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Biology and Biochemistry

D-Index
63
Citations
10125
World Ranking
10483
National Ranking
273

Overview

Ka Wan Li is affiliated with Vrije Universiteit Amsterdam in the Netherlands. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. Within these areas, their work addresses key subfields including Molecular Biology, Cellular and Molecular Neuroscience, Physiology, Spectroscopy, and Oncology.

The scientist's research topics encompass Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology research, Cellular transport and secretion, Cancer immunotherapy and biomarkers, Advanced proteomics techniques and applications, Neuroinflammation and neurodegeneration mechanisms, and Mass spectrometry techniques and applications.

Ka Wan Li has contributed to several peer-reviewed publications. Some notable recent papers include:

  • "Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions" (2020, Science Advances)
  • "Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits" (2020, Cell)
  • "Recent Developments in Data Independent Acquisition (DIA) Mass Spectrometry: Application of Quantitative Analysis of the Brain Proteome" (2020, Frontiers in Molecular Neuroscience)
  • "MS-DAP Platform for Downstream Data Analysis of Label-Free Proteomics Uncovers Optimal Workflows in Benchmark Data Sets and Increased Sensitivity in Analysis of Alzheimer's Biomarker Data" (2022, Journal of Proteome Research)
  • "The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer's disease" (2021, Acta Neuropathologica)

Their work is published across multiple venues, with frequent publications in bioRxiv (Cold Spring Harbor Laboratory), Annals of Oncology, Cells, Acta Neuropathologica Communications, and eLife.

Frequent coauthors collaborating with Ka Wan Li include August B. Smit, Frank Koopmans, Miguel A. Gonzalez-Lozano, Iryna Paliukhovich, and Suzanne S. M. Miedema.

In addition to journal articles, Ka Wan Li has contributed to book publications, including the title Synaptic Plasticity and Dysfunction, Friend or Foe? released in 2023 by Frontiers Media.

Best Publications

  • Differential Transport and Local Translation of Cytoskeletal, Injury-Response, and Neurodegeneration Protein mRNAs in Axons

    Dianna Willis;Ka Wan Li;Jun-Qi Zheng;Jay H Chang

  • CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation

    Silvia De Rubeis;Emanuela Pasciuto;Ka Wan Li;Esperanza Fernández

  • CKAMP44: A Brain-Specific Protein Attenuating Short-Term Synaptic Plasticity in the Dentate Gyrus

    Jakob von Engelhardt;Volker Mack;Rolf Sprengel;Netta Kavenstock

  • Proteomics Analysis of Rat Brain Postsynaptic Density IMPLICATIONS OF THE DIVERSE PROTEIN FUNCTIONAL GROUPS FOR THE INTEGRATION OF SYNAPTIC PHYSIOLOGY

    Ka Wan Li;Martin P. Hornshaw;Roel C. Van der Schors;Rod Watson

  • Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking.

    Michel C Van den Oever;Natalia A Goriounova;Ka Wan Li;Roel C Van der Schors

  • Neuropeptide expression and processing as revealed by direct matrix-assisted laser desorption ionization mass spectrometry of single neurons

    C. R. Jimenez;P. A. van Veelen;K. W. Li;W. C. Wildering

  • Profiling the human hippocampal proteome at all pathologic stages of Alzheimer's disease

    David C. Hondius;David C. Hondius;Pim van Nierop;Ka Wan Li;Jeroen J.M. Hoozemans

  • Hitchhiking of Cu/Zn superoxide dismutase to peroxisomes--evidence for a natural piggyback import mechanism in mammals.

    Markus Islinger;Ka Wan Li;Jürgen Seitz;Alfred Völkl

  • The CLAVATA3/ESR motif of CLAVATA3 is functionally independent from the nonconserved flanking sequences

    Martijn Fiers;Elzbieta Golemiec;Roel van der Schors;Lonneke van der Geest

  • Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer’s disease

    Marlene J Végh;Céline M Heldring;Willem Kamphuis;Sara Hijazi

  • Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence

    Danielle S Counotte;Natalia A Goriounova;Ka Wan Li;Maarten Loos

  • Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking.

    Michel Christian Van den Oever;Bart Lubbers;Natalia A Goriounova;Ka Wan Li

  • Rat liver peroxisomes after fibrate treatment: A survey using quantitative mass spectrometry

    Markus Islinger;Georg H. Lüers;Ka Wan Li;Maarten Loos

  • Towards Understanding the Role of Insulin in the Brain: Lessons from Insulin-related Signaling Systems in the Invertebrate Brain

    A.B Smit;R.E Van Kesteren;K.W Li;J Van Minnen

  • Direct mass spectrometric peptide profiling and sequencing of single neurons reveals differential peptide patterns in a small neuronal network

    C. R. Jimenez;K. W. Li;K. Dreisewerd;S. Spijker

  • Proteomics, ultrastructure, and physiology of hippocampal synapses in a fragile X syndrome mouse model reveal presynaptic phenotype

    Patricia Klemmer;Rhiannon M. Meredith;Carl D. Holmgren;Oleg I. Klychnikov

  • Direct peptide profiling of single neurons by matrix‐assisted laser desorption–ionization mass spectrometry

    P. A. van Veelen;C. R. Jiménez;K. W. Li;W. C. Wildering

  • Cloning, Characterization, and Expression of a G-Protein-Coupled Receptor from Lymnaea stagnalis and Identification of a Leucokinin-Like Peptide, PSFHSWSamide, as Its Endogenous Ligand

    Kingsley J. A. Cox;Cornelis P. Tensen;Roel C. Van der Schors;Ka Wan Li

  • Functional implications of neurotransmitter expression during axonal regeneration: Serotonin, but not peptides, auto-regulate axon growth of an identified central neuron

    Cornelis E. Koert;Gaynor E. Spencer;Jan van Minnen;Ka Wan Li

  • Isolation and structural characterization of an insulin‐related molecule, a predominant neuropeptide from Locusta migratoria

    Charles Hetru;Ka Wan Li;Philippe Bulet;Marie Lagueux

Frequent Co-Authors

August B. Smit
August B. Smit Vrije Universiteit Amsterdam
Connie R. Jimenez
Connie R. Jimenez Vrije Universiteit Amsterdam
Sabine Spijker
Sabine Spijker Vrije Universiteit Amsterdam
Matthijs Verhage
Matthijs Verhage Vrije Universiteit Amsterdam
Huibert D. Mansvelder
Huibert D. Mansvelder Vrije Universiteit Amsterdam
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Claudia Bagni
Claudia Bagni University of Rome Tor Vergata
Danielle Posthuma
Danielle Posthuma Vrije Universiteit Amsterdam
J. van der Greef
J. van der Greef Leiden University
Alma L. Burlingame
Alma L. Burlingame University of California, San Francisco

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