D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 56 Citations 20,223 163 World Ranking 2698 National Ranking 1281

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

The scientist’s investigation covers issues in Genetic enhancement, Immunology, Transgene, Vector and Immune system. His Genetic enhancement research includes elements of Virus, Virology, Retinal and Disease. In his work, Adeno-associated virus and Cytotoxic T cell is strongly intertwined with CD8, which is a subfield of Virology.

Immunology is frequently linked to Factor IX in his study. His Factor IX study integrates concerns from other disciplines, such as Gastroenterology, Viral vector and Transduction. His research in Immune system tackles topics such as Antigen which are related to areas like Toxicity, T cell, Gene product and Immunity.

His most cited work include:

  • Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis (1728 citations)
  • Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response (1561 citations)
  • Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B (1262 citations)

What are the main themes of his work throughout his whole career to date?

Federico Mingozzi mainly investigates Genetic enhancement, Immunology, Immune system, Virology and Transgene. His study in Genetic enhancement is interdisciplinary in nature, drawing from both Internal medicine, Clinical trial, Disease, Bioinformatics and Vector. His Immunology research incorporates elements of Factor IX and Genetic transfer.

His research on Immune system often connects related topics like Antibody. Federico Mingozzi combines subjects such as Adeno-associated virus, Epitope and CD8 with his study of Virology. His work in Transgene addresses subjects such as Transduction, which are connected to disciplines such as In vivo, Immunity and Cell biology.

He most often published in these fields:

  • Genetic enhancement (36.13%)
  • Immunology (36.13%)
  • Immune system (35.48%)

What were the highlights of his more recent work (between 2015-2021)?

  • Genetic enhancement (36.13%)
  • Disease (9.03%)
  • Virology (32.26%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Genetic enhancement, Disease, Virology, Cancer research and Internal medicine. His Genetic enhancement study incorporates themes from Vector, Immune system, Transduction, Antibody and In vivo. The concepts of his Immune system study are interwoven with issues in Bilirubin, Virus, Adeno-associated virus and Pharmacology.

His studies in Adeno-associated virus integrate themes in fields like In vitro, Neutralizing antibody, Immunology, Immunity and Hepatocellular carcinoma. His Disease research is multidisciplinary, incorporating elements of Ophthalmology, Cataracts, Viral vector and Immune tolerance. The Virology study combines topics in areas such as Cytotoxic T cell, Innate immune system, Glycogen storage disease and Transgene.

Between 2015 and 2021, his most popular works were:

  • Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial (231 citations)
  • Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy. (101 citations)
  • Human Immune Responses to Adeno-Associated Virus (AAV) Vectors. (26 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Enzyme

The scientist’s investigation covers issues in Genetic enhancement, Vector, Virus, Immunogenicity and Internal medicine. Federico Mingozzi has researched Genetic enhancement in several fields, including Bioinformatics, Immunosuppression, Muscular dystrophy, Duchenne muscular dystrophy and Disease. His work carried out in the field of Vector brings together such families of science as Epitope, Cytotoxic T cell, Innate immune system and Neuromuscular disease.

Federico Mingozzi has included themes like Adeno-associated virus, Immune system and Antigen in his Virus study. Immune system is a primary field of his research addressed under Immunology. Federico Mingozzi interconnects Cancer research, Computational biology and Gene delivery in the investigation of issues within Immunogenicity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

Albert M. Maguire;Francesca Simonelli;Eric A. Pierce;Edward N. Pugh.
The New England Journal of Medicine (2008)

2375 Citations

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Manno Cs;Pierce Gf;Arruda Vr;Glader B.
Nature Medicine (2006)

2122 Citations

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

Amit C. Nathwani;Edward G.D. Tuddenham;Savita Rangarajan;Cecilia Rosales.
The New England Journal of Medicine (2011)

1861 Citations

Long-term safety and efficacy of factor IX gene therapy in hemophilia B

Amit C Nathwani;Ulreke M Reiss;Edward G D Tuddenham;Cecilia Rosales;Cecilia Rosales.
The New England Journal of Medicine (2014)

1107 Citations

Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges

Federico Mingozzi;Katherine A. High;Katherine A. High.
Nature Reviews Genetics (2011)

1097 Citations

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Albert M. Maguire;Albert M. Maguire;Katherine A. High;Katherine A. High;Alberto Auricchio;J. Fraser Wright;J. Fraser Wright.
The Lancet (2009)

938 Citations

Immune responses to AAV vectors: overcoming barriers to successful gene therapy

Federico Mingozzi;Katherine A. High;Katherine A. High;Katherine A. High.
Blood (2013)

832 Citations

CD8(+) T-cell responses to adeno-associated virus capsid in humans.

Federico Mingozzi;Marcela V Maus;Marcela V Maus;Daniel J Hui;Denise E Sabatino.
Nature Medicine (2007)

703 Citations

Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.

Francesca Simonelli;Albert M Maguire;Albert M Maguire;Francesco Testa;Eric A Pierce.
Molecular Therapy (2010)

657 Citations

Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer

Federico Mingozzi;Yi-Lin Liu;Eric Dobrzynski;Antje Kaufhold.
Journal of Clinical Investigation (2003)

546 Citations

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