What is she best known for?
The fields of study she is best known for:
Her scientific interests lie mostly in Receptor, Biochemistry, Stereochemistry, Binding site and Ion channel.
In general Receptor, her work in Agonist, 5-HT3 receptor and Enzyme-linked receptor is often linked to Population linking many areas of study.
Her Biochemistry study frequently draws connections between related disciplines such as Biophysics.
Her Stereochemistry research is multidisciplinary, incorporating perspectives in Glycine receptor, Wild type, Cysteine, Ligand-gated ion channel and Nicotinic agonist.
Her research integrates issues of Homology modeling and Aromatic amino acids in her study of Binding site.
Her work carried out in the field of Ion channel brings together such families of science as Residue, Cytoplasm, Mutant and Allosteric regulation.
Her most cited work include:
- Cis – trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel (359 citations)
- Actions of imidacloprid and a related nitromethylene on cholinergic receptors of an identified insect motor neurone (260 citations)
- The structural basis of function in Cys-loop receptors (234 citations)
What are the main themes of her work throughout her whole career to date?
Sarah C.R. Lummis spends much of her time researching Receptor, Biochemistry, Binding site, Biophysics and Ion channel.
Her study brings together the fields of Stereochemistry and Receptor.
Her Binding site study combines topics in areas such as Antagonist, Docking and Mechanism of action.
As a part of the same scientific family, Sarah C.R. Lummis mostly works in the field of Biophysics, focusing on Protein structure and, on occasion, Peptide sequence.
Transmembrane protein is closely connected to Transmembrane domain in her research, which is encompassed under the umbrella topic of Ion channel.
Her research investigates the connection with Agonist and areas like Endocrinology which intersect with concerns in Nicotinic agonist and Acetylcholine receptor.
She most often published in these fields:
- Receptor (70.91%)
- Biochemistry (43.64%)
- Binding site (35.91%)
What were the highlights of her more recent work (between 2013-2021)?
- Ion channel (30.00%)
- Receptor (70.91%)
- Ligand-gated ion channel (21.82%)
In recent papers she was focusing on the following fields of study:
Ion channel, Receptor, Ligand-gated ion channel, Biophysics and Binding site are her primary areas of study.
Her work deals with themes such as Xenopus, Gating, Stereochemistry and Allosteric regulation, which intersect with Ion channel.
Her Receptor study integrates concerns from other disciplines, such as Amino acid and Cell biology.
Her Ligand-gated ion channel research incorporates themes from Voltage clamp, Membrane potential, Protein subunit, Protein structure and Cys-loop receptors.
Her Biophysics research is multidisciplinary, relying on both Biochemistry and Glycine receptor.
Sarah C.R. Lummis has researched Binding site in several fields, including Chimera, Acetylcholine binding, 5-HT3 receptor, Partial agonist and Gated Ion Channel.
Between 2013 and 2021, her most popular works were:
- The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors (77 citations)
- GABA(A) receptor modulation by terpenoids from Sideritis extracts. (44 citations)
- Structural Requirements in the Transmembrane Domain of GLIC Revealed by Incorporation of Noncanonical Histidine Analogs (18 citations)
In her most recent research, the most cited papers focused on:
Her primary areas of study are Receptor, Ion channel, Stereochemistry, Ligand-gated ion channel and Binding site.
Her Receptor study necessitates a more in-depth grasp of Biochemistry.
The study incorporates disciplines such as Mutagenesis, Patch clamp, Transmembrane domain and Transmembrane protein in addition to Ion channel.
The concepts of her Ligand-gated ion channel study are interwoven with issues in Memantine, Ligand, Voltage clamp, Cell membrane and Protein structure.
Her research in Binding site intersects with topics in Acetylcholine binding, Energy landscape, 5-HT3 receptor, Partial agonist and Gated Ion Channel.
Her biological study spans a wide range of topics, including Biophysics and Varenicline.
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