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Takashi Shiina

Takashi Shiina

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
12577
World Ranking
14331
National Ranking
1011

Overview

Takashi Shiina is affiliated with Tokai University in Japan and has contributed extensively to research in immunology, microbiology, medicine, and molecular biology. Their work is primarily centered on immunology and related fields, encompassing significant topics such as T-cell and B-cell immunology, immune cell function and interaction, and immunotherapy and immune responses.

Their research spans various subfields including immunology, molecular biology, epidemiology, radiology, nuclear medicine and imaging, and genetics. Key scientific themes addressed in their publications include:

  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • CRISPR and Genetic Engineering
  • Reproductive System and Pregnancy
  • Monoclonal and Polyclonal Antibodies Research
  • Inflammatory Myopathies and Dermatomyositis

Takashi Shiina has authored multiple papers across a range of journals, including highly specialized and general scientific venues. Frequent publication venues include:

  • HLA
  • Frontiers in Immunology
  • Scientific Reports
  • Frontiers in Genetics
  • Stem Cell Reports

Selected recent publications illustrate the diversity and focus of their research:

  • "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution," 2021, Kent Academic Repository (University of Kent)
  • "Capturing Differential Allele-Level Expression and Genotypes of All Classical HLA Loci and Haplotypes by a New Capture RNA-Seq Method," 2020, Frontiers in Immunology
  • "Human leukocyte antigen super-locus: nexus of genomic supergenes, SNPs, indels, transcripts, and haplotypes," 2022, Human Genome Variation
  • "Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates," 2022, Stem Cell Reports
  • "SNP-Density Crossover Maps of Polymorphic Transposable Elements and HLA Genes Within MHC Class I Haplotype Blocks and Junction," 2021, Frontiers in Genetics

The scientist collaborates regularly with several researchers, with the most frequent coauthors being:

  • Shingo Suzuki
  • Jerzy K. Kulski
  • Yoshie Kametani
  • Atsuko Shigenari
  • Shino Ohshima

Through their publications, Takashi Shiina has contributed to advancing knowledge on immune system genetics, transplantation biology, and genomic analysis methods. Their research outputs encompass a multidisciplinary approach, integrating genetic, molecular, and immunological perspectives.

Best Publications

  • Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

    Ladeana W. Hillier;Webb Miller;Ewan Birney;Wesley Warren

  • Complete sequence and gene map of a human major histocompatibility complex

    S Beck;D Geraghty;H Inoko;L Rowen

  • The HLA genomic loci map: expression, interaction, diversity and disease

    Takashi Shiina;Kazuyoshi Hosomichi;Hidetoshi Inoko;Jerzy K Kulski;Jerzy K Kulski

  • Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts

    Yuji Shiba;Toshihito Gomibuchi;Tatsuichiro Seto;Yuko Wada

  • The amphioxus genome illuminates vertebrate origins and cephalochordate biology

    Linda Z. Holland;Ricard Albalat;Kaoru Azumi;Èlia Benito-Gutiérrez

  • Chloroplast-mediated activation of plant immune signalling in Arabidopsis.

    Hironari Nomura;Teiko Komori;Shuhei Uemura;Yui Kanda

  • Direct Comparison of Autologous and Allogeneic Transplantation of iPSC-Derived Neural Cells in the Brain of a Nonhuman Primate

    Asuka Morizane;Daisuke Doi;Tetsuhiro Kikuchi;Keisuke Okita

  • Structural dynamics of cereal mitochondrial genomes as revealed by complete nucleotide sequencing of the wheat mitochondrial genome

    Yasunari Ogihara;Yukiko Yamazaki;Koji Murai;Akira Kanno

  • MHC matching improves engraftment of iPSC-derived neurons in non-human primates.

    Asuka Morizane;Tetsuhiro Kikuchi;Takuya Hayashi;Hiroshi Mizuma

  • Structural features of a wheat plastome as revealed by complete sequencing of chloroplast DNA.

    Y. Ogihara;K. Isono;T. Kojima;A. Endo

  • Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction

    Naoki Okumura;Yuji Sakamoto;Keita Fujii;Junji Kitano

  • Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models.

    Sunao Sugita;Yuko Iwasaki;Kenichi Makabe;Hiroyuki Kamao

  • The impact of next-generation sequencing technologies on HLA research.

    Kazuyoshi Hosomichi;Takashi Shiina;Atsushi Tajima;Ituro Inoue

  • α1,3-Fucoslytransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX

    Mika Kaneko;Mika Kaneko;Takashi Kudo;Hiroko Iwasaki;Yuzuru Ikehara

  • Super high resolution for single molecule‐sequence‐based typing of classical HLA loci at the 8‐digit level using next generation sequencers

    T Shiina;S Suzuki;Y Ozaki;H Taira

  • The genomic sequence and analysis of the swine major histocompatibility complex

    C. Renard;E. Hart;H. Sehra;H. Beasley

  • A Scalable Open-Source Pipeline for Large-Scale Root Phenotyping of Arabidopsis

    Radka Slovak;Christian Göschl;Xiaoxue Su;Koji Shimotani

  • MIC and other NKG2D ligands: from none to too many

    Seiamak Bahram;Hidetoshi Inoko;Takashi Shiina;Mirjana Radosavljevic

  • Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence

    Tatsuya Anzai;Takashi Shiina;Natsuki Kimura;Kazuyo Yanagiya

  • Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates

    Takuji Kawamura;Shigeru Miyagawa;Satsuki Fukushima;Akira Maeda

Frequent Co-Authors

Jerzy K. Kulski
Jerzy K. Kulski University of Western Australia
Hidetoshi Inoko
Hidetoshi Inoko Tokai University
Antoine Blancher
Antoine Blancher Paul Sabatier University
Masao Ota
Masao Ota Shinshu University
Steven G.E. Marsh
Steven G.E. Marsh University College London
Hisashi Yamanaka
Hisashi Yamanaka International University of Health and Welfare
Ryuji Suzuki
Ryuji Suzuki National Institutes of Health
Yasuo Morishima
Yasuo Morishima Aichi Medical University
Ronald E. Bontrop
Ronald E. Bontrop Utrecht University
Ichizo Nishino
Ichizo Nishino Tokyo Medical University

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