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Neuroscience

D-Index
44
Citations
7738
World Ranking
7156
National Ranking
420

Overview

Carolyn W. Harley is affiliated with Memorial University of Newfoundland in Canada. Their research has contributed to the field of Neuroscience, with a focus on several related subfields including Cellular and Molecular Neuroscience, Cognitive Neuroscience, Physiology, Molecular Biology, and Sensory Systems.

The research topics covered by Carolyn W. Harley emphasize Neuroscience and Neuropharmacology Research, Neural dynamics and brain function, Photoreceptor and optogenetics research, Alzheimer's disease research and treatments, Memory and Neural Mechanisms, Receptor Mechanisms and Signaling, and Olfactory and Sensory Function Studies.

Among recent papers authored or co-authored by Carolyn W. Harley are:

  • The 'a, b, c's of pretangle tau and their relation to aging and the risk of Alzheimer's Disease, 2021, Seminars in Cell and Developmental Biology
  • Locus Coeruleus Optogenetic Modulation: Lessons Learned from Temporal Patterns, 2021, Brain Sciences

Other notable publications from their recent co-authors include:

  • Locus coeruleus: a new look at the blue spot, 2020, Nature reviews. Neuroscience
  • Novelty-like activation of locus coeruleus protects against deleterious human pretangle tau effects while stress-inducing activation worsens its effects, 2021, Alzheimer s & Dementia Translational Research & Clinical Interventions
  • Locus Coeruleus Activation Patterns Differentially Modulate Odor Discrimination Learning and Odor Valence in Rats, 2021, Cerebral Cortex Communications

Frequent co-authors collaborating with Carolyn W. Harley include:

  • Qi Yuan
  • Tamunotonye Omoluabi
  • Abhinaba Ghosh
  • Kyron D. Power
  • Camila Reinhardt

Publications involving Carolyn W. Harley often appear in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuromodulation Technology at the Neural Interface
  • Nature reviews. Neuroscience
  • Alzheimer s & Dementia Translational Research & Clinical Interventions
  • Cerebral Cortex Communications

The research output demonstrates a strong engagement with cellular mechanisms underlying neurological conditions, neural modulation via optogenetics, and the aging-related risks associated with Alzheimer's Disease. This contribution spans multiple venues and collaborative efforts within the neuroscience community.

Best Publications

  • Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory.

    Mara Mather;David Clewett;Michiko Sakaki;Carolyn W. Harley

  • Locus coeruleus: a new look at the blue spot.

    Gina R. Poe;Stephen Foote;Oxana Eschenko;Joshua P. Johansen

  • The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain.

    Mara Mather;Carolyn W. Harley

  • MK-801 and AP5 impair acquisition, but not retention, of the Morris milk maze.

    Vincent Heale;Carolyn Harley

  • Long-lasting potentiation of the dentate gyrus population spike by norepinephrine

    R.S. Neuman;C.W. Harley

  • A role for norepinephrine in arousal, emotion and learning?: limbic modulation by norepinephrine and the Kety hypothesis.

    Carolyn W. Harley

  • Norepinephrine and the dentate gyrus.

    Carolyn W Harley

  • NOVELTY-ELICITED, NORADRENALINE-DEPENDENT ENHANCEMENT OF EXCITABILITY IN THE DENTATE GYRUS

    Valentina Kitchigina;Andrey Vankov;Carolyn Harley;Susan J. Sara

  • Noradrenergic and locus coeruleus modulation of the perforant path-evoked potential in rat dentate gyrus supports a role for the locus coeruleus in attentional and memorial processes

    Harley C

  • The action of norepinephrine in the dentate gyrus: beta-mediated facilitation of evoked potentials in vitro.

    Jean-Claude Lacaille;Carolyn W. Harley

  • Locus ceruleus activation initiates delayed synaptic potentiation of perforant path input to the dentate gyrus in awake rats: a novel beta-adrenergic- and protein synthesis-dependent mammalian plasticity mechanism.

    Susan G Walling;Carolyn W Harley

  • Norepinephrine and Dopamine as Learning Signals

    Carolyn W. Harley

  • Locus Ceruleus Activation Suppresses Feedforward Interneurons and Reduces β-γ Electroencephalogram Frequencies While It Enhances θ Frequencies in Rat Dentate Gyrus

    Robert A. M. Brown;Susan G. Walling;J. Steve Milway;Carolyn W. Harley

  • Mitral Cell β1 and 5-HT2A Receptor Colocalization and cAMP Coregulation: A New Model of Norepinephrine-Induced Learning in the Olfactory Bulb

    Qi Yuan;Carolyn W. Harley;John H. McLean

  • Orexin-A infusion in the locus ceruleus triggers norepinephrine (NE) release and NE-induced long-term potentiation in the dentate gyrus.

    Susan G. Walling;David J. Nutt;Margaret D. Lalies;Carolyn W. Harley

  • Ibotenate lesions of the hippocampus enhance latent inhibition in conditioned taste aversion and increase resistance to extinction in conditioned taste preference.

    Steve Reilly;Carolyn W. Harley;Sam Revusky

  • Isoproterenol increases CREB phosphorylation and olfactory nerve-evoked potentials in normal and 5-HT-depleted olfactory bulbs in rat pups only at doses that produce odor preference learning.

    Qi Yuan;Carolyn W. Harley;Jamie C. Bruce;Andrea Darby-King

  • Glutamate ejection in the locus coeruleus enhances the perforant path-evoked population spike in the dentate gyrus.

    C. W. Harley;J. S. Milway

  • pCREB in the neonate rat olfactory bulb is selectively and transiently increased by odor preference-conditioned training.

    John H. McLean;Carolyn W. Harley;Andrea Darby-King;Qi Yuan

  • Testosterone decreases CA1 plasticity in vivo in gonadectomized male rats.

    C.W. Harley;C.W. Malsbury;A. Squires;R.A.M. Brown

Frequent Co-Authors

Mara Mather
Mara Mather University of Southern California
Dale Corbett
Dale Corbett University of Ottawa
Thomas Knöpfel
Thomas Knöpfel Hong Kong Baptist University
Susan J. Sara
Susan J. Sara Collège de France
Benjamin Rusak
Benjamin Rusak Dalhousie University
J. John Mann
J. John Mann Columbia University
D. Caroline Blanchard
D. Caroline Blanchard University of Hawaii at Manoa
Robert J. Blanchard
Robert J. Blanchard University of Hawaii at Manoa
Steven M. Silverstein
Steven M. Silverstein University of Rochester Medical Center
Rachael L. Neve
Rachael L. Neve Harvard University

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