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Detlef Balschun

Detlef Balschun

D-Index & Metrics

Neuroscience

D-Index
48
Citations
9515
World Ranking
6172
National Ranking
77

Overview

Detlef Balschun is affiliated with KU Leuven in Belgium and has contributed extensively to research in medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their work spans multiple subfields including physiology, cellular and molecular neuroscience, molecular biology, pharmacology, and nutrition and dietetics.

The research topics covered by Detlef Balschun focus primarily on Alzheimer's disease research and treatments, neuroscience and neuropharmacology research, and the study of cholinesterase related to neurodegenerative diseases. Additional areas of interest include trace elements in health, neuroinflammation and neurodegeneration mechanisms, dementia and cognitive impairment research, and cellular transport and secretion.

Balschun has published in several prominent scientific journals with frequent publications in:

  • Alzheimer's Research & Therapy
  • Frontiers in Molecular Neuroscience
  • Cerebral Cortex
  • Advances in Redox Research

Their recent papers include:

  • The two faces of synaptic failure in AppNL-G-F knock-in mice, 2020, Alzheimer's Research & Therapy
  • Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy, 2020, Frontiers in Molecular Neuroscience
  • Syndapin I Loss-of-Function in Mice Leads to Schizophrenia-Like Symptoms, 2020, Cerebral Cortex
  • A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice, 2023, Alzheimer's Research & Therapy
  • Identification and quantification of ionising radiation-induced oxysterol formation in membranes of lens fibre cells, 2022, Advances in Redox Research

Collaborations have been a part of their scientific work, with frequent co-authors including Victor Sabanov, Tariq Ahmed, An Schreurs, Amira Latif-Hernandez, and Katleen Craessaerts.

Best Publications

  • Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

    Michael J. Schmeisser;Elodie Ey;Stephanie Wegener;Juergen Bockmann

  • A neuromodulatory role of interleukin-1β in the hippocampus

    H Schneider;F Pitossi;Detlef Balschun;A Wagner

  • Interleukin-6: a cytokine to forget

    Detlef Balschun;W Wetzel;A del Rey;F Pitossi

  • Involvement of neurogranin in the modulation of calcium/calmodulin-dependent protein kinase II, synaptic plasticity, and spatial learning: a study with knockout mice.

    Jhang Ho Pak;Freesia L. Huang;Junfa Li;Detlef Balschun

  • Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

    Astrid Sydow;Anneke Van der Jeugd;Fang Zheng;Tariq Ahmed

  • Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon.

    Wilko D. Altrock;Susanne tom Dieck;Susanne tom Dieck;Maxim Sokolov;Alexander C. Meyer

  • Neurogranin/RC3 enhances long-term potentiation and learning by promoting calcium-mediated signaling.

    Kuo-Ping Huang;Freesia L Huang;Tino Jäger;Junfa Li

  • Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory?

    Detlef Balschun;David P. Wolfer;Peter Gass;Theo Mantamadiotis

  • Sustained long term potentiation and anxiety in mice lacking the Mas protooncogene.

    Thomas Walther;Detlef Balschun;Jörg-Peter Voigt;Heidrun Fink

  • Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.

    Heather C. Rice;Heather C. Rice;Daniel de Malmazet;Daniel de Malmazet;An Schreurs;Samuel Frere

  • Deficits in Memory Tasks of Mice with CREB Mutations Depend on Gene Dosage

    Peter Gass;David P. Wolfer;Detlef Balschun;Dorothea Rudolph

  • A cytokine network involving brain-borne IL-1β, IL-1ra, IL-18, IL-6, and TNFα operates during long-term potentiation and learning.

    Adriana del Rey;Detlef Balschun;Wolfram Wetzel;Anke Randolf

  • A post-tetanic time window for the reinforcement of long-term potentiation by appetitive and aversive stimuli

    Thomas Seidenbecher;Klaus G. Reymann;Detlef Balschun

  • Tau deletion promotes brain insulin resistance.

    Elodie Marciniak;Antoine Leboucher;Emilie Caron;Tariq Ahmed;Tariq Ahmed

  • Requirement of β-adrenergic receptor activation and protein synthesis for LTP-reinforcement by novelty in rat dentate gyrus

    Thomas Straube;Volker Korz;Detlef Balschun;Julietta Uta Frey

  • Deletion of the ryanodine receptor type 3 (RyR3) impairs forms of synaptic plasticity and spatial learning

    Detlef Balschun;David P. Wolfer;Federica Bertocchini;Virginia Barone

  • A Specific Role for Group I mGluRs in Hippocampal LTP and Hippocampus-Dependent Spatial Learning

    Detlef Balschun;Denise Manahan-Vaughan;Thomas Wagner;Thomas Behnisch

  • When Are Class I Metabotropic Glutamate Receptors Necessary for Long-Term Potentiation?

    Volker W. Wilsch;Thomas Behnisch;Tino Jäger;Klaus G. Reymann

  • Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau

    Ann Van der Jeugd;Katja Hochgräfe;Tariq Ahmed;Jochen Martin Decker

  • Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions

    Johannes Prox;Christian Bernreuther;Hermann Altmeppen;Jasper Grendel

  • Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion

    Tariq Ahmed;Anneke Van der Jeugd;David Blum;Marie-Christine Galas

Frequent Co-Authors

Rudi D'Hooge
Rudi D'Hooge KU Leuven
David Blum
David Blum University of Lille
Klaus G. Reymann
Klaus G. Reymann Leibniz Institute for Neurobiology
Claudia Bagni
Claudia Bagni University of Rome Tor Vergata
Eckart D. Gundelfinger
Eckart D. Gundelfinger Leibniz Institute for Neurobiology
Julietta Uta Frey
Julietta Uta Frey Leibniz Institute for Neurobiology
Werner Zuschratter
Werner Zuschratter Leibniz Institute for Neurobiology
Dirk Montag
Dirk Montag Leibniz Institute for Neurobiology
Robert Puers
Robert Puers KU Leuven

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