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Pierre-Pascal Lenck-Santini

Pierre-Pascal Lenck-Santini

D-Index & Metrics

Neuroscience

D-Index
32
Citations
4255
World Ranking
9526
National Ranking
468

Overview

Pierre-Pascal Lenck-Santini is a researcher affiliated with Inserm in France, specializing in neuroscience. Their body of work primarily focuses on cellular and molecular neuroscience, with additional contributions to cognitive neuroscience, molecular biology, cardiology and cardiovascular medicine, and genetics. The thematic scope of their research covers neuroscience and neuropharmacology, memory and neural mechanisms, ion channel regulation and function, neural dynamics and brain function, cardiac electrophysiology and arrhythmias, photoreceptor and optogenetics research, and genetics and neurodevelopmental disorders.

They have authored several recent publications, including:

  • A knock-in mouse model for KCNQ2-related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment (2020, Epilepsia)
  • Focal Dorsal Hippocampal Nav1.1 Knock Down Alters Place Cell Temporal Coordination and Spatial Behavior (2020, Cerebral Cortex)
  • Time-limited alterations in cortical activity of a knock-in mouse model of KCNQ2-related developmental and epileptic encephalopathy (2022, The Journal of Physiology)
  • Extrinsic control of the early postnatal CA1 hippocampal circuits (2023, Neuron)
  • Alterations of Neuronal Dynamics as a Mechanism for Cognitive Impairment in Epilepsy (2020, Current topics in behavioral neurosciences)

Their frequent co-authors include Mathieu Milh, Najoua Biba, Laurent Villard, Salomé Mortet, and Agnès Baude. Collaboration with these researchers suggests active engagement in multidisciplinary projects within their fields of interest.

The researcher has published primarily in venues such as bioRxiv (Cold Spring Harbor Laboratory), Epilepsia, Cerebral Cortex, The Journal of Physiology, and Neuron. Their most prolific contributions have appeared in bioRxiv.

Best Publications

  • Role of interictal epileptiform abnormalities in cognitive impairment

    Gregory L. Holmes;Pierre-Pascal Lenck-Santini

  • Coding for spatial goals in the prelimbic/infralimbic area of the rat frontal cortex

    V. Hok;E. Save;P. P. Lenck-Santini;B. Poucet

  • Hippocampal interictal epileptiform activity disrupts cognition in humans

    Jonathan K. Kleen;Rod C. Scott;Gregory L. Holmes;David W. Roberts

  • Goal-related activity in hippocampal place cells.

    Vincent Hok;Pierre-Pascal Lenck-Santini;Sébastien Roux;Etienne Save

  • Hippocampal interictal spikes disrupt cognition in rats.

    Jonathan K. Kleen;Rod C. Scott;Rod C. Scott;Gregory L. Holmes;Pierre Pascal Lenck-Santini

  • Attention-Like Modulation of Hippocampus Place Cell Discharge

    André A. Fenton;William W. Lytton;Jeremy M. Barry;Pierre Pascal Lenck-Santini;Pierre Pascal Lenck-Santini;Pierre Pascal Lenck-Santini

  • SCN1A mutations in Dravet syndrome: Impact of interneuron dysfunction on neural networks and cognitive outcome

    Alex C. Bender;Richard P. Morse;Rod C. Scott;Rod C. Scott;Gregory L. Holmes

  • Representation of objects in space by two classes of hippocampal pyramidal cells.

    Bruno Rivard;Yu Li;Pierre-Pascal Lenck-Santini;Bruno Poucet

  • Mechanisms Responsible for Cognitive Impairment in Epilepsy

    Pierre-Pascal Lenck-Santini;Rodney C. Scott

  • Altered phase precession and compression of temporal sequences by place cells in epileptic rats.

    Pierre-Pascal Lenck-Santini;Gregory L. Holmes

  • Relationships between Place Cell Firing Fields and Navigational Decisions by Rats

    Pierre-Pascal Lenck-Santini;Robert U. Muller;Robert U. Muller;Etienne Save;Bruno Poucet

  • Evidence for a Relationship Between Place-Cell Spatial Firing and Spatial Memory Performance

    Pierre-Pascal Lenck-Santini;Etienne Save;Bruno Poucet

  • Spatial navigation and hippocampal place cell firing: the problem of goal encoding.

    B Poucet;P P Lenck-Santini;V Hok;E Save

  • Sensory and memory properties of hippocampal place cells.

    Bruno Poucet;Etienne Save;Pierre-Pascal Lenck-Santini

  • Focal Scn1a knockdown induces cognitive impairment without seizures

    Alex C. Bender;Heather Natola;Christian Ndong;Gregory L. Holmes

  • Study of CA1 place cell activity and exploratory behavior following spatial and nonspatial changes in the environment.

    P P Lenck-Santini;B. Rivard;R U Muller;R U Muller;Bruno Poucet;Bruno Poucet

  • Speed modulation of hippocampal theta frequency correlates with spatial memory performance

    Gregory R. Richard;Ali Titiz;Anna Tyler;Gregory L. Holmes

  • Effect of Interictal Spikes on Single‐Cell Firing Patterns in the Hippocampus

    Jun-Li Zhou;Pierre-Pascal Lenck-Santini;Qian Zhao;Gregory L. Holmes

  • Cognitive and Behavioral Co-Morbidities of Epilepsy

    Jonathan K. Kleen;Rod C. Scott;Pierre-Pascal Lenck-Santini;Gregory L. Holmes

  • Place-cell firing does not depend on the direction of turn in a Y-maze alternation task.

    Pierre-Pascal Lenck-Santini;Etienne Save;Bruno Poucet

Frequent Co-Authors

Rod C. Scott
Rod C. Scott University of Vermont
Gregory L. Holmes
Gregory L. Holmes University of Vermont
Bruno Poucet
Bruno Poucet Aix-Marseille University
Etienne Save
Etienne Save Aix-Marseille University
Barbara C. Jobst
Barbara C. Jobst Dartmouth–Hitchcock Medical Center
André A. Fenton
André A. Fenton New York University
Roustem Khazipov
Roustem Khazipov Kazan Federal University
Lisa E. Kalynchuk
Lisa E. Kalynchuk University of Victoria
William W. Lytton
William W. Lytton SUNY Downstate Medical Center
Liset Menendez de la Prida
Liset Menendez de la Prida Spanish National Research Council

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