Tom H. M. Ottenhoff spends much of his time researching Immunology, Tuberculosis, Mycobacterium tuberculosis, Virology and Immune system. His works in Cytokine, Immunity, Vaccination, Cellular immunity and T cell are all subjects of inquiry into Immunology. His Tuberculosis research is multidisciplinary, relying on both Acquired immune system, Interferon gamma, Internal medicine, Disease and Genetic variation.
Tom H. M. Ottenhoff has included themes like Tuberculin and Case-control study in his Mycobacterium tuberculosis study. His Virology research incorporates themes from Mycobacterium bovis, ESAT-6, Antigen and Microbiology. His research in Immune system intersects with topics in Inflammation and Cytotoxic T cell.
Immunology, Tuberculosis, Mycobacterium tuberculosis, Antigen and Virology are his primary areas of study. His work in Immunology addresses subjects such as Disease, which are connected to disciplines such as Asymptomatic. His studies in Tuberculosis integrate themes in fields like Biomarker, Internal medicine and Vaccination.
His work carried out in the field of Mycobacterium tuberculosis brings together such families of science as Peripheral blood mononuclear cell and Interferon gamma. His Antigen research is multidisciplinary, incorporating elements of Cytotoxic T cell, Mycobacterium leprae and Antibody. His Virology research integrates issues from Mycobacterium bovis, Human leukocyte antigen, Microbiology and Immunogenicity.
Tom H. M. Ottenhoff mostly deals with Tuberculosis, Mycobacterium tuberculosis, Immunology, Antigen and Immune system. His Tuberculosis study integrates concerns from other disciplines, such as Biomarker, Internal medicine, Metabolomics and Transcriptome. His Mycobacterium tuberculosis study combines topics in areas such as Acquired immune system, Pathogen, Microbiology, CD8 and Effector.
His work deals with themes such as Downregulation and upregulation and Disease, which intersect with Immunology. He combines subjects such as T cell, Stimulation, Active tb and Viral load with his study of Antigen. His biological study spans a wide range of topics, including Lineage and Mycobacterium.
Tom H. M. Ottenhoff mainly focuses on Tuberculosis, Mycobacterium tuberculosis, Immunology, Immune system and Disease. The various areas that Tom H. M. Ottenhoff examines in his Tuberculosis study include Transcriptome and Medical emergency. The Mycobacterium tuberculosis study combines topics in areas such as Innate immune system, Macrophage, Immunization and Creatine.
His research in the fields of Antigen, T cell, Antibody response and Cytokine overlaps with other disciplines such as Macaque. His research integrates issues of Receptor, Lymphocyte activation and Antigen presentation in his study of Antigen. His Immune system research includes elements of Ex vivo, Downregulation and upregulation, Interferon and Whole blood.
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Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria
Frank A. W. Verreck;Tjitske de Boer;Dennis M. L. Langenberg;Marieke A. Hoeve.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient Patients
Rolien de Jong;Frédéric Altare;Inez-Anne Haagen;Diënne G. Elferink.
Innate Immunity to Mycobacterium tuberculosis
Reinout van Crevel;Tom H. M. Ottenhoff;Jos W. M. van der Meer.
Clinical Microbiology Reviews (2002)
Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.
Mary E. Morgan;Jolanda H.M. van Bilsen;Aleida M. Bakker;Bianca Heemskerk.
Human Immunology (2005)
A blood RNA signature for tuberculosis disease risk: a prospective cohort study.
Daniel E Zak;Adam Penn-Nicholson;Thomas J Scriba;Ethan Thompson.
The Lancet (2016)
Vaccines against tuberculosis: where are we and where do we need to go?
Tom H. M. Ottenhoff;Stefan H. E. Kaufmann.
PLOS Pathogens (2012)
The Effect of Type 2 Diabetes Mellitus on the Presentation and Treatment Response of Pulmonary Tuberculosis
Bachti Alisjahbana;Edhyana Sahiratmadja;Erni J. Nelwan;Anugrah Maya Purwa.
Clinical Infectious Diseases (2007)
Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation.
Frank A. W. Verreck;Tjitske de Boer;Dennis M. L. Langenberg;Linda van der Zanden.
Journal of Leukocyte Biology (2006)
MANNOSE RECEPTOR-MEDIATED UPTAKE OF ANTIGENS STRONGLY ENHANCES HLA CLASS II-RESTRICTED ANTIGEN PRESENTATION BY CULTURED DENDRITIC CELLS
M. C. A. A. Tan;A. M. Mommaas;J. W. Drijfhout;R. Jordens.
European Journal of Immunology (1997)
Novel human immunodeficiencies reveal the essential role of type-1 cytokines in immunity to intracellular bacteria
Tom H.M Ottenhoff;Dinakantha Kumararatne;Jean-Laurent Casanova.
Immunology Today (1998)
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