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Neuroscience

D-Index
41
Citations
8305
World Ranking
7791
National Ranking
3348

Overview

Scott E. Hemby is affiliated with High Point University in the United States and specializes in neuroscience with a particular focus on pharmacology, organic chemistry, and cellular and molecular neuroscience. Their research integrates aspects of biochemistry and molecular biology, addressing complex biochemical processes and molecular signaling pathways.

Their scientific contributions cover significant topics including chemical synthesis and alkaloids, neurotransmitter receptor influence on behavior, and the pharmacological mechanisms of alkaloids. Additionally, their work involves traditional and medicinal uses of Annonaceae plants, receptor mechanisms and signaling, as well as plant pathogens and fungal diseases.

Frequent co-authors collaborating with Scott E. Hemby include Scot McIntosh, Nicholas H. Oberlies, Leia S. Stallings, Panos Roussos, and Chang-Gyu Hahn, each contributing to various multidisciplinary projects within their research scope.

Scott E. Hemby's publication record includes peer-reviewed articles in a range of scientific journals with a concentration of work in venues such as UNC Libraries, Molecular Psychiatry, Scientific Reports, Journal of Medicinal Chemistry, and Nature Communications.

  • Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions, 2020, Scientific Reports
  • Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder, 2023, Journal of Medicinal Chemistry
  • Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models, 2024, Nature Communications
  • Three diketomorpholines from a Penicillium sp. (strain G1071), 2021, Phytochemistry
  • Chronic haloperidol administration downregulates select BDNF transcript and protein levels in the dorsolateral prefrontal cortex of rhesus monkeys, 2023, Frontiers in Psychiatry

These publications illustrate their involvement in areas such as drug interaction studies, therapeutic developments for substance use disorders, neuropharmacology, and natural product chemistry.

Best Publications

  • Molecular and Functional Profiling of Memory CD8 T Cell Differentiation

    Susan M. Kaech;Scott Hemby;Ellen Kersh;Rafi Ahmed

  • Gene expression elucidates functional impact of polygenic risk for schizophrenia

    Menachem Fromer;Panos Roussos;Solveig K. Sieberts;Jessica S. Johnson

  • Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons.

    Stephen D. Ginsberg;Scott E. Hemby;Virginia M.‐Y. Lee;James H. Eberwine

  • Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat

    S. E. Hemby;Conchita Co;Timothy R. Koves;James E. Smith

  • Gene Expression Profile for Schizophrenia: Discrete Neuron Transcription Patterns in the Entorhinal Cortex

    Scott E. Hemby;Stephen D. Ginsberg;Brian Brunk;Steven E. Arnold

  • CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.

    Gabriel E. Hoffman;Jaroslav Bendl;Georgios Voloudakis;Kelsey S. Montgomery

  • Two-dimensional fluorescence difference gel electrophoresis for comparative proteomics profiling.

    Nilesh S Tannu;Scott E Hemby

  • Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques

    Stephen D. Ginsberg;Peter B. Crino;Scott E. Hemby;Jeremy A. Weingarten

  • PRESENCE AND PHOSPHORYLATION OF TRANSCRIPTION FACTORS IN DEVELOPING DENDRITES

    Peter Crino;Kamran Khodakhah;Kevin Becker;Stephen Ginsberg

  • Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus.

    J Martin Verkuyl;Scott E Hemby;Marian Joëls

  • Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine

    Scott E. Hemby;Scot McIntosh;Francisco Leon;Stephen J. Cutler

  • Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.

    Amanda Dobbyn;Laura M Huckins;James Boocock;Laura G Sloofman

  • Proteomics for protein expression profiling in neuroscience.

    Willard M. Freeman;Scott E. Hemby

  • The effects of intravenous heroin administration on extracellular nucleus accumbens dopamine concentrations as determined by in vivo microdialysis.

    S E Hemby;T J Martin;C Co;S I Dworkin

  • Aerobic Exercise Attenuates Reinstatement of Cocaine-Seeking Behavior and Associated Neuroadaptations in the Prefrontal Cortex

    Wendy J. Lynch;Kristen B. Piehl;Glen Acosta;Alexis B. Peterson

  • Molecular profiling of midbrain dopamine regions in cocaine overdose victims.

    Wen Xue Tang;Wendy H. Fasulo;Deborah C. Mash;Scott E. Hemby

  • Synergistic Elevations in Nucleus Accumbens Extracellular Dopamine Concentrations during Self-Administration of Cocaine/Heroin Combinations (Speedball) in Rats

    Scott E. Hemby;Conchita Co;Steven I. Dworkin;James E. Smith

  • Neuron-specific age-related decreases in dopamine receptor subtype mRNAs.

    Scott E. Hemby;John Q. Trojanowski;Stephen D. Ginsberg

  • Incubation of nicotine seeking is associated with enhanced protein kinase A-regulated signaling of dopamine- and cAMP-regulated phosphoprotein of 32 kDa in the insular cortex

    Amir Abdolahi;Glen Acosta;Florence J. Breslin;Scott E. Hemby

  • Single-Cell Gene Expression Analysis: Implications for Neurodegenerative and Neuropsychiatric Disorders

    Stephen D. Ginsberg;Irina Elarova;Marc Ruben;Fengzhu Tan

  • Conditioned locomotor activity but not conditioned place preference following intra-accumbens infusions of cocaine.

    SE Hemby;GH Jones;Jr Jb Justice;DB Neill

Frequent Co-Authors

Stephen D. Ginsberg
Stephen D. Ginsberg Nathan Kline Institute for Psychiatric Research
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
David Friedman
David Friedman Columbia University
Raquel E. Gur
Raquel E. Gur University of Pennsylvania
David A. Lewis
David A. Lewis University of Pittsburgh
Vahram Haroutunian
Vahram Haroutunian Icahn School of Medicine at Mount Sinai
G.H. Jones
G.H. Jones Emory University
Leonard L. Howell
Leonard L. Howell Emory University
Bernie Devlin
Bernie Devlin University of Pittsburgh
Joseph D. Buxbaum
Joseph D. Buxbaum Icahn School of Medicine at Mount Sinai

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