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102
Citations
39466
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7639
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Overview

Flora Tassone is affiliated with the University of California, Davis in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with an emphasis on neuroscience. The primary fields of study include biochemistry, genetics and molecular biology, and neuroscience, while subfields of specialization consist of genetics, molecular biology, cognitive neuroscience, cell biology, and clinical psychology.

The main research topics that Flora Tassone addresses center around genetics and neurodevelopmental disorders, autism spectrum disorder research, genomic variations and chromosomal abnormalities, epigenetics and DNA methylation, mitochondrial function and pathology, congenital heart defects research, and endoplasmic reticulum stress and disease.

Flora Tassone has published extensively in several scientific venues. Notably frequent publication outlets include Genes, Cells, Frontiers in Psychiatry, International Journal of Molecular Sciences, and the Journal of Neurodevelopmental Disorders.

Some of the recent papers authored or co-authored by Flora Tassone cover a range of topics, including insights into genetic architecture and clinical features of autism, and clinical trials related to fragile X syndrome. Key recent publications are:

  • Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on FMR1 Premutation (2023, Cells)
  • Rare coding variation provides insight into the genetic architecture and phenotypic context of autism (2022, Nature Genetics)
  • A randomized, controlled trial of ZYN002 cannabidiol transdermal gel in children and adolescents with fragile X syndrome (CONNECT-FX) (2022, Journal of Neurodevelopmental Disorders)
  • Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome (2020, Journal of Neurodevelopmental Disorders)
  • Episignatures Stratifying Helsmoortel-Van Der Aa Syndrome Show Modest Correlation with Phenotype (2020, The American Journal of Human Genetics)

Flora Tassone collaborates frequently with several researchers who have contributed extensively in related fields. These co-authors include Randi J. Hagerman, David Hessl, Andrea Schneider, Susan M. Rivera, and Marwa Zafarullah.

Best Publications

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

    F. Kyle Satterstrom;F. Kyle Satterstrom;Jack A. Kosmicki;Jiebiao Wang;Michael S. Breen

  • Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X.

    Randi J Hagerman;M. Leehey;W. Heinrichs;Flora Tassone

  • Elevated levels of FMR1 mRNA in carrier males : A new mechanism of involvement in the fragile-X syndrome

    Flora Tassone;Randi J. Hagerman;Randi J. Hagerman;Annette K. Taylor;Louise W. Gane

  • Fragile X Premutation Tremor/Ataxia Syndrome: Molecular, Clinical, and Neuroimaging Correlates

    Sébastien Jacquemont;Randi J. Hagerman;Maureen Leehey;Jim Grigsby

  • Fragile X syndrome

    Randi J. Hagerman;Elizabeth Berry-Kravis;Heather Cody Hazlett;Donald B. Bailey

  • Penetrance of the Fragile X–Associated Tremor/Ataxia Syndrome in a Premutation Carrier Population

    Sébastien Jacquemont;Randi J. Hagerman;Maureen A. Leehey;Deborah A. Hall

  • Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS)

    C. M. Greco;Robert F Berman;Ryan Martin;Flora Tassone

  • Neuronal intranuclear inclusions in a new cerebellar tremor/ataxia syndrome among fragile X carriers.

    C. M. Greco;Randi J Hagerman;Flora Tassone;A. E. Chudley

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

    F. Kyle Satterstrom;Jack A. Kosmicki;Jiebiao Wang;Michael S Breen;Michael S Breen

  • Mitochondrial Dysfunction in Autism

    Cecilia R Giulivi;Yi Fan Zhang;Alicja Omanska-Klusek;Catherine Ross-Inta

  • Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: a preliminary report.

    Lucy Jane Miller;D. N. McIntosh;J. McGrath;V. Shyu

  • Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study

    Rebecca Jean Schmidt;Daniel J Tancredi;Sally J Ozonoff;Robin L Hansen

  • Autism profiles of males with fragile X syndrome.

    Susan W. Harris;David R Hessl;Beth Goodlin-Jones;Jessica A Ferranti

  • Fragile X Premutation Carriers: Characteristic MR Imaging Findings of Adult Male Patients with Progressive Cerebellar and Cognitive Dysfunction

    James A. Brunberg;Sebastien Jacquemont;Randi J. Hagerman;Elizabeth M. Berry-Kravis

  • Fragile-X–Associated Tremor/Ataxia Syndrome (FXTAS) in Females with the FMR1 Premutation

    Randi J Hagerman;B. R. Leavitt;F. Farzin;S. Jacquemont

  • Protein composition of the intranuclear inclusions of FXTAS

    C. K. Iwahashi;D. H. Yasui;H. J. An;C. M. Greco

  • Autism spectrum disorders and attention-deficit/hyperactivity disorder in boys with the fragile X premutation.

    Faraz Farzin;Hazel Perry;David R Hessl;Danuta Loesch

  • Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics

    Claudia Bagni;Flora Tassone;Giovanni Neri;Randi J Hagerman

  • Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients

    Chantal Sellier;Frédérique Rau;Yilei Liu;Flora Tassone

  • FMRP expression as a potential prognostic indicator in fragile X syndrome.

    Flora Tassone;Randi J. Hagerman;Randi J. Hagerman;David N. Iklé;Pamela N. Dyer

Frequent Co-Authors

Randi J Hagerman
Randi J Hagerman University of California, Davis
Paul J. Hagerman
Paul J. Hagerman University of California, Davis
David R Hessl
David R Hessl University of California, Davis
Susan M. Rivera
Susan M. Rivera University of California, Davis
Elizabeth Berry-Kravis
Elizabeth Berry-Kravis Rush University Medical Center
Jim Grigsby
Jim Grigsby University of Colorado Denver
Tony J. Simon
Tony J. Simon University of California, Davis
Sébastien Jacquemont
Sébastien Jacquemont University of Montreal
Irva Hertz-Picciotto
Irva Hertz-Picciotto University of California, Davis
Isaac N. Pessah
Isaac N. Pessah University of California, Davis

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