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Amy F.T. Arnsten

Amy F.T. Arnsten

D-Index & Metrics

Neuroscience

D-Index
104
Citations
44405
World Ranking
661
National Ranking
367

Research.com Recognitions

  • 2017 - Member of the National Academy of Medicine (NAM)
  • 2013 - National Institutes of Health Director's Pioneer Award

Overview

Amy F.T. Arnsten is affiliated with Yale University in the United States and has an extensive research portfolio primarily in neuroscience and medicine. Their work spans multiple subfields including cellular and molecular neuroscience, cognitive neuroscience, physiology, molecular biology, and neurology.

The researcher's recent publications cover topics related to Alzheimer's disease, synaptic density, cognitive performance, neuromodulation, and the effects of chronic stress on brain connectivity. Notable papers include:

  • Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease (2020, Alzheimer s & Dementia)
  • In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET (2020, Alzheimer s & Dementia)
  • Neuromodulation of prefrontal cortex cognitive function in primates: the powerful roles of monoamines and acetylcholine (2021, Neuropsychopharmacology)
  • Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB-J (2022, Alzheimer s & Dementia)
  • Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes (2021, Chronic Stress)

Amy F.T. Arnsten collaborates frequently with several coauthors, including:

  • Dibyadeep Datta
  • Anissa Abi-Dargham
  • New York
  • Deanna M. Barch
  • St Louis

Their publications appear most often in the following venues:

  • Biological Psychiatry
  • Alzheimer s & Dementia
  • American Journal of Geriatric Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Aging Neuroscience

The main fields of study for this researcher are:

  • Neuroscience
  • Medicine

Within these fields, the subfields of study include:

  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience
  • Physiology
  • Molecular Biology
  • Neurology

Their main research topics encompass:

  • Neuroscience and Neuropharmacology Research
  • Alzheimer's disease research and treatments
  • Memory and Neural Mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Functional Brain Connectivity Studies
  • Dementia and Cognitive Impairment Research
  • Tryptophan and brain disorders

Awards received by Amy F.T. Arnsten include:

  • Member of the National Academy of Medicine (NAM), 2017
  • National Institutes of Health Director's Pioneer Award, 2013

Best Publications

  • Stress signalling pathways that impair prefrontal cortex structure and function

    Amy F. T. Arnsten

  • Neurobiology of Executive Functions: Catecholamine Influences on Prefrontal Cortical Functions

    Amy F.T. Arnsten;Bao-Ming Li

  • Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory.

    Susheel Vijayraghavan;Min Wang;Shari G Birnbaum;Shari G Birnbaum;Graham V Williams

  • The Neuropsychopharmacology of Fronto-Executive Function: Monoaminergic Modulation

    T.W. Robbins;A.F.T. Arnsten

  • Supranormal Stimulation of D1 Dopamine Receptors in the Rodent Prefrontal Cortex Impairs Spatial Working Memory Performance

    Justin Zahrt;Jane R. Taylor;Rex G. Mathew;Amy F. T. Arnsten

  • Noise Stress Impairs Prefrontal Cortical Cognitive Function in Monkeys: Evidence for a Hyperdopaminergic Mechanism

    Amy F. T. Arnsten;Patricia S. Goldman-Rakic

  • Adrenergic Pharmacology and Cognition: Focus on the Prefrontal Cortex

    Brian P. Ramos;Amy F.T. Arnsten

  • α2A-Adrenoceptors Strengthen Working Memory Networks by Inhibiting cAMP-HCN Channel Signaling in Prefrontal Cortex

    Min Wang;Brian P. Ramos;Constantinos D. Paspalas;Constantinos D. Paspalas;Yousheng Shu

  • Role of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder

    Steven M. Southwick;Steven M. Southwick;J.Douglas Bremner;J.Douglas Bremner;Ann M. Rasmusson;Ann M. Rasmusson;Charles A. Morgan;Charles A. Morgan

  • Catecholamine modulation of prefrontal cortical cognitive function.

    Amy F.T Arnsten

  • Methylphenidate Preferentially Increases Catecholamine Neurotransmission within the Prefrontal Cortex at Low Doses that Enhance Cognitive Function

    Craig W. Berridge;David M. Devilbiss;Matthew E. Andrzejewski;Amy F.T. Arnsten

  • Stress weakens prefrontal networks: molecular insults to higher cognition

    Amy F T Arnsten

  • Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys

    A. F. T. Arnsten;J. X. Cai;B. L. Murphy;P. S. Goldman-Rakic

  • Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.

    B. L. Murphy;A. F. T. Arnsten;P. S. Goldman-Rakic;R. H. Roth

  • Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates

    Amy F. T. Arnsten;Patricia S. Goldman-Rakic

  • Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses.

    Amy F.T. Arnsten;Min J. Wang;Constantinos D. Paspalas

  • The Contribution of α2-Noradrenergic Mechanisms to Prefrontal Cortical Cognitive Function: Potential Significance for Attention-Deficit Hyperactivity Disorder

    Amy F.T. Arnsten;Jenna C. Steere;Robert D. Hunt

  • The Biology of Being Frazzled

    Amy F. T. Arnsten

  • A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder.

    Larry Scahill;Phillip B. Chappell;Young S. Kim;Robert T. Schultz

  • Neurobiological Circuits Regulating Attention, Cognitive Control, Motivation, and Emotion: Disruptions in Neurodevelopmental Psychiatric Disorders

    Amy F.T. Arnsten;Katya Rubia

  • Catecholamine regulation of the prefrontal cortex

    Amy F. T. Arnsten

Frequent Co-Authors

Mika Naganawa
Mika Naganawa Yale University
Nabeel Nabulsi
Nabeel Nabulsi Yale University
Shari G. Birnbaum
Shari G. Birnbaum The University of Texas Southwestern Medical Center
Daeyeol Lee
Daeyeol Lee Johns Hopkins University
Rajita Sinha
Rajita Sinha Yale University
Craig W. Berridge
Craig W. Berridge University of Wisconsin–Madison
Carolyn M. Mazure
Carolyn M. Mazure Yale University

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