The scientist’s investigation covers issues in Biochemistry, Tumor necrosis factor alpha, Cytokine, Glucan and Microbiology. The various areas that Yoshiyuki Adachi examines in his Biochemistry study include Molecular biology and Nitric oxide. His Tumor necrosis factor alpha study combines topics from a wide range of disciplines, such as Cathelicidin, Cathelicidins, Lipopolysaccharide and CD14.
His Cytokine study incorporates themes from In vitro and Signal transduction, Cell biology. His Glucan research is multidisciplinary, relying on both Alternative complement pathway, Mannan, Chromatography, Stereochemistry and Sodium hydroxide. Yoshiyuki Adachi interconnects Immunology, Immune system and CD40 in the investigation of issues within Microbiology.
Yoshiyuki Adachi focuses on Biochemistry, Glucan, Microbiology, Cytokine and Molecular biology. His Biochemistry study typically links adjacent topics like Nitric oxide. His study in Glucan is interdisciplinary in nature, drawing from both Grifola frondosa, Sparassis crispa, Ratón, Stereochemistry and Antibody.
He mostly deals with Candida albicans in his studies of Microbiology. He has included themes like Transfection, Gene expression, Immune system and Bone marrow in his Cytokine study. His Molecular biology study combines topics in areas such as Cell and Monoclonal antibody.
Yoshiyuki Adachi mainly investigates Biochemistry, Glucan, Microbiology, Innate immune system and Antibody. His research integrates issues of Mushroom, Mannan, Yeast, Receptor and Solubility in his study of Glucan. His research in Yeast focuses on subjects like Immune system, which are connected to Cryptococcus neoformans.
His Receptor study integrates concerns from other disciplines, such as Splenocyte and Interferon gamma. In Microbiology, Yoshiyuki Adachi works on issues like Vasculitis, which are connected to Flora and Immunology. As a part of the same scientific family, Yoshiyuki Adachi mostly works in the field of Cytotoxicity, focusing on Melanin and, on occasion, Cytokine.
His scientific interests lie mostly in Biochemistry, Glucan, Innate immune system, Yeast and Receptor. His study in Biochemistry is interdisciplinary in nature, drawing from both Molecular recognition and Antibody. Many of his studies on Glucan apply to Solubility as well.
His Innate immune system research is multidisciplinary, incorporating elements of CD11c, Intestinal mucosa, Interleukin 17 and Microbiology. Yoshiyuki Adachi combines subjects such as Sulfuric acid, Mannan, Immune system and Solubilization with his study of Yeast. In his work, Laminarin and C-type lectin is strongly intertwined with Escherichia coli, which is a subfield of Receptor.
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Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans.
Shinobu Saijo;Noriyuki Fujikado;Takahisa Furuta;Soo Hyun Chung.
Nature Immunology (2007)
Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans
Shinobu Saijo;Satoshi Ikeda;Keiko Yamabe;Shigeru Kakuta.
Immunity (2010)
Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 Higher Affinity than That with MD-2 or CD14
Sachiko Akashi;Shin-ichiroh Saitoh;Yasutaka Wakabayashi;Takane Kikuchi.
Journal of Experimental Medicine (2003)
Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells.
Isao Nagaoka;Satoko Hirota;François Niyonsaba;Michimasa Hirata.
Journal of Immunology (2001)
Characterization of β-Glucan Recognition Site on C-Type Lectin, Dectin 1
Yoshiyuki Adachi;Takashi Ishii;Yoshihiko Ikeda;Akiyoshi Hoshino.
Infection and Immunity (2004)
Antitumor β-Glucan from the Cultured Fruit Body of Agaricus blazei
Naohito Ohno;Mai Furukawa;Noriko N. Miura;Yoshiyuki Adachi.
Biological & Pharmaceutical Bulletin (2001)
Enhancement of Cytokine Production by Macrophages Stimulated with (1→3)-β-D-Glucan, Grifolan (GRN), Isolated from Grifola frondosa
Yoshiyuki Adachi;Mitsuhiro Okazaki;Naohito Ohno;Toshiro Yadomae.
Biological & Pharmaceutical Bulletin (1994)
Augmentation of the Lipopolysaccharide-Neutralizing Activities of Human Cathelicidin CAP18/LL-37-Derived Antimicrobial Peptides by Replacement with Hydrophobic and Cationic Amino Acid Residues
Isao Nagaoka;Satoko Hirota;François Niyonsaba;Michimasa Hirata.
Clinical and Vaccine Immunology (2002)
Structure-Activity Relationship of (1→3)-β-D-Glucans in the Induction of Cytokine Production from Macrophages, in Vitro
Mitsuhiro Okazaki;Yoshiyuki Adachi;Naohito Ohno;Toshiro Yadomae.
Biological & Pharmaceutical Bulletin (1995)
SOLUBILIZATION OF YEAST CELL-WALL BETA -(1 3)-D-GLUCAN BY SODIUM HYPOCHLORITE OXIDATION AND DIMETHYL SULFOXIDE EXTRACTION
Naohito Ohno;Michiharu Uchiyama;Aiko Tsuzuki;Kazuhiro Tokunaka.
Carbohydrate Research (1999)
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