Her scientific interests lie mostly in Receptor, Biochemistry, Stereochemistry, Binding site and Ion channel. In general Receptor, her work in Agonist, 5-HT3 receptor and Enzyme-linked receptor is often linked to Population linking many areas of study. Her Biochemistry study frequently draws connections between related disciplines such as Biophysics.
Her Stereochemistry research is multidisciplinary, incorporating perspectives in Glycine receptor, Wild type, Cysteine, Ligand-gated ion channel and Nicotinic agonist. Her research integrates issues of Homology modeling and Aromatic amino acids in her study of Binding site. Her work carried out in the field of Ion channel brings together such families of science as Residue, Cytoplasm, Mutant and Allosteric regulation.
Sarah C.R. Lummis spends much of her time researching Receptor, Biochemistry, Binding site, Biophysics and Ion channel. Her study brings together the fields of Stereochemistry and Receptor. Her Binding site study combines topics in areas such as Antagonist, Docking and Mechanism of action.
As a part of the same scientific family, Sarah C.R. Lummis mostly works in the field of Biophysics, focusing on Protein structure and, on occasion, Peptide sequence. Transmembrane protein is closely connected to Transmembrane domain in her research, which is encompassed under the umbrella topic of Ion channel. Her research investigates the connection with Agonist and areas like Endocrinology which intersect with concerns in Nicotinic agonist and Acetylcholine receptor.
Ion channel, Receptor, Ligand-gated ion channel, Biophysics and Binding site are her primary areas of study. Her work deals with themes such as Xenopus, Gating, Stereochemistry and Allosteric regulation, which intersect with Ion channel. Her Receptor study integrates concerns from other disciplines, such as Amino acid and Cell biology.
Her Ligand-gated ion channel research incorporates themes from Voltage clamp, Membrane potential, Protein subunit, Protein structure and Cys-loop receptors. Her Biophysics research is multidisciplinary, relying on both Biochemistry and Glycine receptor. Sarah C.R. Lummis has researched Binding site in several fields, including Chimera, Acetylcholine binding, 5-HT3 receptor, Partial agonist and Gated Ion Channel.
Her primary areas of study are Receptor, Ion channel, Stereochemistry, Ligand-gated ion channel and Binding site. Her Receptor study necessitates a more in-depth grasp of Biochemistry. The study incorporates disciplines such as Mutagenesis, Patch clamp, Transmembrane domain and Transmembrane protein in addition to Ion channel.
The concepts of her Ligand-gated ion channel study are interwoven with issues in Memantine, Ligand, Voltage clamp, Cell membrane and Protein structure. Her research in Binding site intersects with topics in Acetylcholine binding, Energy landscape, 5-HT3 receptor, Partial agonist and Gated Ion Channel. Her biological study spans a wide range of topics, including Biophysics and Varenicline.
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Cis – trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel
Sarah C. R. Lummis;Darren L. Beene;Lori W. Lee;Henry A. Lester.
Actions of imidacloprid and a related nitromethylene on cholinergic receptors of an identified insect motor neurone
Donglin Bai;Sarah C. R. Lummis;Wolfgang Leicht;Heinz Breer.
Pesticide Science (1991)
The structural basis of function in Cys-loop receptors
Andrew J. Thompson;Henry A. Lester;Sarah C. R. Lummis.
Quarterly Reviews of Biophysics (2010)
The 5-HT3 receptor as a therapeutic target
Andrew J Thompson;Sarah C R Lummis.
Expert Opinion on Therapeutic Targets (2007)
The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review).
David C Reeves;Sarah C R Lummis.
Molecular Membrane Biology (2002)
The 5-HT3 receptor--the relationship between structure and function.
Nicholas M. Barnes;Tim G. Hales;Sarah C.R. Lummis;John A. Peters.
γ-Aminobutyric Acid Receptor Binding in Mammalian Brain: Heterogeneity of Binding Sites
R. W. Olsen;M. O. Bergman;P. C. van Ness;S. C. Lummis.
Molecular Pharmacology (1981)
A. J. Thompson;S. C. R. Lummis.
Current Pharmaceutical Design (2006)
A Cation-π Binding Interaction with a Tyrosine in the Binding Site of the GABAC Receptor
Sarah C.R. Lummis;Darren L. Beene;Neil J. Harrison;Henry A. Lester.
Chemistry & Biology (2005)
Expression of recombinant homo-oligomeric 5-hydroxytryptamine3 receptors provides new insights into their maturation and structure.
Tim Green;Kathrin A. Stauffer;Sarah C.R. Lummis.
Journal of Biological Chemistry (1995)
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