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Immunology

D-Index
63
Citations
15423
World Ranking
3004
National Ranking
114

Overview

Peter Heeringa is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily focuses on medicine, with significant contributions to immunology and microbiology. They have published extensively within several subfields, including immunology, pulmonary and respiratory medicine, immunology and allergy, rheumatology, and molecular biology.

The scientist's work covers a range of topics, with a primary focus on vasculitis and related conditions. Other main topics of research include cell adhesion molecules, otitis media and relapsing polychondritis, atherosclerosis and cardiovascular diseases, coagulation and related mechanisms, neutrophil and oxidative mechanisms, and cellular mechanics and interactions.

Peter Heeringa has collaborated frequently with several coauthors. Notable collaborators include William F. Jiemy, Elisabeth Brouwer, Kornelis S. M. van der Geest, Wayel H. Abdulahad, and Maria Sandovici.

Their recent papers include the following:

  • Distinct macrophage phenotypes skewed by local granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) are associated with tissue destruction and intimal hyperplasia in giant cell arteritis, 2020, Clinical & Translational Immunology
  • B Cell Activation and Escape of Tolerance Checkpoints: Recent Insights from Studying Autoreactive B Cells, 2021, Cells
  • A Distinct Macrophage Subset Mediating Tissue Destruction and Neovascularization in Giant Cell Arteritis: Implication of the YKL-40/Interleukin-13 Receptor α2 Axis, 2021, Arthritis & Rheumatology
  • Metabolic features and glucocorticoid-induced comorbidities in patients with giant cell arteritis and polymyalgia rheumatica in a Dutch and Danish cohort, 2023, RMD Open
  • Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing, 2022, The Journal of Experimental Medicine

Peter Heeringa frequently publishes in several academic venues. These include:

  • Annals of the Rheumatic Diseases
  • Lara D. Veeken
  • UNC Libraries
  • Zenodo (CERN European Organization for Nuclear Research)
  • Journal of Autoimmunity

Best Publications

  • Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice

    Hong Xiao;Peter Heeringa;Peiqi Hu;Zhi Liu

  • Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies

    Hong Xiao;Adrian Schreiber;Peter Heeringa;Ronald J. Falk

  • Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease

    Betty S. van der Veen;Menno P. J. de Winther;Peter Heeringa

  • Protective role of endothelial nitric oxide synthase

    Ester W J A Albrecht;Coen A Stegeman;Peter Heeringa;Robert Henning

  • Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression.

    Esther Lutgens;Marion Gijbels;Marjan Smook;Peter Heeringa

  • The Role of Neutrophils in the Induction of Glomerulonephritis by Anti-Myeloperoxidase Antibodies

    Hong Xiao;Peter Heeringa;Zhi Liu;Dennis Huugen

  • Complement Factor C5a Mediates Renal Ischemia-Reperfusion Injury Independent from Neutrophils

    Bart de Vries;Jörg Köhl;Wouter K. G. Leclercq;Tim G. A. M. Wolfs

  • High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice

    Roel A. van der Heijden;Fareeba Sheedfar;Martine C. Morrison;Pascal P. H. Hommelberg

  • Epitope specificity determines pathogenicity and detectability in ANCA-associated vasculitis

    Aleeza J. Roth;Joshua D. Ooi;Jacob J. Hess;Mirjan M. Van Timmeren

  • Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice

    D. Huugen;A. van Esch;H. Xiao;C.-J. Peutz-Kootstra

  • Coexistence of anti-glomerular basement membrane antibodies and myeloperoxidase-ANCAs in crescentic glomerulonephritis.

    Abraham Rutgers;Marjan Slot;Pieter van Paassen;Peter van Breda Vriesman

  • Mechanisms of Disease: pathogenesis and treatment of ANCA-associated vasculitides

    Cees G M Kallenberg;Peter Heeringa;Coen A Stegeman

  • Activation of granulocytes by anti-neutrophil cytoplasmic antibodies (ANCA): a Fc gamma RII-dependent process.

    A. H. L. Mulder;P. Heeringa;E. Brouwer;P. C. Limburg

  • Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha.

    Dennis Huugen;Hong Xiao;Anita van Esch;Ronald J. Falk

  • Complement Activation Is Involved in Renal Damage in Human Antineutrophil Cytoplasmic Autoantibody Associated Pauci-Immune Vasculitis

    Guang-qun Xing;Min Chen;Gang Liu;Peter Heeringa

  • Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR−/− Mice

    Marcella van Leeuwen;Marion J. J. Gijbels;Adriaan Duijvestijn;Marjan Smook

  • Neutrophil activation in vitro and in vivo in Wegener's granulomatosis

    Elisabeth Brouwer;Minke G. Huitema;A.H. Leontine Mulder;Peter Heeringa

  • Inhibition of complement factor C5 protects against renal ischemia-reperfusion injury: inhibition of late apoptosis and inflammation.

    Bart de Vries;Robert A. Matthijsen;Tim G. A. M. Wolfs;Annemarie A. J. H. M. van Bijnen

  • Myeloperoxidase attracts neutrophils by physical forces

    Anna Klinke;Claudia Nussbaum;Lukas Kubala;Kai Friedrichs

  • High Prevalence of Autoantibodies to hLAMP-2 in Anti–Neutrophil Cytoplasmic Antibody–Associated Vasculitis

    Renate Kain;Henko Tadema;Eoin F. McKinney;Alexandra Benharkou

Frequent Co-Authors

Coen A. Stegeman
Coen A. Stegeman University Medical Center Groningen
Elisabeth Brouwer
Elisabeth Brouwer University Medical Center Groningen
Cees G. M. Kallenberg
Cees G. M. Kallenberg University of Groningen
Grietje Molema
Grietje Molema University Medical Center Groningen
Jan Willem Cohen Tervaert
Jan Willem Cohen Tervaert University of Alberta
Cees G. M. Kallenberg
Cees G. M. Kallenberg University of Groningen
Robert Kleemann
Robert Kleemann Netherlands Organisation for Applied Scientific Research
Harry van Goor
Harry van Goor Radboud University
J. Charles Jennette
J. Charles Jennette University of North Carolina at Chapel Hill
Pieter C. Limburg
Pieter C. Limburg University of Groningen

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