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Genetics

D-Index
82
Citations
93581
World Ranking
1435
National Ranking
184

Overview

Jon W. Teague is affiliated with the Wellcome Sanger Institute in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these main fields, their work focuses significantly on Cancer Research, Molecular Biology, and Pulmonary and Respiratory Medicine.

Teague has contributed extensively to topics such as Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, and Lung Cancer Treatments and Mutations. Other areas of study include Lung Cancer Diagnosis and Treatment, Genomics and Phylogenetic Studies, Epigenetics and DNA Methylation, and the regulation of FOXO transcription factors.

Among recent papers authored or co-authored by Teague are:

  • COSMIC: a curated database of somatic variants and clinical data for cancer (2023), Nucleic Acids Research
  • Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor (2022), Cell Genomics
  • Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence (2021), Nature Genetics
  • Convergent somatic mutations in metabolism genes in chronic liver disease (2021), Nature
  • Geographic variation of mutagenic exposures in kidney cancer genomes (2024), Nature

The scientist frequently collaborates with several notable researchers, including Michael R. Stratton, Ludmil B. Alexandrov, Erik N. Bergstrom, Jingwei Wang, and Sarah Moody. These collaborations have generated a substantial number of joint publications.

Teague's work is published in a range of scientific journals, with multiple articles appearing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature, Cancer Research, Nature Genetics, and UNC Libraries.

Best Publications

  • Mutations of the BRAF gene in human cancer

    Helen Davies;Graham R. Bignell;Charles Cox;Philip Stephens

  • Signatures of mutational processes in human cancer

    Ludmil B. Alexandrov;Serena Nik-Zainal;Serena Nik-Zainal;David C. Wedge;Samuel A. J. R. Aparicio

  • Genomic Classification and Prognosis in Acute Myeloid Leukemia

    Elli Papaemmanuil;Moritz Gerstung;Lars Bullinger;Verena I Gaidzik

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer.

    Simon A. Forbes;Nidhi Bindal;Sally Bamford;Charlotte Cole

  • COSMIC: exploring the world's knowledge of somatic mutations in human cancer

    Simon A. Forbes;David Beare;Prasad Gunasekaran;Kenric Leung

  • Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

    Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Serena Nik-Zainal;Serena Nik-Zainal;Helen Davies;Johan Staaf;Manasa Ramakrishna

  • Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

    J. Nangalia;C.E. Massie;E.J. Baxter;F.L. Nice

  • Mutational Processes Molding the Genomes of 21 Breast Cancers

    Serena Nik-Zainal;Ludmil B. Alexandrov;David C. Wedge;Peter Van Loo;Peter Van Loo;Peter Van Loo

  • A comprehensive catalogue of somatic mutations from a human cancer genome

    Erin D. Pleasance;R. Keira Cheetham;Philip J. Stephens;David J. Mcbride

  • Clinical and biological implications of driver mutations in myelodysplastic syndromes.

    Elli Papaemmanuil;Moritz Gerstung;Luca Malcovati;Sudhir Tauro

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Exome sequencing identifies frequent mutation of the SWI/SNF Complex Gene PBRM1 in renal carcinoma

    Ignacio Varela;Patrick Tarpey;Keiran Raine;Dachuan Huang

  • The Life History of 21 Breast Cancers

    Serena Nik-Zainal;Peter Van Loo;Peter Van Loo;Peter Van Loo;David C. Wedge;Ludmil B. Alexandrov

  • The patterns and dynamics of genomic instability in metastatic pancreatic cancer

    Peter J. Campbell;Peter J. Campbell;Shinichi Yachida;Laura J. Mudie;Philip J. Stephens

  • Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

    E. Papaemmanuil;M. Cazzola;J. Boultwood;L. Malcovati

  • The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

    S Bamford;E Dawson;S Forbes;J Clements

Frequent Co-Authors

Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Keiran Raine
Keiran Raine Wellcome Sanger Institute
Adam Butler
Adam Butler Wellcome Sanger Institute
Andrew Menzies
Andrew Menzies Wellcome Sanger Institute
Peter Van Loo
Peter Van Loo The Francis Crick Institute
Patrick S. Tarpey
Patrick S. Tarpey Wellcome Sanger Institute
David C. Wedge
David C. Wedge University of Manchester
David T. Jones
David T. Jones University College London
Helen Davies
Helen Davies University of Cambridge

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