H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 42 Citations 5,691 134 World Ranking 3437 National Ranking 1600

Overview

What is she best known for?

The fields of study she is best known for:

  • Virus
  • Immune system
  • Disease

Her primary areas of study are Epitope, Immunology, Immunogenicity, T cell and Virology. Her work deals with themes such as Computational biology, Major histocompatibility complex and Vaccination, which intersect with Epitope. Her studies in Antigen, Immune system, Human leukocyte antigen, Antibody and FOXP3 are all subfields of Immunology research.

Her work carried out in the field of Immunogenicity brings together such families of science as In silico, Pharmacology and In vivo. Anne S. De Groot studies Regulatory T cell which is a part of T cell. Anne S. De Groot interconnects ELISPOT and Microbiology in the investigation of issues within Virology.

Her most cited work include:

  • Immunogenicity of protein therapeutics (369 citations)
  • Activation of natural regulatory T cells by IgG Fc–derived peptide “Tregitopes” (349 citations)
  • T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation. (167 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Epitope, Virology, Immunology, T cell and Immune system. Her Epitope research incorporates themes from Human leukocyte antigen, Major histocompatibility complex and Immunogenicity. Her Immunogenicity research incorporates elements of In silico and Monoclonal antibody.

The study incorporates disciplines such as Antibody and Immunity in addition to Virology. Her biological study deals with issues like CD8, which deal with fields such as Cytotoxic T cell. In her study, Genomics and Computational immunology is inextricably linked to Computational biology, which falls within the broad field of Immune system.

She most often published in these fields:

  • Epitope (67.97%)
  • Virology (46.75%)
  • Immunology (39.39%)

What were the highlights of her more recent work (between 2018-2021)?

  • Epitope (67.97%)
  • T cell (30.74%)
  • Virology (46.75%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Epitope, T cell, Virology, Immune system and Immunogenicity. Immunology covers Anne S. De Groot research in Epitope. Her research investigates the connection between T cell and topics such as Antibody that intersect with problems in Bioinformatics, T cell immunity, Viral vector, Drug and Inflammation.

Her Virology research is multidisciplinary, incorporating elements of DNA vaccination and Severe acute respiratory syndrome coronavirus 2. In Immune system, she works on issues like Cytotoxic T cell, which are connected to Plasmodium falciparum and Cold-shock domain. The concepts of her Immunogenicity study are interwoven with issues in Computational biology, B cell and Intensive care medicine.

Between 2018 and 2021, her most popular works were:

  • Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools. (19 citations)
  • Highly conserved influenza T cell epitopes induce broadly protective immunity. (12 citations)
  • Therapeutic administration of Tregitope-Human Albumin Fusion with Insulin Peptides to promote Antigen-Specific Adaptive Tolerance Induction. (10 citations)

In her most recent research, the most cited papers focused on:

  • Virus
  • Immune system
  • Disease

Her main research concerns Epitope, T cell, Virology, Immune system and Human leukocyte antigen. Anne S. De Groot has included themes like Regulatory T cell, Immunoglobulin G, Autoimmune disease and Immunogenicity in her Epitope study. Her studies deal with areas such as Infectious disease, Drug, Viral vector and Bioinformatics as well as Immunogenicity.

Her T cell research is included under the broader classification of Immunology. Her Virology research integrates issues from Heterologous, DNA vaccination and Antigen. Her research integrates issues of Whooping cough, Major histocompatibility complex and In silico in her study of Human leukocyte antigen.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Immunogenicity of protein therapeutics

Anne S. De Groot;David W. Scott.
Trends in Immunology (2007)

500 Citations

Activation of natural regulatory T cells by IgG Fc–derived peptide “Tregitopes”

Anne S. De Groot;Leonard Moise;Julie A. McMurry;Erik Wambre.
Blood (2008)

385 Citations

Immuno‐informatics: Mining genomes for vaccine components

Anne S De Groot;Hakima Sbai;Caitlin Saint Aubin;Julie McMurry.
Immunology and Cell Biology (2002)

230 Citations

From genome to vaccine: in silico predictions, ex vivo verification.

Anne S. De Groot;Andrew Bosma;Natasha Chinai;Julie Frost.
Vaccine (2001)

225 Citations

Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics.

Anne S. De Groot;William Martin.
Clinical Immunology (2009)

210 Citations

T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation.

Vibha Jawa;Leslie P. Cousens;Michael Awwad;Eric Wakshull.
Clinical Immunology (2013)

206 Citations

Immunomics: discovering new targets for vaccines and therapeutics

Anne S. De Groot.
Drug Discovery Today (2006)

182 Citations

Emerging Vaccine Informatics

Yongqun He;Rino Rappuoli;Anne S. De Groot;Robert T. Chen.
BioMed Research International (2010)

140 Citations

From genome to vaccine--new immunoinformatics tools for vaccine design.

Anne S. De Groot;Jay A. Berzofsky.
Methods (2004)

132 Citations

Tregitope update: Mechanism of action parallels IVIg

Leslie P. Cousens;Ryan Tassone;Bruce D. Mazer;Vasanthi Ramachandiran.
Autoimmunity Reviews (2013)

130 Citations

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