World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
114
Citations
43590
World Ranking
418
National Ranking
16

Medicine

D-Index
114
Citations
43619
World Ranking
4779
National Ranking
183

Tom H. M. Ottenhoff publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Tom H. M. Ottenhoff sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 522 publications — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Tom H. M. Ottenhoff D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Tom H. M. Ottenhoff sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 114 D-Index — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Tom H. M. Ottenhoff is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on Medicine and Immunology and Microbiology, reflecting an extensive body of work in these areas. The scientist has contributed significantly to studies within the subfields of Infectious Diseases, Immunology, Epidemiology, Molecular Biology, and Surgery.

The main research topics explored include Tuberculosis Research and Epidemiology, Mycobacterium research and diagnosis, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Viral Infections and Outbreaks Research, Immunodeficiency and Autoimmune Disorders, and Immune responses and vaccinations.

Frequent co-authors collaborating with Tom H. M. Ottenhoff are:

  • Simone A. Joosten
  • Mariëlle C. Haks
  • Kees L. M. C. Franken
  • Krista E. van Meijgaarden
  • Suzanne van Veen

The scientist has published extensively in several venues, with the most frequent being:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • iScience
  • Frontiers in Cellular and Infection Microbiology

Notable recent papers authored or co-authored by Tom H. M. Ottenhoff include:

  • RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response, 2020, Scientific Reports
  • Host-directed therapy to combat mycobacterial infections, 2021, Immunological Reviews
  • Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19, 2021, Nature Immunology
  • B-Cells and Antibodies as Contributors to Effector Immune Responses in Tuberculosis, 2021, Frontiers in Immunology
  • T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection, 2023, Nature Medicine

Best Publications

  • Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

    Frank A. W. Verreck;Tjitske de Boer;Dennis M. L. Langenberg;Marieke A. Hoeve

  • Innate immunity to Mycobacterium tuberculosis.

    Reinout van Crevel;Tom H M Ottenhoff;Jos W M van der Meer

  • Severe Mycobacterial and Salmonella Infections in Interleukin-12 Receptor-Deficient Patients

    Rolien de Jong;Frédéric Altare;Inez-Anne Haagen;Diënne G. Elferink

  • A blood RNA signature for tuberculosis disease risk: a prospective cohort study.

    Daniel E Zak;Adam Penn-Nicholson;Thomas J Scriba;Ethan Thompson

  • Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

    Mary E. Morgan;Jolanda H.M. van Bilsen;Aleida M. Bakker;Bianca Heemskerk

  • Vaccines against tuberculosis: where are we and where do we need to go?

    Tom H. M. Ottenhoff;Stefan H. E. Kaufmann

  • The Effect of Type 2 Diabetes Mellitus on the Presentation and Treatment Response of Pulmonary Tuberculosis

    Bachti Alisjahbana;Edhyana Sahiratmadja;Erni J. Nelwan;Anugrah Maya Purwa

  • Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation.

    Frank A. W. Verreck;Tjitske de Boer;Dennis M. L. Langenberg;Linda van der Zanden

  • MANNOSE RECEPTOR-MEDIATED UPTAKE OF ANTIGENS STRONGLY ENHANCES HLA CLASS II-RESTRICTED ANTIGEN PRESENTATION BY CULTURED DENDRITIC CELLS

    M. C. A. A. Tan;A. M. Mommaas;J. W. Drijfhout;R. Jordens

  • NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis.

    Gerben Ferwerda;Stephen E. Girardin;Bart Jan Kullberg;Lionel Le Bourhis

  • Novel human immunodeficiencies reveal the essential role of type-1 cytokines in immunity to intracellular bacteria

    Tom H.M Ottenhoff;Dinakantha Kumararatne;Jean-Laurent Casanova

  • Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study

    Myrsini Kaforou;Victoria J. Wright;Tolu Oni;Tolu Oni;Neil French;Neil French

  • Diagnosis of childhood tuberculosis and host RNA expression in Africa.

    Suzanne T. Anderson;Myrsini Kaforou;Andrew J. Brent;Victoria J. Wright

  • Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection

    Nadia Caccamo;Giuliana Guggino;Simone A. Joosten;Giuseppe Gelsomino

  • Selection of a human T helper type 1-like T cell subset by mycobacteria.

    J. B. A. G. Haanen;R. De Waal Malefijt;P. C. M. Res;E. M. Kraakman

  • Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1

    Coenraad Kuijl;Nigel D. L. Savage;Marije Marsman;Adriaan W. Tuin

  • Is there a future for TNF promoter polymorphisms

    J-P Bayley;T H M Ottenhoff;C L Verweij

  • Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis.

    Eliane M.S. Leyten;May Young Lin;Kees L.M.C. Franken;Annemieke H. Friggen

  • Purification of his-tagged proteins by immobilized chelate affinity chromatography: the benefits from the use of organic solvent.

    Kees L.M.C. Franken;Hoebert S. Hiemstra;Krista E. van Meijgaarden;Yanri Subronto

  • Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae.

    Tom H.M. Ottenhoff;Frank A.W. Verreck;Elgin G.R. Lichtenauer-Kaligis;Marieke A. Hoeve

Frequent Co-Authors

Kees L. M. C. Franken
Kees L. M. C. Franken Leiden University Medical Center
Krista E. van Meijgaarden
Krista E. van Meijgaarden Leiden University Medical Center
Annemieke Geluk
Annemieke Geluk Leiden University Medical Center
Simone A. Joosten
Simone A. Joosten Leiden University Medical Center
Hazel M. Dockrell
Hazel M. Dockrell London School of Hygiene & Tropical Medicine
Jaap T. van Dissel
Jaap T. van Dissel Leiden University Medical Center
Gerhard Walzl
Gerhard Walzl Stellenbosch University
Stefan H. E. Kaufmann
Stefan H. E. Kaufmann Max Planck Institute for Infection Biology
Reinout van Crevel
Reinout van Crevel Radboud University
Michèl R. Klein
Michèl R. Klein Leiden University Medical Center

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