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Lisa E. Kalynchuk

Lisa E. Kalynchuk

D-Index & Metrics

Neuroscience

D-Index
32
Citations
4683
World Ranking
9518
National Ranking
552

Overview

Lisa E. Kalynchuk is affiliated with the University of Victoria in Canada and has a research focus primarily in the field of Neuroscience. Their work spans several subfields including Behavioral Neuroscience, Biological Psychiatry, Developmental Neuroscience, Physiology, and Molecular Biology.

The scientist's research topics cover a range of areas within neuroscience, notably Stress Responses and Cortisol, Tryptophan and brain disorders, Neurogenesis and neuroplasticity mechanisms, Diet and metabolism studies, Genetics and Neurodevelopmental Disorders, Neuroendocrine regulation and behavior, and Neuroscience and Neuropharmacology Research.

Kalynchuk has contributed to multiple frequent publication venues. These include:

  • Biological Psychiatry
  • SSRN Electronic Journal
  • Frontiers in Pharmacology
  • Chronic Stress
  • Mitochondrion

Their recent papers demonstrate a focus on the pathophysiological mechanisms and therapeutic perspectives related to stress, depression, and neuropsychiatric disorders. Notable publications include:

  • "Severe life stress, mitochondrial dysfunction, and depressive behavior: A pathophysiological and therapeutic perspective" (2020) in Mitochondrion
  • "Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: A long and winding road" (2021) in Drug Discovery Today
  • "Fast-acting antidepressant-like effects of Reelin evaluated in the repeated-corticosterone chronic stress paradigm" (2020) in Neuropsychopharmacology
  • "The Role of MeCP2 in Regulating Synaptic Plasticity in the Context of Stress and Depression" (2022) in Cells
  • "Ketamine Rescues Hippocampal Reelin Expression and Synaptic Markers in the Repeated-Corticosterone Chronic Stress Paradigm" (2020) in Frontiers in Pharmacology

The scientist has worked frequently with several co-authors. These include Héctor J. Caruncho, Jenessa N. Johnston, Carla L. Sánchez-Lafuente, Josh Allen, and Brady S. Reive. Collaborative research with these colleagues reflects an interdisciplinary approach within neuroscience and psychiatric research domains.

Best Publications

  • Effect of repeated corticosterone injections and restraint stress on anxiety and depression-like behavior in male rats.

    Andrea Gregus;Amanda J. Wintink;Alicia C. Davis;Lisa E. Kalynchuk

  • Effect of different doses of corticosterone on depression-like behavior and HPA axis responses to a novel stressor

    Sarah A. Johnson;Neil M. Fournier;Lisa E. Kalynchuk

  • Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression.

    Josh Allen;Raquel Romay-Tallon;Kyle J. Brymer;Hector J. Caruncho

  • Postnatal Inflammation Increases Seizure Susceptibility in Adult Rats

    Michael A. Galic;Kiarash Riazi;James G. Heida;Abdeslam Mouihate

  • Behavioral and neurobiological consequences of prolonged glucocorticoid exposure in rats: relevance to depression

    Erin Y. Sterner;Lisa E. Kalynchuk

  • Corticosterone increases depression-like behavior, with some effects on predator odor-induced defensive behavior, in male and female rats.

    Lisa E. Kalynchuk;Andrea Gregus;Daniel Boudreau;Tara S. Perrot-Sinal

  • Long-term amygdala kindling in rats as a model for the study of interictal emotionality in temporal lobe epilepsy.

    L.E Kalynchuk

  • Repeated exposure to corticosterone increases depression-like behavior in two different versions of the forced swim test without altering nonspecific locomotor activity or muscle strength.

    Wendie Marks;Neil M. Fournier;Lisa E. Kalynchuk

  • Changes in emotional behavior produced by long-term amygdala kindling in rats

    Lisa E. Kalynchuk;John P.J. Pinel;Dallas Treit;Tod E. Kippin

  • The progressive development of depression-like behavior in corticosterone-treated rats is paralleled by slowed granule cell maturation and decreased reelin expression in the adult dentate gyrus

    April L. Lussier;Katherina Lebedeva;Erin Y. Fenton;Axel Guskjolen

  • Repeated exposure to corticosterone, but not restraint, decreases the number of reelin-positive cells in the adult rat hippocampus.

    April L. Lussier;Hector J. Caruncho;Lisa E. Kalynchuk

  • Persistence of the interictal emotionality produced by long-term amygdala kindling in rats

    L.E. Kalynchuk;J.P.J. Pinel;D. Treitj;S.J. Barnes

  • Object-recognition and spatial learning and memory in rats prenatally exposed to ethanol.

    C. Kwon Kim;Lisa E. Kalynchuk;Tom J. Kornecook;David G. Mumby

  • Imipramine protects against the deleterious effects of chronic corticosterone on depression-like behavior, hippocampal reelin expression, and neuronal maturation.

    Erin Y. Fenton;Neil M. Fournier;April L. Lussier;Raquel Romay-Tallon

  • Long-term kindling and interictal emotionality in rats: effect of stimulation site.

    Lisa E Kalynchuk;John P.J Pinel;Dallas Treit

  • Reelin as a putative vulnerability factor for depression: examining the depressogenic effects of repeated corticosterone in heterozygous reeler mice.

    April L. Lussier;Raquel Romay-Tallón;Lisa E. Kalynchuk;Hector J. Caruncho

  • Sex and repeated restraint stress interact to affect cat odor-induced defensive behavior in adult rats.

    Tara S. Perrot-Sinal;Andrea Gregus;Daniel Boudreau;Lisa E. Kalynchuk

  • Altered GABAergic and glutamatergic activity within the rat hippocampus and amygdala in rats subjected to repeated corticosterone administration but not restraint stress

    A.L. Lussier;R. Romay-Tallón;H.J. Caruncho;L.E. Kalynchuk

  • Kindling-induced emotional behavior in male and female rats.

    Amanda J Wintink;Nicole A Young;Alicia C Davis;Andrea Gregus

  • Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: A long and winding road.

    Bashkim Kadriu;Laura Musazzi;Jenessa N. Johnston;Lisa E. Kalynchuk

  • Severe life stress, mitochondrial dysfunction, and depressive behavior: A pathophysiological and therapeutic perspective.

    Josh Allen;Hector J. Caruncho;Lisa E. Kalynchuk

  • Postnatal inflammation increases seizure susceptibility in adult rats

    M Galic;K Riazi;J Heida;A Mouihate

Frequent Co-Authors

John P. J. Pinel
John P. J. Pinel University of British Columbia
Dallas Treit
Dallas Treit University of Alberta
Quentin J. Pittman
Quentin J. Pittman University of Calgary
Sarah J. Spencer
Sarah J. Spencer RMIT University
Laura Musazzi
Laura Musazzi University of Milano-Bicocca
Satyabrata Kar
Satyabrata Kar University of Alberta
Maurizio Popoli
Maurizio Popoli University of Milan
Joanne Weinberg
Joanne Weinberg University of British Columbia
Michael A. Persinger
Michael A. Persinger Laurentian University

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