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Genetics

D-Index
64
Citations
14394
World Ranking
2798
National Ranking
51

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Claudia Bagni is affiliated with the University of Rome Tor Vergata in Italy. Their research spans critical topics in biochemistry, genetics, molecular biology, and neuroscience, reflecting a multidisciplinary approach to understanding complex biological processes.

Bagni's work encompasses several focused fields of study including molecular biology, genetics, cognitive neuroscience, cellular and molecular neuroscience, and cell biology.

The main research topics explored by Bagni include:

  • Genetics and neurodevelopmental disorders
  • Autism spectrum disorder research
  • Ubiquitin and proteasome pathways
  • RNA modifications and cancer
  • Congenital heart defects research
  • Epigenetics and DNA methylation
  • Single-cell and spatial transcriptomics

Key publication venues where Bagni has contributed multiple works are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuron
  • Nature
  • Nature Communications
  • Neuroscience

Frequent co-authors collaborating with Bagni include:

  • G Pedini
  • Tilmann Achsel
  • Alexandros K. Kanellopoulos
  • Vittoria Mariano
  • Eleonora Rosina

Recent significant papers authored or co-authored by Bagni are:

  • "LifeTime and improving European healthcare through cell-based interceptive medicine" (2020), published in Nature
  • "Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits" (2020), published in Cell
  • "Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice" (2022), published in Nature Communications
  • "Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity" (2022), published in Science
  • "Stress undermines reward-guided cognitive performance through synaptic depression in the lateral habenula" (2021), published in Neuron

Recognition of Bagni's contributions to molecular biology and neuroscience includes membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • SynGO : An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

    Frank Koopmans;Pim van Nierop;Maria Andres-Alonso;Andrea Byrnes

  • The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses.

    Francesca Zalfa;Marcello Giorgi;Beatrice Primerano;Annamaria Moro

  • The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.

    Ilaria Napoli;Ilaria Napoli;Valentina Mercaldo;Pietro Pilo Boyl;Boris Eleuteri

  • From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome

    Claudia Bagni;William T. Greenough

  • Chemical stimulation of synaptosomes modulates alpha -Ca2+/calmodulin-dependent protein kinase II mRNA association to polysomes.

    Claudia Bagni;Liliana Mannucci;Carlos G. Dotti;Francesco Amaldi

  • A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

    Annette Schenck;Barbara Bardoni;Annamaria Moro;Claudia Bagni

  • Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

    Kim De Keersmaecker;Zeynep Kalender Atak;Ning Li;Carmen Vicente

  • A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability

    Francesca Zalfa;Boris Eleuteri;Kirsten S Dickson;Valentina Mercaldo

  • Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics

    Claudia Bagni;Flora Tassone;Giovanni Neri;Randi J Hagerman

  • Enriched environment promotes behavioral and morphological recovery in a mouse model for the fragile X syndrome.

    Leonardo Restivo;Francesca Ferrari;Enrica Passino;Carmelo Sgobio

  • CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formation

    Silvia De Rubeis;Emanuela Pasciuto;Ka Wan Li;Esperanza Fernández

  • Reduced FMR1 mRNA translation efficiency in fragile X patients with premutations.

    Beatrice Primerano;Flora Tassone;Randi J Hagerman;Paul J Hagerman

  • Elevated FMR1 mRNA in premutation carriers is due to increased transcription

    Flora Tassone;Alexandra Beilina;Chiara Carosi;Serena Albertosi

  • Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif.

    Francesca Zalfa;Salvatore Adinolfi;Ilaria Napoli;Eva Kühn-Hölsken

  • mRNPs, polysomes or granules: FMRP in neuronal protein synthesis.

    Francesca Zalfa;Tilmann Achsel;Claudia Bagni

  • Molecular dissection of the events leading to inactivation of the FMR1 gene

    Roberta Pietrobono;Elisabetta Tabolacci;Francesca Zalfa;Ilaria Zito

  • The fragile X mental retardation protein-RNP granules show an mGluR-dependent localization in the post-synaptic spines

    Francesca Ferrari;Valentina Mercaldo;Giovanni Piccoli;Carlo Sala

  • Fragile X mental retardation protein control of neuronal mRNA metabolism: Insights into mRNA stability

    Silvia De Rubeis;Claudia Bagni;Claudia Bagni

  • Cognitive Dysfunctions in Intellectual Disabilities: The Contributions of the Ras-MAPK and PI3K-AKT-mTOR Pathways

    Sarah C Borrie;Hilde Brems;Eric Legius;Claudia Bagni;Claudia Bagni;Claudia Bagni

  • Two-Stage Translational Control of Dentate Gyrus LTP Consolidation Is Mediated by Sustained BDNF-TrkB Signaling to MNK

    Debabrata Panja;Justin W. Kenney;Laura D’Andrea;Francesca Zalfa

Frequent Co-Authors

Carlos G. Dotti
Carlos G. Dotti Spanish National Research Council
Flora Tassone
Flora Tassone University of California, Davis
Seth G. N. Grant
Seth G. N. Grant University of Edinburgh
Rudi D'Hooge
Rudi D'Hooge KU Leuven
Giovanni Neri
Giovanni Neri Catholic University of the Sacred Heart
Vito Michele Fazio
Vito Michele Fazio Università Campus Bio-Medico
Randi J Hagerman
Randi J Hagerman University of California, Davis
Ben A. Oostra
Ben A. Oostra Erasmus University Rotterdam

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