Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles.

  John A. Chiorini;Linda Yang;Yuejiang Liu;Brian Safer

  344
  Citations

• The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.

  T L Black;B Safer;A Hovanessian;M G Katze

  249
  Citations

• Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner.

  Paul A. Ney;Nancy C. Andrews;Stephen M. Jane;Brian Safer

  209
  Citations

• Evidence for role of m7G5'-phosphate group in recognition of eukaryotic mRNA by initiation factor IF-M3.

  David A. Shafritz;Joel A. Weinstein;Brian Safer;William C. Merrick

  207
  Citations

• Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection

  Robert J. Schneider;Brian Safer;Susan M. Munemitsu;Charles E. Samuel

  197
  Citations

• Purification and physical properties of homogeneous initiation factor MP from rabbit reticulocytes.

  B Safer;W F Anderson;W C Merrick

  196
  Citations

• Competition between cellular and viral mRNAs in vitro is regulated by a messenger discriminatory initiation factor.

  F. Golini;S. S. Thach;C. H. Birge;B. Safer

  193
  Citations

• Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep protein.

  E Urcelay;P Ward;S M Wiener;B Safer

  185
  Citations

• High-efficiency transfer of the T cell co-stimulatory molecule B7-2 to lymphoid cells using high-titer recombinant adeno-associated virus vectors.

  John A. Chiorini;Clemens M. Wendtner;Elena Urcelay;Brian Safer

  184
  Citations

• Mitochondrial-Cytosolic Interactions in Perfused Rat Heart ROLE OF COUPLED TRANSAMINATION IN REPLETION OF CITRIC ACID CYCLE INTERMEDIATES

  Brian Safer;John R. Williamson

  184
  Citations

• Biologically active Rep proteins of adeno-associated virus type 2 produced as fusion proteins in Escherichia coli.

  J A Chiorini;M D Weitzman;R A Owens;E Urcelay

  169
  Citations

• Control of the transport of reducing equivalents across the mitochondrial membrane in perfused rat heart

  Brian Safer;Colleen M. Smith;John R. Williamson

  163
  Citations

• Sequence requirements for stable binding and function of Rep68 on the adeno-associated virus type 2 inverted terminal repeats.

  J. A. Chiorini;S. M. Wiener;R. A. Owens;S. R. M. Kyostio

  160
  Citations

• Eukaryotic Initiation Complex Formation EVIDENCE FOR TWO DISTINCT PATHWAYS

  S. L. Adams;B. Safer;W. F. Anderson;William C. Merrick

  155
  Citations

• Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase.

  M. G. Katze;J. Tomita;T. Black;R. M. Krug

  149
  Citations

• Binding and release of radiolabeled eukaryotic initiation factors 2 and 3 during 80 S initiation complex formation.

  D. T. Peterson;William C. Merrick;B. Safer

  144
  Citations

• Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs.

  M. G. Katze;B. M. Detjen;B. Safer;Robert M Krug

  134
  Citations

• Binding of MET-TRNAf and GTP to homogeneous initiation factor MP.

  B Safer;SL Adams;WF Anderson;WC Merrick

  133
  Citations

• T-cell Activation Leads to Rapid Stimulation of Translation Initiation Factor eIF2B and Inactivation of Glycogen Synthase Kinase-3

  Gavin I. Welsh;Suzanne Miyamoto;Nigel T. Price;Brian Safer

  131
  Citations