Karen Usdin

Overview

Best Publications

• The biological effects of simple tandem repeats: Lessons from the repeat expansion diseases

  Karen Usdin

  352
  Citations

• CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro

  K. Usdin;K. J. Woodford

  345
  Citations

• The GAA•TTC triplet repeat expanded in Friedreich’s ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner

  Ed Grabczyk;Karen Usdin

  291
  Citations

• Repeat-induced epigenetic changes in intron 1 of the frataxin gene and its consequences in Friedreich ataxia

  Eriko Greene;Lata Mahishi;Ali Entezam;Daman Kumari

  269
  Citations

• Regional FMRP deficits and large repeat expansions into the full mutation range in a new Fragile X premutation mouse model

  Ali Entezam;Rea Biacsi;Bonnie Orrison;Tapas Saha

  212
  Citations

• Repeat instability during DNA repair: Insights from model systems.

  Karen Usdin;Nealia C M House;Catherine H Freudenreich

  186
  Citations

• The fragile X syndrome repeats form RNA hairpins that do not activate the interferon‐inducible protein kinase, PKR, but are cut by Dicer

  Vaishali Handa;Tapas Saha;Karen Usdin

  162
  Citations

• The Development and Use of a DNA Polymerase Arrest Assay for the Evaluation of Parameters Affecting Intrastrand Tetraplex Formation

  M. Neale Weitzmann;Kerry J. Woodford;Karen Usdin

  152
  Citations

• DNA repeat expansions and human disease

  K. Usdin;E. Grabczyk

  147
  Citations

• Repeat expansions confer WRN dependence in microsatellite-unstable cancers.

  Niek van Wietmarschen;Sriram Sridharan;William J. Nathan;Anthony Tubbs

  134
  Citations

• A novel K(+)-dependent DNA synthesis arrest site in a commonly occurring sequence motif in eukaryotes.

  K J Woodford;R M Howell;K Usdin

  133
  Citations

• Interaction of the Transcription Factors USF1, USF2, and α-Pal/Nrf-1 with the FMR1 Promoter IMPLICATIONS FOR FRAGILE X MENTAL RETARDATION SYNDROME

  Daman Kumari;Karen Usdin

  129
  Citations

• Linear plasmid vector for cloning of repetitive or unstable sequences in Escherichia coli

  Ronald Godiska;David Mead;Vinay Dhodda;Chengcang Wu

  123
  Citations

• NGG-triplet repeats form similar intrastrand structures: implications for the triplet expansion diseases

  K. Usdin

  123
  Citations

• Repeat Expansion Affects Both Transcription Initiation and Elongation in Friedreich Ataxia Cells

  Daman Kumari;Rea Erika Biacsi;Karen Usdin

  119
  Citations

• A mouse model of the fragile X premutation: effects on behavior, dendrite morphology, and regional rates of cerebral protein synthesis

  Mei Qin;Ali Entezam;Karen Usdin;Tianjian Huang

  119
  Citations

• SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome.

  Rea Biacsi;Daman Kumari;Karen Usdin

  117
  Citations

• The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in Fragile X syndrome

  Daman Kumari;Karen Usdin

  113
  Citations

• The mismatch repair protein MSH2 is rate limiting for repeat expansion in a fragile X premutation mouse model.

  Rachel Adihe Lokanga;Rachel Adihe Lokanga;Xiao-Nan Zhao;Karen Usdin

  108
  Citations

• DNA Secondary Structures and the Evolution of Hypervariable Tandem Arrays

  Kerry J. Woodford;Karen Usdin;M. Neale Weitzmann

  106
  Citations