D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 44 Citations 7,987 172 World Ranking 4004 National Ranking 160

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

The scientist’s investigation covers issues in Biochemistry, Tumor necrosis factor alpha, Cytokine, Glucan and Microbiology. The various areas that Yoshiyuki Adachi examines in his Biochemistry study include Molecular biology and Nitric oxide. His Tumor necrosis factor alpha study combines topics from a wide range of disciplines, such as Cathelicidin, Cathelicidins, Lipopolysaccharide and CD14.

His Cytokine study incorporates themes from In vitro and Signal transduction, Cell biology. His Glucan research is multidisciplinary, relying on both Alternative complement pathway, Mannan, Chromatography, Stereochemistry and Sodium hydroxide. Yoshiyuki Adachi interconnects Immunology, Immune system and CD40 in the investigation of issues within Microbiology.

His most cited work include:

  • Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans (526 citations)
  • Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. (504 citations)
  • Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 Higher Affinity than That with MD-2 or CD14 (333 citations)

What are the main themes of his work throughout his whole career to date?

Yoshiyuki Adachi focuses on Biochemistry, Glucan, Microbiology, Cytokine and Molecular biology. His Biochemistry study typically links adjacent topics like Nitric oxide. His study in Glucan is interdisciplinary in nature, drawing from both Grifola frondosa, Sparassis crispa, Ratón, Stereochemistry and Antibody.

He mostly deals with Candida albicans in his studies of Microbiology. He has included themes like Transfection, Gene expression, Immune system and Bone marrow in his Cytokine study. His Molecular biology study combines topics in areas such as Cell and Monoclonal antibody.

He most often published in these fields:

  • Biochemistry (35.86%)
  • Glucan (32.91%)
  • Microbiology (24.89%)

What were the highlights of his more recent work (between 2014-2021)?

  • Biochemistry (35.86%)
  • Glucan (32.91%)
  • Microbiology (24.89%)

In recent papers he was focusing on the following fields of study:

Yoshiyuki Adachi mainly investigates Biochemistry, Glucan, Microbiology, Innate immune system and Antibody. His research integrates issues of Mushroom, Mannan, Yeast, Receptor and Solubility in his study of Glucan. His research in Yeast focuses on subjects like Immune system, which are connected to Cryptococcus neoformans.

His Receptor study integrates concerns from other disciplines, such as Splenocyte and Interferon gamma. In Microbiology, Yoshiyuki Adachi works on issues like Vasculitis, which are connected to Flora and Immunology. As a part of the same scientific family, Yoshiyuki Adachi mostly works in the field of Cytotoxicity, focusing on Melanin and, on occasion, Cytokine.

Between 2014 and 2021, his most popular works were:

  • Production of low-molecular weight soluble yeast β-glucan by an acid degradation method. (18 citations)
  • β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner. (17 citations)
  • Modulation of an innate immune response by soluble yeast β-glucan prepared by a heat degradation method. (14 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Immune system

His scientific interests lie mostly in Biochemistry, Glucan, Innate immune system, Yeast and Receptor. His study in Biochemistry is interdisciplinary in nature, drawing from both Molecular recognition and Antibody. Many of his studies on Glucan apply to Solubility as well.

His Innate immune system research is multidisciplinary, incorporating elements of CD11c, Intestinal mucosa, Interleukin 17 and Microbiology. Yoshiyuki Adachi combines subjects such as Sulfuric acid, Mannan, Immune system and Solubilization with his study of Yeast. In his work, Laminarin and C-type lectin is strongly intertwined with Escherichia coli, which is a subfield of Receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans.

Shinobu Saijo;Noriyuki Fujikado;Takahisa Furuta;Soo Hyun Chung.
Nature Immunology (2007)

815 Citations

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

Shinobu Saijo;Satoshi Ikeda;Keiko Yamabe;Shigeru Kakuta.
Immunity (2010)

751 Citations

Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 Higher Affinity than That with MD-2 or CD14

Sachiko Akashi;Shin-ichiroh Saitoh;Yasutaka Wakabayashi;Takane Kikuchi.
Journal of Experimental Medicine (2003)

472 Citations

Cathelicidin family of antibacterial peptides CAP18 and CAP11 inhibit the expression of TNF-alpha by blocking the binding of LPS to CD14(+) cells.

Isao Nagaoka;Satoko Hirota;François Niyonsaba;Michimasa Hirata.
Journal of Immunology (2001)

343 Citations

Characterization of β-Glucan Recognition Site on C-Type Lectin, Dectin 1

Yoshiyuki Adachi;Takashi Ishii;Yoshihiko Ikeda;Akiyoshi Hoshino.
Infection and Immunity (2004)

282 Citations

Antitumor β-Glucan from the Cultured Fruit Body of Agaricus blazei

Naohito Ohno;Mai Furukawa;Noriko N. Miura;Yoshiyuki Adachi.
Biological & Pharmaceutical Bulletin (2001)

270 Citations

Enhancement of Cytokine Production by Macrophages Stimulated with (1→3)-β-D-Glucan, Grifolan (GRN), Isolated from Grifola frondosa

Yoshiyuki Adachi;Mitsuhiro Okazaki;Naohito Ohno;Toshiro Yadomae.
Biological & Pharmaceutical Bulletin (1994)

264 Citations

Augmentation of the Lipopolysaccharide-Neutralizing Activities of Human Cathelicidin CAP18/LL-37-Derived Antimicrobial Peptides by Replacement with Hydrophobic and Cationic Amino Acid Residues

Isao Nagaoka;Satoko Hirota;François Niyonsaba;Michimasa Hirata.
Clinical and Vaccine Immunology (2002)

213 Citations

Structure-Activity Relationship of (1→3)-β-D-Glucans in the Induction of Cytokine Production from Macrophages, in Vitro

Mitsuhiro Okazaki;Yoshiyuki Adachi;Naohito Ohno;Toshiro Yadomae.
Biological & Pharmaceutical Bulletin (1995)

196 Citations

SOLUBILIZATION OF YEAST CELL-WALL BETA -(1 3)-D-GLUCAN BY SODIUM HYPOCHLORITE OXIDATION AND DIMETHYL SULFOXIDE EXTRACTION

Naohito Ohno;Michiharu Uchiyama;Aiko Tsuzuki;Kazuhiro Tokunaka.
Carbohydrate Research (1999)

179 Citations

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