D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 14,230 175 World Ranking 7380 National Ranking 175

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Internal medicine
  • Cancer

Her primary scientific interests are in Angiogenesis, Endothelial stem cell, Immunology, Cancer research and Biochemistry. Her work deals with themes such as Cancer, Retinal, Growth factor and Fibroblast growth factor, which intersect with Angiogenesis. Her Endothelial stem cell research is multidisciplinary, incorporating elements of Liposome, Drug delivery and Cell biology.

Her primary area of study in Immunology is in the field of Inflammation. The various areas that Grietje Molema examines in her Cancer research study include Immunotherapy, Antibody, Histone H3 deacetylation and Trichostatin A. Grietje Molema studied Biochemistry and In vivo that intersect with Cancer cell, Drug carrier and Targeted drug delivery.

Her most cited work include:

  • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle (855 citations)
  • Angiogenesis: Potentials for Pharmacologic Intervention in the Treatment of Cancer, Cardiovascular Diseases, and Chronic Inflammation (766 citations)
  • Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature (506 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Endothelial stem cell, Angiogenesis, Immunology, Pathology and Cancer research. Her study in Endothelial stem cell is interdisciplinary in nature, drawing from both Liposome, Cell adhesion molecule, Cell biology, Endothelium and In vivo. Her In vivo study integrates concerns from other disciplines, such as Targeted drug delivery and Biochemistry.

The concepts of her Angiogenesis study are interwoven with issues in Vascular endothelial growth factor A, Vascular endothelial growth factor, Cancer and Growth factor. Grietje Molema frequently studies issues relating to Internal medicine and Immunology. Her research in Immunotherapy tackles topics such as Antigen which are related to areas like Antibody.

She most often published in these fields:

  • Endothelial stem cell (20.33%)
  • Angiogenesis (19.34%)
  • Immunology (19.02%)

What were the highlights of her more recent work (between 2012-2021)?

  • Endothelium (16.39%)
  • Sepsis (6.23%)
  • Immunology (19.02%)

In recent papers she was focusing on the following fields of study:

Endothelium, Sepsis, Immunology, Internal medicine and Cell biology are her primary areas of study. Her studies deal with areas such as Inflammation, Molecular biology, VCAM-1 and Small interfering RNA as well as Endothelium. Her Molecular biology study incorporates themes from Cancer research, Downregulation and upregulation, Transfection and In vivo.

Her Immunology research includes elements of Endothelial stem cell, Receptor, Chemotaxis, Angiopoietin receptor and Shock. Systemic inflammation and Angiogenesis are the subjects of her Internal medicine studies. Her Cell biology research incorporates themes from In vitro and Cell sorting.

Between 2012 and 2021, her most popular works were:

  • A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity (53 citations)
  • Interactions between Blood-Borne Streptococcus pneumoniae and the Blood-Brain Barrier Preceding Meningitis (50 citations)
  • Anti-VCAM-1 and anti-E-selectin SAINT-O-Somes for selective delivery of siRNA into inflammation-activated primary endothelial cells (40 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Cancer

Grietje Molema focuses on Endothelium, Sepsis, Endothelial stem cell, Pathology and Immunology. Her Endothelium course of study focuses on Small interfering RNA and Molecular biology, Cancer research, E-selectin and Cell adhesion molecule. Her research in Cancer research focuses on subjects like Drug delivery, which are connected to RNA interference, Vascular Cell Adhesion Protein 1 and Pharmacology.

Her research integrates issues of Acute kidney injury, Cardiopulmonary bypass, Endothelial activation and Cell biology in her study of Sepsis. Her Endothelial stem cell research integrates issues from Blood–brain barrier, Microbiology, Receptor, Vascular remodelling in the embryo and Gene. She focuses mostly in the field of Immunology, narrowing it down to topics relating to Signal transduction and, in certain cases, Platelet membrane glycoprotein, Proinflammatory cytokine and RIG-I.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

Raymond M. Schiffelers;Aslam Ansari;Jun Xu;Qin Zhou.
Nucleic Acids Research (2004)

1122 Citations

Angiogenesis: Potentials for Pharmacologic Intervention in the Treatment of Cancer, Cardiovascular Diseases, and Chronic Inflammation

Arjan W. Griffioen;Grietje Molema.
Pharmacological Reviews (2000)

1070 Citations

Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature

Xianming Huang;Grietje Molema;Grietje Molema;Steven King;Linda Watkins.
Science (1997)

667 Citations

RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature

Kai Temming;Raymond M. Schiffelers;Grietje Molema;Robbert J. Kok.
Drug Resistance Updates (2005)

537 Citations

Antiviral activities of lactoferrin

B.W.A van der Strate;L Beljaars;G Molema;M.C Harmsen.
Antiviral Research (2001)

513 Citations

Endothelium in vitro: a review of human vascular endothelial cell lines for blood vessel-related research.

Diane Bouïs;Geke A.P. Hospers;Coby Meijer;Grietje Molema.
Angiogenesis (2001)

427 Citations

Potential cellular and molecular causes of hypertrophic scar formation

Willem M. van der Veer;Monica C.T. Bloemen;Magda M.W. Ulrich;Grietje Molema.
Burns (2009)

398 Citations

Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin

Raymond M Schiffelers;Gerben A Koning;Timo L M ten Hagen;Marcel H A M Fens.
Journal of Controlled Release (2003)

389 Citations

A liposomal system for contrast-enhanced magnetic resonance imaging of molecular targets.

Willem J. M. Mulder;Gustav J. Strijkers;Arjan W. Griffioen;Louis Van Bloois.
Bioconjugate Chemistry (2004)

292 Citations

In Vivo Characteristics of Cationic Liposomes as Delivery Vectors for Gene Therapy

Sandrine A. L. Audouy;Lou F. M. H. de Leij;Dick Hoekstra;Grietje Molema.
Pharmaceutical Research (2002)

237 Citations

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