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Bridgette D. Semple

Bridgette D. Semple

D-Index & Metrics

Neuroscience

D-Index
38
Citations
7363
World Ranking
8497
National Ranking
254

Overview

Bridgette D. Semple is affiliated with Monash University in Australia, where their research spans the field of medicine with a focus on neurology, epidemiology, molecular biology, pediatrics, perinatology, and child health, as well as psychiatry and mental health.

Their research topics cover a broad spectrum within neurological and brain-related conditions, including:

  • Traumatic Brain Injury and Neurovascular Disturbances
  • Traumatic Brain Injury Research
  • Epilepsy Research and Treatment
  • Neonatal and Fetal Brain Pathology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • S100 Proteins and Annexins
  • Automotive and Human Injury Biomechanics

Bridgette D. Semple has authored multiple papers with notable examples including:

  • "Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation" (2021), published in Journal of Neuroinflammation
  • "Potential Neuroprotective Effect of the HMGB1 Inhibitor Glycyrrhizin in Neurological Disorders" (2020), published in ACS Chemical Neuroscience
  • "Acute treatment with TrkB agonist LM22A-4 confers neuroprotection and preserves myelin integrity in a mouse model of pediatric traumatic brain injury" (2021), published in Experimental Neurology
  • "A systemic immune challenge to model hospital-acquired infections independently regulates immune responses after pediatric traumatic brain injury" (2021), published in Journal of Neuroinflammation
  • "Immune Challenges and Seizures: How Do Early Life Insults Influence Epileptogenesis?" (2020), published in Frontiers in Pharmacology

The frequent co-authors working alongside Bridgette D. Semple include:

  • Terence J. O'Brien
  • Larissa K. Dill
  • Richelle Mychasiuk
  • Sandy R. Shultz
  • Erskine Chu

The scientist's research has been regularly published in several journals, with the most frequent publication venues being:

  • Journal of Neuroinflammation
  • Journal of Neurotrauma
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Experimental Neurology
  • Epilepsia

Best Publications

  • Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species

    Bridgette D. Semple;Klas Blomgren;Klas Blomgren;Kayleen Gimlin;Donna M. Ferriero

  • Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks

    Bridgette D Semple;Thomas K Kossmann;Maria Cristina Morganti-Kossmann

  • Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2−/− mice

    Bridgette D Semple;Nicole Bye;Nicole Bye;Mario Rancan;Jenna M Ziebell

  • Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module

    Roeben Nocon Munji;Allison Luen Soung;Geoffrey Aaron Weiner;Fabien Sohet

  • Inflammation in epileptogenesis after traumatic brain injury.

    Kyria M. Webster;Mujun Sun;Peter Crack;Terence J. O’Brien

  • The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments.

    Maria Cristina Morganti-Kossmann;Bridgette D. Semple;Sarah C. Hellewell;Nicole Bye

  • Progesterone treatment reduces neuroinflammation, oxidative stress and brain damage and improves long-term outcomes in a rat model of repeated mild traumatic brain injury

    Kyria M. Webster;David K. Wright;David K. Wright;Mujun Sun;Bridgette D. Semple

  • Interleukin-1 receptor in seizure susceptibility after traumatic injury to the pediatric brain.

    Bridgette D Semple;Terence J O'Brien;Kayleen Gimlin;David K Wright

  • Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation.

    Erskine Chu;Richelle Mychasiuk;Margaret L Hibbs;Bridgette D Semple;Bridgette D Semple

  • Deficiency of the chemokine receptor CXCR2 attenuates neutrophil infiltration and cortical damage following closed head injury.

    Bridgette D Semple;Bridgette D Semple;Nicole Bye;Nicole Bye;Jenna M Ziebell;M Cristina Morganti-Kossmann;M Cristina Morganti-Kossmann

  • Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems.

    Rishabh Sharma;Sandy R. Shultz;Sandy R. Shultz;Marcus J. Robinson;Antonio Belli

  • Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy.

    Bridgette D. Semple;Bridgette D. Semple;Akram Zamani;Genevieve Rayner;Genevieve Rayner;Sandy R. Shultz;Sandy R. Shultz

  • High mobility group box 1 (HMGB1) as a novel frontier in epileptogenesis: from pathogenesis to therapeutic approaches

    Yam Nath Paudel;Bridgette D Semple;Bridgette D Semple;Nigel C Jones;Nigel C Jones;Iekhsan Othman

  • Social dysfunction after pediatric traumatic brain injury: A translational perspective.

    Nicholas P Ryan;Cathy Catroppa;Cathy Catroppa;Celia Godfrey;Linda J Noble-Haeusslein

  • Therapies negating neuroinflammation after brain trauma.

    Sarah Hellewell;Bridgette D. Semple;Maria Cristina Morganti-Kossmann;Maria Cristina Morganti-Kossmann

  • Found in translation: Understanding the biology and behavior of experimental traumatic brain injury

    Corina O. Bondi;Bridgette D. Semple;Linda J. Noble-Haeusslein;Nicole D. Osier

  • Neutrophil elastase mediates acute pathogenesis and is a determinant of long-term behavioral recovery after traumatic injury to the immature brain.

    Bridgette D. Semple;Bridgette D. Semple;Alpa Trivedi;Kayleen Gimlin;Linda J. Noble-Haeusslein

  • Potential Neuroprotective Effect of the HMGB1 Inhibitor Glycyrrhizin in Neurological Disorders.

    Yam Nath Paudel;Efthalia Angelopoulou;Bridgette Semple;Bridgette Semple;Christina Piperi

  • Deficits in Social Behavior Emerge during Development after Pediatric Traumatic Brain Injury in Mice

    Bridgette D. Semple;Sandra A. Canchola;Linda J. Noble-Haeusslein

  • Neuroinflammation in Post-Traumatic Epilepsy: Pathophysiology and Tractable Therapeutic Targets.

    Rishabh Sharma;Wai Lam Leung;Akram Zamani;Terence J O'Brien

  • Behavioral, blood, and magnetic resonance imaging biomarkers of experimental mild traumatic brain injury

    David K. Wright;David K. Wright;Jack Trezise;Alaa Kamnaksh;Ramsey Bekdash

  • CCL2 modulates cytokine production in cultured mouse astrocytes

    Bridgette D Semple;Tony Frugier;Tony Frugier;M Cristina Morganti-Kossmann

Frequent Co-Authors

Sandy R. Shultz
Sandy R. Shultz Monash University
Nigel C. Jones
Nigel C. Jones Monash University
Richelle Mychasiuk
Richelle Mychasiuk Monash University
Donna M. Ferriero
Donna M. Ferriero University of California, San Francisco
Leigh A. Johnston
Leigh A. Johnston University of Melbourne
Denes V. Agoston
Denes V. Agoston Uniformed Services University of the Health Sciences
Cathy Catroppa
Cathy Catroppa Royal Children's Hospital
Vicki Anderson
Vicki Anderson Murdoch Children's Research Institute
Elisabeth A. Wilde
Elisabeth A. Wilde Baylor College of Medicine
Gerri Hanten
Gerri Hanten Baylor College of Medicine

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