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Immunology

D-Index
55
Citations
10453
World Ranking
3812
National Ranking
1747

Overview

Anne S. De Groot is affiliated with the University of Georgia in the United States. Their research primarily focuses on medicine, with significant contributions in the fields of immunology and microbiology.

The scientist's work spans several subfields, including immunology, molecular biology, epidemiology, infectious diseases, and radiology, nuclear medicine, and imaging. Their research topics cover diverse areas such as vaccines and immunoinformatics approaches, monoclonal and polyclonal antibodies research, immunotherapy and immune responses, animal virus infections studies, biosimilars and bioanalytical methods, SARS-CoV-2 and COVID-19 research, and influenza virus research studies.

Anne S. De Groot has published in a variety of scientific venues. Frequent publication sources include:

  • Frontiers in Immunology
  • Human Vaccines & Immunotherapeutics
  • Vaccines
  • AASV Annual Meeting
  • Expert Review of Vaccines

Their recent notable papers feature the following:

  • "Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools," 2020, Frontiers in Immunology
  • "T-Cell Dependent Immunogenicity of Protein Therapeutics Pre-clinical Assessment and Mitigation-Updated Consensus and Review 2020," 2020, Frontiers in Immunology
  • "Immunogenicity risk assessment of synthetic peptide drugs and their impurities," 2023, Drug Discovery Today
  • "Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapy," 2021, Expert Review of Vaccines
  • "Highly conserved, non-human-like, and cross-reactive SARS-CoV-2 T cell epitopes for COVID-19 vaccine design and validation," 2021, npj Vaccines

The scientist has collaborated frequently with several researchers, including:

  • William Martin
  • Leonard Moise
  • Andrés H. Gutiérrez
  • Frances Terry
  • Guilhem Richard

Best Publications

  • Immunogenicity of protein therapeutics

    Anne S. De Groot;David W. Scott

  • Activation of natural regulatory T cells by IgG Fc–derived peptide “Tregitopes”

    Anne S. De Groot;Leonard Moise;Julie A. McMurry;Erik Wambre

  • T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation.

    Vibha Jawa;Leslie P. Cousens;Michael Awwad;Eric Wakshull

  • From genome to vaccine: in silico predictions, ex vivo verification.

    Anne S. De Groot;Andrew Bosma;Natasha Chinai;Julie Frost

  • Immuno‐informatics: Mining genomes for vaccine components

    Anne S De Groot;Hakima Sbai;Caitlin Saint Aubin;Julie McMurry

  • Reducing risk, improving outcomes: bioengineering less immunogenic protein therapeutics.

    Anne S. De Groot;William Martin

  • Two novel T cell epitope prediction algorithms based on MHC-binding motifs; comparison of predicted and published epitopes from Mycobacterium tuberculosis and HIV protein sequences.

    G. E. Meister;C. G. P. Roberts;J. A. Berzofsky;A. S. De Groot

  • Immunomics: discovering new targets for vaccines and therapeutics

    Anne S. De Groot

  • Emerging Vaccine Informatics

    Yongqun He;Rino Rappuoli;Anne S. De Groot;Robert T. Chen

  • De-immunization of therapeutic proteins by T-cell epitope modification.

    A S De Groot;P M Knopp;W Martin

  • Clinical validation of the "in silico" prediction of immunogenicity of a human recombinant therapeutic protein.

    E. Koren;A.S. De Groot;V. Jawa;K.D. Beck

  • T cell epitope: friend or foe? Immunogenicity of biologics in context.

    Constanze A. Weber;Preema J. Mehta;Matt Ardito;Lenny Moise

  • Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.

    Anne S De Groot;Leonard Moise;Frances Terry;Andres H Gutierrez

  • Prediction of well-conserved HIV-1 ligands using a matrix-based algorithm, EpiMatrix.

    J. R. A. Schafer;B. M. Jesdale;J. A. George;N. M. Kouttab

  • Tregitope update: Mechanism of action parallels IVIg

    Leslie P. Cousens;Ryan Tassone;Bruce D. Mazer;Vasanthi Ramachandiran

  • From genome to vaccine--new immunoinformatics tools for vaccine design.

    Anne S. De Groot;Jay A. Berzofsky

  • Prediction of immunogenicity for therapeutic proteins: state of the art.

    Anne S De Groot;Leonard Moise

  • In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

    Leslie P. Cousens;Nader Najafian;Federico Mingozzi;Wassim Elyaman

  • An Interactive Web Site Providing Major Histocompatibility Ligand Predictions: Application to HIV Research

    Anne S. De Groot;Bill M. Jesdale;Evan Szu;James R. Schafer

  • Immunoinformatic comparison of T-cell epitopes contained in novel swine-origin influenza A (H1N1) virus with epitopes in 2008–2009 conventional influenza vaccine

    Anne S. De Groot;Matt Ardito;Elizabeth M. McClaine;Leonard Moise

  • Prediction of immunogenicity: in silico paradigms, ex vivo and in vivo correlates.

    Anne S De Groot;Anne S De Groot;Julie McMurry;Lenny Moise

Frequent Co-Authors

William J. Martin
William J. Martin National Institutes of Health
David W. Scott
David W. Scott Uniformed Services University of the Health Sciences
Federico Mingozzi
Federico Mingozzi Children's Hospital of Philadelphia
Ted M. Ross
Ted M. Ross University of Georgia
Søren Buus
Søren Buus University of Copenhagen
Mark C. Poznansky
Mark C. Poznansky Harvard University
Samia J. Khoury
Samia J. Khoury American University of Beirut
David B. Weiner
David B. Weiner The Wistar Institute
Nader Najafian
Nader Najafian Brigham and Women's Hospital
Kenneth H. Mayer
Kenneth H. Mayer Harvard Medical School

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