Jouni Sirviö

Overview

Best Publications

• Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein

  Merja Lakso;Suvi Vartiainen;Anu Maarit Moilanen;Jouni Sirviö

  485
  Citations

• The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus.

  Eero Castrén;Mervi Pitkänen;Jouni Sirviö;Alexander Parsadanian

  394
  Citations

• Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task.

  T Puumala;J Sirviö

  294
  Citations

• Guanfacine, But Not Clonidine, Improves Planning and Working Memory Performance in Humans

  Pekka Jäkälä;Minna Riekkinen;Jouni Sirviö;Esa Koivisto

  254
  Citations

• Behavioral and pharmacological studies on the validation of a new animal model for attention deficit hyperactivity disorder.

  Tarja Puumala;Sirja Ruotsalainen;Pekka Jäkälä;Esa Koivisto

  161
  Citations

• Experimental studies on the role of serotonin in cognition

  Jouni Sirviö;Paavo Riekkinen;Pekka Jäkälä;Paavo J. Riekkinen

  151
  Citations

• α2-Adrenergic drug effects on brain monoamines, locomotion, and body temperature are largely abolished in mice lacking the α2A-adrenoceptor subtype

  Janne Lähdesmäki;Jukka Sallinen;Ewen MacDonald;Jouni Sirviö

  144
  Citations

• An α2-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats

  K Puurunen;J Jolkkonen;J Sirviö;A Haapalinna

  142
  Citations

• Pharmacological Properties, Central Nervous System Effects, and Potential Therapeutic Applications of Atipamezole, a Selective α2‐Adrenoceptor Antagonist

  Antti Pertovaara;Antti Haapalinna;Jouni Sirviö;Raimo Virtanen

  138
  Citations

• Pharmacological characterization and CNS effects of a novel highly selective α2C‐adrenoceptor antagonist JP‐1302

  Sallinen J;Höglund I;Engström M;Lehtimäki J

  136
  Citations

• Effects of concurrent manipulations of nicotinic and muscarinic receptors on spatial and passive avoidance learning

  Paavo Riekkinen;Jouni Sirviö;Minna Aaltonen

  134
  Citations

• Neocortical, hippocampal and septal parvalbumin- and somatostatin-containing neurons in young and aged rats: correlation with passive avoidance and water maze performance.

  R. Miettinen;J. Sirviö;P. Riekkinen;M.P. Laakso

  131
  Citations

• Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons have impaired long-term spatial memory but normal hippocampal LTP.

  Tommi Saarelainen;Raimo Pussinen;Eija Koponen;Leena Alhonen

  129
  Citations

• Central alpha1-adrenoceptors: their role in the modulation of attention and memory formation.

  Jouni Sirviö;Ewen MacDonald

  127
  Citations

• The effects of p-chlorophenylalanine-induced serotinin synthesis inhibition and muscarinic blockade on the performance of rats in a 5-choice serial reaction time task

  Pekka Jäkälä;Jouni Sirviö;Jukka Jolkkonen;Paavo Riekkinen

  125
  Citations

• Activation of 5-HT2A receptors impairs response control of rats in a five-choice serial reaction time task

  Tiina Koskinen;Sirja Ruotsalainen;Tarja Puumala;Raimo Lappalainen

  124
  Citations

• Interaction between raphe dorsalis and nucleus basalis magnocellularis in spatial learning.

  Paavo Riekkinen;Jouni Sirvio

  119
  Citations

• Guanfacine and Clonidine, Alpha2-Agonists, Improve Paired Associates Learning, but not Delayed Matching to Sample, in Humans

  Pekka Jäkälä;Jouni Sirviö;Minna Riekkinen;Esa Koivisto

  115
  Citations

• Pharmacological consequences of cholinergic plus serotonergic manipulations.

  Paavo Riekkinen;Jouni Sirviö;Antti Valjakka;Riitta Miettinen

  112
  Citations

• Similar memory impairments found in medial septal-vertical diagonal band of Broca and nucleus basalis lesioned rats: are memory defects induced by nucleus basalis lesions related to the degree of non-specific subcortical cell loss?

  Paavo Riekkinen;Jouni Sirviö

  111
  Citations