The scientist’s investigation covers issues in Genetic enhancement, Immunology, Transgene, Vector and Immune system. His Genetic enhancement research includes elements of Virus, Virology, Retinal and Disease. In his work, Adeno-associated virus and Cytotoxic T cell is strongly intertwined with CD8, which is a subfield of Virology.
Immunology is frequently linked to Factor IX in his study. His Factor IX study integrates concerns from other disciplines, such as Gastroenterology, Viral vector and Transduction. His research in Immune system tackles topics such as Antigen which are related to areas like Toxicity, T cell, Gene product and Immunity.
Federico Mingozzi mainly investigates Genetic enhancement, Immunology, Immune system, Virology and Transgene. His study in Genetic enhancement is interdisciplinary in nature, drawing from both Internal medicine, Clinical trial, Disease, Bioinformatics and Vector. His Immunology research incorporates elements of Factor IX and Genetic transfer.
His research on Immune system often connects related topics like Antibody. Federico Mingozzi combines subjects such as Adeno-associated virus, Epitope and CD8 with his study of Virology. His work in Transgene addresses subjects such as Transduction, which are connected to disciplines such as In vivo, Immunity and Cell biology.
His primary areas of study are Genetic enhancement, Disease, Virology, Cancer research and Internal medicine. His Genetic enhancement study incorporates themes from Vector, Immune system, Transduction, Antibody and In vivo. The concepts of his Immune system study are interwoven with issues in Bilirubin, Virus, Adeno-associated virus and Pharmacology.
His studies in Adeno-associated virus integrate themes in fields like In vitro, Neutralizing antibody, Immunology, Immunity and Hepatocellular carcinoma. His Disease research is multidisciplinary, incorporating elements of Ophthalmology, Cataracts, Viral vector and Immune tolerance. The Virology study combines topics in areas such as Cytotoxic T cell, Innate immune system, Glycogen storage disease and Transgene.
The scientist’s investigation covers issues in Genetic enhancement, Vector, Virus, Immunogenicity and Internal medicine. Federico Mingozzi has researched Genetic enhancement in several fields, including Bioinformatics, Immunosuppression, Muscular dystrophy, Duchenne muscular dystrophy and Disease. His work carried out in the field of Vector brings together such families of science as Epitope, Cytotoxic T cell, Innate immune system and Neuromuscular disease.
Federico Mingozzi has included themes like Adeno-associated virus, Immune system and Antigen in his Virus study. Immune system is a primary field of his research addressed under Immunology. Federico Mingozzi interconnects Cancer research, Computational biology and Gene delivery in the investigation of issues within Immunogenicity.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
Albert M. Maguire;Francesca Simonelli;Eric A. Pierce;Edward N. Pugh.
The New England Journal of Medicine (2008)
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
Manno Cs;Pierce Gf;Arruda Vr;Glader B.
Nature Medicine (2006)
Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B
Amit C. Nathwani;Edward G.D. Tuddenham;Savita Rangarajan;Cecilia Rosales.
The New England Journal of Medicine (2011)
Long-term safety and efficacy of factor IX gene therapy in hemophilia B
Amit C Nathwani;Ulreke M Reiss;Edward G D Tuddenham;Cecilia Rosales;Cecilia Rosales.
The New England Journal of Medicine (2014)
Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
Federico Mingozzi;Katherine A. High;Katherine A. High.
Nature Reviews Genetics (2011)
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial
Albert M. Maguire;Albert M. Maguire;Katherine A. High;Katherine A. High;Alberto Auricchio;J. Fraser Wright;J. Fraser Wright.
The Lancet (2009)
Immune responses to AAV vectors: overcoming barriers to successful gene therapy
Federico Mingozzi;Katherine A. High;Katherine A. High;Katherine A. High.
CD8(+) T-cell responses to adeno-associated virus capsid in humans.
Federico Mingozzi;Marcela V Maus;Marcela V Maus;Daniel J Hui;Denise E Sabatino.
Nature Medicine (2007)
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.
Francesca Simonelli;Albert M Maguire;Albert M Maguire;Francesco Testa;Eric A Pierce.
Molecular Therapy (2010)
Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer
Federico Mingozzi;Yi-Lin Liu;Eric Dobrzynski;Antje Kaufhold.
Journal of Clinical Investigation (2003)
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