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Neuroscience

D-Index
52
Citations
9264
World Ranking
5348
National Ranking
2384

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jerrel L. Yakel is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on neuroscience, biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology and cellular and molecular neuroscience subfields.

Their recent publications cover a range of topics related to neuroinflammation, cholinergic regulation, and receptor mechanisms. Notable papers include:

  • A novel role of NLRP3-generated IL-1β in the acute-chronic transition of peripheral lipopolysaccharide-elicited neuroinflammation: implications for sepsis-associated neurodegeneration, 2020, Journal of Neuroinflammation
  • α7 nicotinic acetylcholine receptors in the hippocampal circuit: taming complexity, 2021, Trends in Neurosciences
  • Hippocampal Interneuronal α7 nAChRs Modulate Theta Oscillations in Freely Moving Mice, 2020, Cell Reports
  • Cholinergic Regulation of Hippocampal Theta Rhythm, 2022, Biomedicines
  • Loss of α7 nicotinic acetylcholine receptors in GABAergic neurons causes sex-dependent decreases in radial glia-like cell quantity and impairments in cognitive and social behavior, 2021, Brain Structure and Function

The main topics of Yakel's work include neuroscience and neuropharmacology research, studies of nicotinic acetylcholine receptors, receptor mechanisms and signaling, memory and neural mechanisms, photoreceptor and optogenetics research, vagus nerve stimulation research, and neuroinflammation and neurodegeneration mechanisms.

  • Neuroscience and Neuropharmacology Research
  • Nicotinic Acetylcholine Receptors Study
  • Receptor Mechanisms and Signaling
  • Memory and Neural Mechanisms
  • Photoreceptor and Optogenetics Research
  • Vagus Nerve Stimulation Research
  • Neuroinflammation and Neurodegeneration Mechanisms

Jerrel L. Yakel frequently collaborates with several researchers, including:

  • Jesse D. Cushman
  • Ayland C. Letsinger
  • Zhenglin Gu
  • Korey D. Stevanovic
  • Patricia W. Lamb

Their published work appears predominantly in journals such as bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, eNeuro, Journal of Neuroinflammation, and Trends in Neurosciences.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • eNeuro
  • Journal of Neuroinflammation
  • Trends in Neurosciences

Jerrel L. Yakel was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Nicotinic receptors in the brain: correlating physiology with function.

    Susan Jones;Sterling Sudweeks;Jerrel L. Yakel

  • Nicotinic ACh receptors as therapeutic targets in CNS disorders

    Kelly T. Dineley;Anshul A. Pandya;Jerrel L. Yakel

  • Cholinergic modulation of the hippocampal region and memory function.

    Juhee Haam;Jerrel L. Yakel

  • Desensitization of nicotinic ACh receptors: shaping cholinergic signaling

    Rashid Giniatullin;Andrea Nistri;Jerrel L. Yakel

  • Timing-Dependent Septal Cholinergic Induction of Dynamic Hippocampal Synaptic Plasticity

    Zhenglin Gu;Jerrel L. Yakel

  • Functional nicotinic ACh receptors on interneurones in the rat hippocampus

    Susan Jones;Jerrel L. Yakel

  • Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription

    Jerrel L. Yakel

  • 5-HT3 receptors mediate rapid responses in cultured hippocampus and a clonal cell line.

    Jerrel L. Yakel;Meyer B. Jackson

  • Functional and molecular characterization of neuronal nicotinic ACh receptors in rat CA1 hippocampal neurons.

    Sterling N. Sudweeks;Jerrel L. Yakel

  • Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system

    Jian-xin Shen;Jerrel L Yakel

  • Rat nicotinic ACh receptor α7 and β2 subunits co‐assemble to form functional heteromeric nicotinic receptor channels

    Serguei S. Khiroug;Patricia C. Harkness;Patricia W. Lamb;Sterling N. Sudweeks

  • β-Amyloid1–42 Peptide Directly Modulates Nicotinic Receptors in the Rat Hippocampal Slice

    Unknown

  • Multiple subunits of a voltage-dependent potassium channel contribute to the binding site for tetraethylammonium

    M.P. Kavanaugh;R.S. Hurst;J. Yakel;M.D. Varnum

  • Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes.

    J L Yakel;A Lagrutta;J P Adelman;R A North

  • Functional α7 Nicotinic ACh Receptors on Astrocytes in Rat Hippocampal CA1 Slices

    Jian-xin Shen;Jerrel L. Yakel

  • Functional Mapping and Ca2+ Regulation of Nicotinic Acetylcholine Receptor Channels in Rat Hippocampal CA1 Neurons

    Leonard Khiroug;Rashid Giniatullin;Rebecca C. Klein;Dmitriy Fayuk

  • A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors

    Marijke Brams;Anshul Pandya;Dmitry Kuzmin;René van Elk

  • Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors.

    Jerrel L. Yakel;Prabhakar Vissavajjhala;Victor A. Derkach;Debra A. Brickey

  • Cholinergic receptors: functional role of nicotinic ACh receptors in brain circuits and disease.

    Jerrel L. Yakel

  • The selectivity of the channel coupled to the 5-HT3 receptor.

    Jerrel L. Yakel;Xuesi M. Shao;Meyer B. Jackson

  • Inhibition of neuronal nicotinic acetylcholine receptor channels expressed in Xenopus oocytes by β-amyloid1–42 peptide

    Patricia W. Lamb;Mark A. Melton;Jerrel L. Yakel

  • Cholinergic Coordination of Presynaptic and Postsynaptic Activity Induces Timing-Dependent Hippocampal Synaptic Plasticity

    Zhenglin Gu;Patricia W. Lamb;Jerrel L. Yakel

  • Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain

    Jie Wu;Jie Wu;Qiang Liu;Pei Tang;Jens D. Mikkelsen

Frequent Co-Authors

R. A. North
R. A. North University of Manchester
Boris Gutkin
Boris Gutkin École Normale Supérieure
Rashid Giniatullin
Rashid Giniatullin University of Eastern Finland
August B. Smit
August B. Smit Vrije Universiteit Amsterdam
Kelly T. Dineley
Kelly T. Dineley The University of Texas Medical Branch at Galveston
Andrea Nistri
Andrea Nistri International School for Advanced Studies

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