D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 87 Citations 20,449 216 World Ranking 725 National Ranking 408

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Internal medicine

His primary areas of investigation include Genetic enhancement, Virology, Stem cell, Viral vector and Haematopoiesis. His Genetic enhancement research is multidisciplinary, incorporating elements of Vector, Factor IX, CD34, Molecular biology and Leukemia. His Molecular biology research is multidisciplinary, incorporating perspectives in Complementary DNA and Gene.

His work in Stem cell addresses subjects such as Bone marrow, which are connected to disciplines such as Genetic transfer and Cancer research. His studies in Viral vector integrate themes in fields like Vesicular stomatitis virus and Transplantation. His study looks at the relationship between Haematopoiesis and topics such as Simian immunodeficiency virus, which overlap with Hematopoietic stem cell, Murine leukemia virus and Genome.

His most cited work include:

  • Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B (1262 citations)
  • Long-term safety and efficacy of factor IX gene therapy in hemophilia B (719 citations)
  • Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major. (688 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Molecular biology, Genetic enhancement, Viral vector, Gene and Haematopoiesis. His Molecular biology study integrates concerns from other disciplines, such as Promoter, Gene expression, Locus control region, Green fluorescent protein and Globin. His Genetic enhancement research incorporates elements of Virology, Vector, Factor IX, Immunology and CD34.

His Viral vector research includes elements of Insertional mutagenesis, Genetic transfer, Transfection, Transduction and Hematopoietic stem cell. Arthur W. Nienhuis works mostly in the field of Haematopoiesis, limiting it down to topics relating to Bone marrow and, in certain cases, Lymphocyte and Myeloid, as a part of the same area of interest. His study in Stem cell is interdisciplinary in nature, drawing from both Cancer research and Transplantation.

He most often published in these fields:

  • Molecular biology (41.33%)
  • Genetic enhancement (36.22%)
  • Viral vector (31.63%)

What were the highlights of his more recent work (between 2009-2020)?

  • Viral vector (31.63%)
  • Genetic enhancement (36.22%)
  • Molecular biology (41.33%)

In recent papers he was focusing on the following fields of study:

Viral vector, Genetic enhancement, Molecular biology, Immunology and Factor IX are his primary areas of study. His research integrates issues of Genome, CD34, Restriction enzyme and Transplantation in his study of Viral vector. He interconnects Haematopoiesis, Cancer research, Vector, B cell and Wiskott–Aldrich syndrome in the investigation of issues within Genetic enhancement.

The Molecular biology study combines topics in areas such as Virology, Globin, Gene, Green fluorescent protein and Promoter. His Immunology research incorporates themes from Thalassemia, Beta thalassemia, Endocrinology and Red Cell. His Factor IX study combines topics in areas such as Virus, Immunosuppression, Clinical trial and Transgene.

Between 2009 and 2020, his most popular works were:

  • Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B (1262 citations)
  • Long-term safety and efficacy of factor IX gene therapy in hemophilia B (719 citations)
  • Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins. (215 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Internal medicine

Arthur W. Nienhuis spends much of his time researching Immunology, Genetic enhancement, Molecular biology, Virus and Factor IX. Arthur W. Nienhuis combines subjects such as Thalassemia, Internal medicine and Fetal hemoglobin with his study of Immunology. His Genetic enhancement study incorporates themes from Vector and Immune system.

His Molecular biology research is multidisciplinary, relying on both Viral vector and Polymerase chain reaction. His Factor IX research is multidisciplinary, incorporating perspectives in Clinical trial, Transgene and Ion chromatography. Asymptomatic is closely connected to Gastroenterology in his research, which is encompassed under the umbrella topic of Transgene.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

Amit C. Nathwani;Edward G.D. Tuddenham;Savita Rangarajan;Cecilia Rosales.
The New England Journal of Medicine (2011)

1672 Citations

Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major.

Gary M. Brittenham;Patricia M. Griffith;Arthur W. Nienhuis;Christine E. McLaren.
The New England Journal of Medicine (1994)

988 Citations

Long-term safety and efficacy of factor IX gene therapy in hemophilia B

Amit C Nathwani;Ulreke M Reiss;Edward G D Tuddenham;Cecilia Rosales;Cecilia Rosales.
The New England Journal of Medicine (2014)

931 Citations

Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1.

Brian P. Sorrentino;Stephen J. Brandt;David Bodine;Michael Gottesman.
Science (1992)

707 Citations

Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy.

Gary Kurtzman;Norbert Frickhofen;Janice Kimball;Douglas W. Jenkins.
The New England Journal of Medicine (1989)

524 Citations

Genotoxicity of Retroviral Integration In Hematopoietic Cells

Arthur W. Nienhuis;Cynthia E. Dunbar;Brian P. Sorrentino.
Molecular Therapy (2006)

421 Citations

Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells

David M. Bodine;Stefan Karlsson;Arthur W. Nienhuis.
Proceedings of the National Academy of Sciences of the United States of America (1989)

362 Citations

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.

Peiman Hematti;Bum Kee Hong;Cole Ferguson;Rima Adler.
PLOS Biology (2004)

305 Citations

Bone Marrow-derived Cells Contribute to Tumor Neovasculature and, When Modified to Express an Angiogenesis Inhibitor, Can Restrict Tumor Growth in Mice

Andrew M. Davidoff;Catherine Y. C. Ng;Peggy Brown;Margaret A. Leary.
Clinical Cancer Research (2001)

297 Citations

Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

Derek A. Persons;James A. Allay;Esther R. Allay;Richard A. Ashmun.
Blood (1999)

289 Citations

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