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Chemistry

D-Index
52
Citations
9177
World Ranking
13562
National Ranking
1039

Overview

Yoshiki Yamaguchi is affiliated with Tohoku Medical and Pharmaceutical University in Japan. Their research primarily spans biochemistry, genetics, and molecular biology, with significant contributions in medicine. The main subfields of their work include molecular biology, organic chemistry, physiology, immunology, and neurology.

The scientist's research emphasis covers several key topics, including:

  • Glycosylation and Glycoproteins Research
  • Carbohydrate Chemistry and Synthesis
  • Monoclonal and Polyclonal Antibodies Research
  • Alzheimer's disease research and treatments
  • Enzyme Structure and Function
  • Galectins and Cancer Biology
  • Proteoglycans and glycosaminoglycans research

Yamaguchi has published extensively in various scientific venues. Frequent publication outlets include:

  • International Journal of Molecular Sciences
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Carbohydrate Research
  • Methods in molecular biology

Among their recent papers are:

  • High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies, 2020, Neuron
  • 3D Structure and Function of Glycosyltransferases Involved in N-glycan Maturation, 2020, International Journal of Molecular Sciences
  • Imaging α-synuclein pathologies in animal models and patients with Parkinson's and related diseases, 2024, Neuron
  • 3D Structures of IgA, IgM, and Components, 2021, International Journal of Molecular Sciences
  • Discovery of a new sialic acid binding region that regulates Siglec-7, 2020, Scientific Reports

Collaborations form an important part of Yamaguchi's scientific activity. Frequent co-authors include:

  • Noriyoshi Manabe
  • Shiho Ohno
  • Sushil K. Mishra
  • Shinobu Kitazume
  • Yasuhiko Kizuka

Best Publications

  • Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1.

    Shigeki Matsumiya;Yoshiki Yamaguchi;Jun-ichi Saito;Mayumi Nagano

  • Protein encapsulation within synthetic molecular hosts

    Daishi Fujita;Kosuke Suzuki;Sota Sato;Maho Yagi-Utsumi;Maho Yagi-Utsumi

  • Glycoform-dependent conformational alteration of the Fc region of human immunoglobulin G1 as revealed by NMR spectroscopy.

    Yoshiki Yamaguchi;Mamiko Nishimura;Mayumi Nagano;Hirokazu Yagi

  • Identification of a Post-translational Modification with Ribitol-Phosphate and Its Defect in Muscular Dystrophy

    Motoi Kanagawa;Kazuhiro Kobayashi;Michiko Tajiri;Hiroshi Manya

  • Modulation of E-cadherin function and dysfunction by N-glycosylation.

    Salomé S. Pinho;Raquel Seruca;Fátima Gärtner;Yoshiki Yamaguchi

  • An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease

    Yasuhiko Kizuka;Shinobu Kitazume;Reiko Fujinawa;Takashi Saito

  • GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi.

    Morihisa Fujita;Yusuke Maeda;Moonjin Ra;Yoshiki Yamaguchi

  • Synthesis of monoglucosylated high-mannose-type dodecasaccharide, a putative ligand for molecular chaperone, calnexin, and calreticulin

    Ichiro Matsuo;Megumi Wada;Shino Manabe;Yoshiki Yamaguchi

  • Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI

    Morihisa Fujita;Reika Watanabe;Nina Jaensch;Maria Romanova-Michaelides

  • Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity.

    Eri Sakata;Yoshiki Yamaguchi;Yasuhiro Miyauchi;Kazuhiro Iwai

  • Function and 3D Structure of the N-Glycans on Glycoproteins

    Masamichi Nagae;Yoshiki Yamaguchi

  • Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G.

    Shin Miyakawa;Yusuke Nomura;Taiichi Sakamoto;Yoshiki Yamaguchi

  • Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete the O-Glycosylated Form

    Shinobu Kitazume;Yuriko Tachida;Masaki Kato;Yoshiki Yamaguchi

  • A Platform of C-type Lectin-like Receptor CLEC-2 for Binding O-Glycosylated Podoplanin and Nonglycosylated Rhodocytin

    Masamichi Nagae;Kana Morita-Matsumoto;Masaki Kato;Mika Kato Kaneko

  • Up-and-down topological mode of amyloid β-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters

    Maho Utsumi;Yoshiki Yamaguchi;Hiroaki Sasakawa;Hiroaki Sasakawa;Naoki Yamamoto

  • Hydrogen Bonding Makes a Difference in the Rhodium-Catalyzed Enantioselective Hydrogenation Using Monodentate Phosphoramidites

    Yan Liu;Christian A. Sandoval;Yoshiki Yamaguchi;Xue Zhang

  • Pairing of oligosaccharides in the Fc region of immunoglobulin G

    Katsuyoshi Masuda;Yoshiki Yamaguchi;Koichi Kato;Noriko Takahashi

  • Structural Basis for Oligosaccharide Recognition of Misfolded Glycoproteins by OS-9 in ER-Associated Degradation

    Tadashi Satoh;Yang Chen;Dan Hu;Shinya Hanashima

  • Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugates

    Eri Sakata;Tadashi Satoh;Shunsuke Yamamoto;Yoshiki Yamaguchi

  • Structural basis of sugar-recognizing ubiquitin ligase.

    Tsunehiro Mizushima;Takeshi Hirao;Yukiko Yoshida;Soo Jae Lee

  • Sugar-binding Properties of VIP36, an Intracellular Animal Lectin Operating as a Cargo Receptor

    Yukiko Kamiya;Yoshiki Yamaguchi;Noriko Takahashi;Yoichiro Arata

  • Proteolytic fragmentation with high specificity of mouse immunoglobulin G mapping of proteolytic cleavage sites in the hinge region

    Yoshiki Yamaguchi;HaHyung Kim;Koichi Kato;Katsuyoshi Masuda

Frequent Co-Authors

Koichi Kato
Koichi Kato National Institutes of Natural Sciences
Naoyuki Taniguchi
Naoyuki Taniguchi Osaka University
Ichio Shimada
Ichio Shimada University of Tokyo
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Yuji Sugita
Yuji Sugita RIKEN Center for Biosystems Dynamics Research
Noriko Takahashi
Noriko Takahashi Nagoya City University
Yoshinao Wada
Yoshinao Wada Osaka Women's and Children's Hospital
Yoji Arata
Yoji Arata University of Tokyo
Yoshiyuki Adachi
Yoshiyuki Adachi Tokyo University of Pharmacy and Life Sciences
Tatsushi Toda
Tatsushi Toda University of Tokyo

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