D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 16,027 175 World Ranking 5781 National Ranking 448

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

In silico, Epitope, Computational biology, Genetics and Major histocompatibility complex are his primary areas of study. His work carried out in the field of In silico brings together such families of science as Decision tree, Immunology, Antigen and K nearest neighbour. His Epitope research includes elements of T cell, Protein folding, Molecular biology, Endoplasmic reticulum and MHC class I.

Darren R. Flower works mostly in the field of Computational biology, limiting it down to topics relating to Bioinformatics and, in certain cases, Microbial genomics, Codon optimization, Reverse vaccinology and Epitope mapping, as a part of the same area of interest. In the field of Genetics, his study on Sequence analysis and PROSITE overlaps with subjects such as InterPro. He focuses mostly in the field of Major histocompatibility complex, narrowing it down to matters related to Stereochemistry and, in some cases, Peptide and Hydrophobic effect.

His most cited work include:

  • The lipocalin protein family: structure and function (1401 citations)
  • VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines (737 citations)
  • The lipocalin protein family: structural and sequence overview. (690 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Computational biology, Epitope, Major histocompatibility complex, In silico and Peptide binding. His biological study spans a wide range of topics, including Plasma protein binding, G protein-coupled receptor, Data mining, Bioinformatics and Peptide sequence. In his research, Protein family is intimately related to Protein structure, which falls under the overarching field of Peptide sequence.

Darren R. Flower combines subjects such as T cell, Immunogenicity and Virology with his study of Epitope. Major histocompatibility complex is the subject of his research, which falls under Genetics. The concepts of his Peptide binding study are interwoven with issues in MHC class I and MHC class II.

He most often published in these fields:

  • Computational biology (38.87%)
  • Epitope (31.17%)
  • Major histocompatibility complex (24.70%)

What were the highlights of his more recent work (between 2011-2020)?

  • Epitope (31.17%)
  • Computational biology (38.87%)
  • In silico (18.22%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Epitope, Computational biology, In silico, Virology and Antigen. His Epitope study is associated with Immunology. The study incorporates disciplines such as Proteome, Bioinformatics, Identification and Peptide binding, Major histocompatibility complex in addition to Computational biology.

His studies examine the connections between Major histocompatibility complex and genetics, as well as such issues in Reverse vaccinology, with regards to Smallpox. In his study, which falls under the umbrella issue of Virology, Cytotoxic T cell, Human genome and Conserved sequence is strongly linked to T cell. His biological study spans a wide range of topics, including Pathogen and Gene.

Between 2011 and 2020, his most popular works were:

  • AllerTOP v.2—a server for in silico prediction of allergens (185 citations)
  • AllerTOP - a server for in silico prediction of allergens (109 citations)
  • Selection of conserved epitopes from hepatitis C virus for pan-populational stimulation of T-cell responses (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His primary areas of study are Epitope, Virology, In silico, Computational biology and Immunology. His work on Epitope is being expanded to include thematically relevant topics such as Human leukocyte antigen. His study in Virology is interdisciplinary in nature, drawing from both CD8 and Antigen.

Darren R. Flower merges many fields, such as In silico and DNA microarray, in his writings. His Computational biology research includes themes of Dosing Frequency, Protective immunity, Immunogenicity and Bioinformatics. As a member of one scientific family, Darren R. Flower mostly works in the field of Peptide, focusing on Amino acid and, on occasion, Peptide sequence.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The lipocalin protein family: structure and function

Darren R. Flower.
Biochemical Journal (1996)

2224 Citations

The lipocalin protein family: structural and sequence overview.

Darren R. Flower;Anthony C.T. North;Clare E. Sansom.
Biochimica et Biophysica Acta (2000)

1073 Citations

VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines

Irini A Doytchinova;Darren R Flower.
BMC Bioinformatics (2007)

916 Citations

Bovine β-lactoglobulin at 1.8 Å resolution — still an enigmatic lipocalin

Sharon Brownlow;João H. Morais Cabral;Ron Cooper;Darren R. Flower.
Structure (1997)

822 Citations

PRINTS and its automatic supplement, prePRINTS

Terri K. Attwood;Paul Bradley;Darren R. Flower;Anna Gaulton.
Nucleic Acids Research (2003)

517 Citations

Pheromone binding to two rodent urinary proteins revealed by X-ray crystallography.

Zsolt Böcskei;Colin R. Groom;Darren R. Flower;Darren R. Flower;Charles E. Wright.
Nature (1992)

439 Citations

Structure and sequence relationships in the lipocalins and related proteins.

Darren R. Flower;Anthony C.T. North;Teresa K. Attwood.
Protein Science (1993)

414 Citations

ON THE PROPERTIES OF BIT STRING-BASED MEASURES OF CHEMICAL SIMILARITY

Darren R. Flower.
Journal of Chemical Information and Computer Sciences (1998)

409 Citations

Modelling G-protein-coupled receptors for drug design.

Darren R Flower.
Biochimica et Biophysica Acta (1999)

393 Citations

Benchmarking B cell epitope prediction: underperformance of existing methods.

Martin J. Blythe;Darren R. Flower.
Protein Science (2009)

393 Citations

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