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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Neuroscience

D-Index
96
Citations
33832
World Ranking
861
National Ranking
26

Biology and Biochemistry

D-Index
96
Citations
33875
World Ranking
1824
National Ranking
35

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

August B. Smit is affiliated with Vrije Universiteit Amsterdam in the Netherlands. Their research spans key areas in biochemistry, genetics, molecular biology, and neuroscience.

The scientific work of August B. Smit predominantly covers the following fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Within these fields, primary subfields include:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Physiology
  • Neurology
  • Cognitive Neuroscience

The main research topics addressed in their work are:

  • Neuroscience and Neuropharmacology Research
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Memory and Neural Mechanisms
  • Cellular transport and secretion
  • Mitochondrial Function and Pathology
  • Neurogenesis and neuroplasticity mechanisms

August B. Smit has a significant number of publications in well-known journals and repositories, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • University of Groningen research database (University of Groningen / Centre for Information Technology)
  • Alzheimer s & Dementia
  • Cells
  • Biological Psychiatry

Recent papers authored or coauthored by them include:

  • "A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain" (2021) published in Nature Communications
  • "Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways" (2022) published in Nature Genetics
  • "Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions" (2020) published in Science Advances
  • "Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue" (2022) published in Nature Biotechnology
  • "NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95" (2021) published in Nature Communications

Collaboration has played an important role in their research output, with frequent co-authors including:

  • Frank Koopmans (44 co-publications)
  • Ka Wan Li (34 co-publications)
  • Ronald E. van Kesteren (33 co-publications)
  • Huibert D. Mansvelder (21 co-publications)
  • Christina F. de Veij Mestdagh (16 co-publications)

Best Publications

  • Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors.

    K Brejc;W J van Dijk;R V Klaassen;M Schuurmans

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Nicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in AChBP Crystal Structures

    Patrick H.N Celie;Sarah E van Rossum-Fikkert;Willem J van Dijk;Katjuša Brejc

  • SynGO : An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

    Frank Koopmans;Pim van Nierop;Maria Andres-Alonso;Andrea Byrnes

  • Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

    Jansen Pr;Watanabe K;Stringer S;Skene N

  • A glia-derived acetylcholine-binding protein that modulates synaptic transmission

    August B. Smit;Naweed I. Syed;Dick Schaap;Jan van Minnen

  • Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

    P.F. Sullivan;E.J.C. de Geus;G. Willemsen;M.R. James

  • Differential Transport and Local Translation of Cytoskeletal, Injury-Response, and Neurodegeneration Protein mRNAs in Axons

    Dianna Willis;Ka Wan Li;Jun-Qi Zheng;Jay H Chang

  • Synapse formation between central neurons requires postsynaptic expression of the MEN1 tumor suppressor gene.

    Ronald E. van Kesteren;Naweed I. Syed;David W. Munno;Jildau Bouwman

  • Growth-controlling molluscan neurons produce the precursor of an insulin-related peptide.

    A. B. Smit;E. Vreugdenhil;R. H. M. Ebberink;W. P. M. Geraerts

  • Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.

    Patrick H N Celie;Igor E Kasheverov;Dmitry Y Mordvintsev;Ronald C Hogg

  • Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells

    Ishaan Gupta;Paul G Collier;Bettina Haase;Ahmed Mahfouz;Ahmed Mahfouz;Ahmed Mahfouz

  • CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation

    Silvia De Rubeis;Emanuela Pasciuto;Ka Wan Li;Esperanza Fernández

  • Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats

    Walter Adriani;Sabine Spijker;Véronique Deroche-Gamonet;Giovanni Laviola

  • CKAMP44: A Brain-Specific Protein Attenuating Short-Term Synaptic Plasticity in the Dentate Gyrus

    Jakob von Engelhardt;Volker Mack;Rolf Sprengel;Netta Kavenstock

  • Proteomics Analysis of Rat Brain Postsynaptic Density IMPLICATIONS OF THE DIVERSE PROTEIN FUNCTIONAL GROUPS FOR THE INTEGRATION OF SYNAPTIC PHYSIOLOGY

    Ka Wan Li;Martin P. Hornshaw;Roel C. Van der Schors;Rod Watson

  • Distributed network actions by nicotine increase the threshold for spike-timing-dependent plasticity in prefrontal cortex.

    Jonathan J. Couey;Rhiannon M. Meredith;Sabine Spijker;Rogier B. Poorthuis

  • Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

    Joanna A. Korecka;Ronald E. van Kesteren;Eva Blaas;Sonia O. Spitzer

  • Oligodendroglial myelination requires astrocyte-derived lipids.

    Nutabi Camargo;Andrea Goudriaan;Anne-Lieke F van Deijk;Willem M. Otte

  • Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways

    Unknown

  • Optogenetic dissection of medial prefrontal cortex circuitry.

    Danai Riga;Mariana R. Matos;Annet Glas;August B. Smit

  • Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.

    Chris Ulens;Ronald C. Hogg;Patrick H. Celie;Daniel Bertrand

Frequent Co-Authors

Ka Wan Li
Ka Wan Li Vrije Universiteit Amsterdam
Sabine Spijker
Sabine Spijker Vrije Universiteit Amsterdam
Matthijs Verhage
Matthijs Verhage Vrije Universiteit Amsterdam
Danielle Posthuma
Danielle Posthuma Vrije Universiteit Amsterdam
Huibert D. Mansvelder
Huibert D. Mansvelder Vrije Universiteit Amsterdam
Titia K. Sixma
Titia K. Sixma Antoni van Leeuwenhoek Hospital
Joost Verhaagen
Joost Verhaagen Netherlands Institute for Neuroscience
Anton N. M. Schoffelmeer
Anton N. M. Schoffelmeer VU University Medical Center
Taco J. De Vries
Taco J. De Vries VU University Medical Center
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill

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