His primary areas of investigation include Genetic enhancement, Virology, Stem cell, Viral vector and Haematopoiesis. His Genetic enhancement research is multidisciplinary, incorporating elements of Vector, Factor IX, CD34, Molecular biology and Leukemia. His Molecular biology research is multidisciplinary, incorporating perspectives in Complementary DNA and Gene.
His work in Stem cell addresses subjects such as Bone marrow, which are connected to disciplines such as Genetic transfer and Cancer research. His studies in Viral vector integrate themes in fields like Vesicular stomatitis virus and Transplantation. His study looks at the relationship between Haematopoiesis and topics such as Simian immunodeficiency virus, which overlap with Hematopoietic stem cell, Murine leukemia virus and Genome.
His main research concerns Molecular biology, Genetic enhancement, Viral vector, Gene and Haematopoiesis. His Molecular biology study integrates concerns from other disciplines, such as Promoter, Gene expression, Locus control region, Green fluorescent protein and Globin. His Genetic enhancement research incorporates elements of Virology, Vector, Factor IX, Immunology and CD34.
His Viral vector research includes elements of Insertional mutagenesis, Genetic transfer, Transfection, Transduction and Hematopoietic stem cell. Arthur W. Nienhuis works mostly in the field of Haematopoiesis, limiting it down to topics relating to Bone marrow and, in certain cases, Lymphocyte and Myeloid, as a part of the same area of interest. His study in Stem cell is interdisciplinary in nature, drawing from both Cancer research and Transplantation.
Viral vector, Genetic enhancement, Molecular biology, Immunology and Factor IX are his primary areas of study. His research integrates issues of Genome, CD34, Restriction enzyme and Transplantation in his study of Viral vector. He interconnects Haematopoiesis, Cancer research, Vector, B cell and Wiskott–Aldrich syndrome in the investigation of issues within Genetic enhancement.
The Molecular biology study combines topics in areas such as Virology, Globin, Gene, Green fluorescent protein and Promoter. His Immunology research incorporates themes from Thalassemia, Beta thalassemia, Endocrinology and Red Cell. His Factor IX study combines topics in areas such as Virus, Immunosuppression, Clinical trial and Transgene.
Arthur W. Nienhuis spends much of his time researching Immunology, Genetic enhancement, Molecular biology, Virus and Factor IX. Arthur W. Nienhuis combines subjects such as Thalassemia, Internal medicine and Fetal hemoglobin with his study of Immunology. His Genetic enhancement study incorporates themes from Vector and Immune system.
His Molecular biology research is multidisciplinary, relying on both Viral vector and Polymerase chain reaction. His Factor IX research is multidisciplinary, incorporating perspectives in Clinical trial, Transgene and Ion chromatography. Asymptomatic is closely connected to Gastroenterology in his research, which is encompassed under the umbrella topic of Transgene.
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Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B
Amit C. Nathwani;Edward G.D. Tuddenham;Savita Rangarajan;Cecilia Rosales.
The New England Journal of Medicine (2011)
Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major.
Gary M. Brittenham;Patricia M. Griffith;Arthur W. Nienhuis;Christine E. McLaren.
The New England Journal of Medicine (1994)
Long-term safety and efficacy of factor IX gene therapy in hemophilia B
Amit C Nathwani;Ulreke M Reiss;Edward G D Tuddenham;Cecilia Rosales;Cecilia Rosales.
The New England Journal of Medicine (2014)
Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1.
Brian P. Sorrentino;Stephen J. Brandt;David Bodine;Michael Gottesman.
Science (1992)
Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy.
Gary Kurtzman;Norbert Frickhofen;Janice Kimball;Douglas W. Jenkins.
The New England Journal of Medicine (1989)
Genotoxicity of Retroviral Integration In Hematopoietic Cells
Arthur W. Nienhuis;Cynthia E. Dunbar;Brian P. Sorrentino.
Molecular Therapy (2006)
Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells
David M. Bodine;Stefan Karlsson;Arthur W. Nienhuis.
Proceedings of the National Academy of Sciences of the United States of America (1989)
Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.
Peiman Hematti;Bum Kee Hong;Cole Ferguson;Rima Adler.
PLOS Biology (2004)
Bone Marrow-derived Cells Contribute to Tumor Neovasculature and, When Modified to Express an Angiogenesis Inhibitor, Can Restrict Tumor Growth in Mice
Andrew M. Davidoff;Catherine Y. C. Ng;Peggy Brown;Margaret A. Leary.
Clinical Cancer Research (2001)
Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.
Derek A. Persons;James A. Allay;Esther R. Allay;Richard A. Ashmun.
Blood (1999)
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