H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 97 Citations 28,060 313 World Ranking 305 National Ranking 11
Medicine D-index 98 Citations 30,219 359 World Ranking 4074 National Ranking 117

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Internal medicine

Tom H. M. Ottenhoff spends much of his time researching Immunology, Tuberculosis, Mycobacterium tuberculosis, Virology and Immune system. His works in Cytokine, Immunity, Vaccination, Cellular immunity and T cell are all subjects of inquiry into Immunology. His Tuberculosis research is multidisciplinary, relying on both Acquired immune system, Interferon gamma, Internal medicine, Disease and Genetic variation.

Tom H. M. Ottenhoff has included themes like Tuberculin and Case-control study in his Mycobacterium tuberculosis study. His Virology research incorporates themes from Mycobacterium bovis, ESAT-6, Antigen and Microbiology. His research in Immune system intersects with topics in Inflammation and Cytotoxic T cell.

His most cited work include:

  • Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient Patients (738 citations)
  • Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria (714 citations)
  • Innate Immunity to Mycobacterium tuberculosis (499 citations)

What are the main themes of his work throughout his whole career to date?

Immunology, Tuberculosis, Mycobacterium tuberculosis, Antigen and Virology are his primary areas of study. His work in Immunology addresses subjects such as Disease, which are connected to disciplines such as Asymptomatic. His studies in Tuberculosis integrate themes in fields like Biomarker, Internal medicine and Vaccination.

His work carried out in the field of Mycobacterium tuberculosis brings together such families of science as Peripheral blood mononuclear cell and Interferon gamma. His Antigen research is multidisciplinary, incorporating elements of Cytotoxic T cell, Mycobacterium leprae and Antibody. His Virology research integrates issues from Mycobacterium bovis, Human leukocyte antigen, Microbiology and Immunogenicity.

He most often published in these fields:

  • Immunology (61.36%)
  • Tuberculosis (42.95%)
  • Mycobacterium tuberculosis (38.41%)

What were the highlights of his more recent work (between 2018-2021)?

  • Tuberculosis (42.95%)
  • Mycobacterium tuberculosis (38.41%)
  • Immunology (61.36%)

In recent papers he was focusing on the following fields of study:

Tom H. M. Ottenhoff mostly deals with Tuberculosis, Mycobacterium tuberculosis, Immunology, Antigen and Immune system. His Tuberculosis study integrates concerns from other disciplines, such as Biomarker, Internal medicine, Metabolomics and Transcriptome. His Mycobacterium tuberculosis study combines topics in areas such as Acquired immune system, Pathogen, Microbiology, CD8 and Effector.

His work deals with themes such as Downregulation and upregulation and Disease, which intersect with Immunology. He combines subjects such as T cell, Stimulation, Active tb and Viral load with his study of Antigen. His biological study spans a wide range of topics, including Lineage and Mycobacterium.

Between 2018 and 2021, his most popular works were:

  • Prevention of tuberculosis infection and disease by local BCG in repeatedly exposed rhesus macaques. (93 citations)
  • Harnessing donor unrestricted T-cells for new vaccines against tuberculosis. (23 citations)
  • Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome. (21 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Internal medicine

Tom H. M. Ottenhoff mainly focuses on Tuberculosis, Mycobacterium tuberculosis, Immunology, Immune system and Disease. The various areas that Tom H. M. Ottenhoff examines in his Tuberculosis study include Transcriptome and Medical emergency. The Mycobacterium tuberculosis study combines topics in areas such as Innate immune system, Macrophage, Immunization and Creatine.

His research in the fields of Antigen, T cell, Antibody response and Cytokine overlaps with other disciplines such as Macaque. His research integrates issues of Receptor, Lymphocyte activation and Antigen presentation in his study of Antigen. His Immune system research includes elements of Ex vivo, Downregulation and upregulation, Interferon and Whole blood.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

Frank A. W. Verreck;Tjitske de Boer;Dennis M. L. Langenberg;Marieke A. Hoeve.
Proceedings of the National Academy of Sciences of the United States of America (2004)

943 Citations

Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient Patients

Rolien de Jong;Frédéric Altare;Inez-Anne Haagen;Diënne G. Elferink.
Science (1998)

914 Citations

Innate Immunity to Mycobacterium tuberculosis

Reinout van Crevel;Tom H. M. Ottenhoff;Jos W. M. van der Meer.
Clinical Microbiology Reviews (2002)

746 Citations

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

Mary E. Morgan;Jolanda H.M. van Bilsen;Aleida M. Bakker;Bianca Heemskerk.
Human Immunology (2005)

592 Citations

Vaccines against tuberculosis: where are we and where do we need to go?

Tom H. M. Ottenhoff;Stefan H. E. Kaufmann.
PLOS Pathogens (2012)

502 Citations

Novel human immunodeficiencies reveal the essential role of type-1 cytokines in immunity to intracellular bacteria

Tom H.M Ottenhoff;Dinakantha Kumararatne;Jean-Laurent Casanova.
Immunology Today (1998)

447 Citations

The Effect of Type 2 Diabetes Mellitus on the Presentation and Treatment Response of Pulmonary Tuberculosis

Bachti Alisjahbana;Edhyana Sahiratmadja;Erni J. Nelwan;Anugrah Maya Purwa.
Clinical Infectious Diseases (2007)

439 Citations

Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation.

Frank A. W. Verreck;Tjitske de Boer;Dennis M. L. Langenberg;Linda van der Zanden.
Journal of Leukocyte Biology (2006)

436 Citations

MANNOSE RECEPTOR-MEDIATED UPTAKE OF ANTIGENS STRONGLY ENHANCES HLA CLASS II-RESTRICTED ANTIGEN PRESENTATION BY CULTURED DENDRITIC CELLS

M. C. A. A. Tan;A. M. Mommaas;J. W. Drijfhout;R. Jordens.
European Journal of Immunology (1997)

427 Citations

A blood RNA signature for tuberculosis disease risk: a prospective cohort study.

Daniel E Zak;Adam Penn-Nicholson;Thomas J Scriba;Ethan Thompson.
The Lancet (2016)

423 Citations

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