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Medicine

D-Index
97
Citations
31411
World Ranking
9365
National Ranking
363

Overview

Arjan W. Griffioen is affiliated with the University of Amsterdam in the Netherlands and has a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work extensively covers molecular biology and immunology, with significant publications in oncology, cancer research, and obstetrics and gynecology.

Their research topics concentrate on angiogenesis and VEGF in cancer, immunotherapy and immune responses, cell adhesion molecules research, as well as endometriosis research and treatment. Additionally, their work addresses uterine myomas and treatments, cancer hypoxia and metabolism, and inflammatory biomarkers in disease prognosis.

Frequently collaborating co-authors include Elisabeth J. M. Huijbers, Judy R. van Beijnum, Patrycja Nowak-Sliwinska, Karlijn van Loon, and Siamack Sabrkhany.

Griffioen has published extensively in several scientific journals. The main publication venues for their work include:

  • Angiogenesis
  • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • Cancers
  • APOPTOSIS
  • International Journal of Molecular Sciences

Some of their recent papers are as follows:

  • Anti-angiogenic agents - overcoming tumour endothelial cell anergy and improving immunotherapy outcomes, 2021, Nature Reviews Clinical Oncology
  • Pathological angiogenesis: mechanisms and therapeutic strategies, 2023, Angiogenesis
  • COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects, 2021, Angiogenesis
  • Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition, 2020, Cell
  • Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumors, 2020, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Best Publications

  • Angiogenesis: Potentials for Pharmacologic Intervention in the Treatment of Cancer, Cardiovascular Diseases, and Chronic Inflammation

    Arjan W. Griffioen;Grietje Molema

  • Tumour vascularization: sprouting angiogenesis and beyond

    Femke Hillen;Arjan W. Griffioen

  • Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis

    Patrick W.B. Derksen;Xiaoling Liu;Francis Saridin;Hanneke van der Gulden

  • Lipid-based nanoparticles for contrast-enhanced MRI and molecular imaging.

    Willem J. M. Mulder;Gustav J. Strijkers;Geralda A. F. van Tilborg;Arjan W. Griffioen

  • Convergence and Amplification of Toll-Like Receptor (TLR) and Receptor for Advanced Glycation End Products (RAGE) Signaling Pathways via High Mobility Group B1 (HMGB1)

    Judy R van Beijnum;Wim A Buurman;Arjan W Griffioen

  • Consensus guidelines for the use and interpretation of angiogenesis assays

    Patrycja Nowak-Sliwinska;Kari Alitalo;Elizabeth Allen;Andrey Anisimov

  • Quantum dots with a paramagnetic coating as a bimodal molecular imaging probe

    Willem J. M. Mulder;Rolf Koole;Ricardo J. Brandwijk;Gert Storm

  • Anti-angiogenesis for cancer revisited: Is there a role for combinations with immunotherapy?

    Rakesh R. Ramjiawan;Arjan W. Griffioen;Dan G. Duda

  • Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy

    Victor L. J. L. Thijssen;Ruben Postel;Ricardo J. M. G. E. Brandwijk;Ruud P. M. Dings

  • Monocyte/macrophage infiltration in tumors : modulators of angiogenesis

    Anita E. M. Dirkx;Mirjam G. A. oude Egbrink;John Wagstaff;Arjan W. Griffioen

  • Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth.

    Yumi Yokoyama;Mohanraj Dhanabal;Arjan W. Griffioen;Vikas P. Sukhatme

  • Antiangiogenesis therapy for endometriosis

    Annemiek W Nap;Arjan W Griffioen;Gerard A J Dunselman;Jessica C A Bouma-Ter Steege

  • Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance

    Kristy J. Gotink;Henk J. Broxterman;Mariette Labots;Richard R. de Haas

  • MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle

    Willem J. M. Mulder;Gustav J. Strijkers;Jo W. Habets;Egbert J. W. Bleeker

  • Scheduling of Radiation with Angiogenesis Inhibitors Anginex and Avastin Improves Therapeutic Outcome via Vessel Normalization

    Ruud P.M. Dings;Melissa Loren;Hanke Heun;Elizabeth McNiel

  • Endothelial Intercellular Adhesion Molecule-1 Expression Is Suppressed in Human Malignancies: The Role of Angiogenic Factors

    Arjan W. Griffioen;Cora A. Damen;Stefano Martinotti;Geert H. Blijham

  • Tumor angiogenesis is accompanied by a decreased inflammatory response of tumor-associated endothelium

    Arjan W. Griffioen;Cora A. Damen;Geert H. Blijham;Gerard Groenewegen

  • Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression.

    Anita E M Dirkx;Mirjam G A Oude Egbrink;Marijke J E Kuijpers;Sandra T van der Niet

  • A liposomal system for contrast-enhanced magnetic resonance imaging of molecular targets.

    Willem J. M. Mulder;Gustav J. Strijkers;Arjan W. Griffioen;Louis Van Bloois

  • Galectin expression in cancer diagnosis and prognosis: a systematic review

    Victor L. Thijssen;Roy Heusschen;Jo Caers;Arjan W. Griffioen

Frequent Co-Authors

Henk M.W. Verheul
Henk M.W. Verheul Radboud University
Paul J. Dyson
Paul J. Dyson École Polytechnique Fédérale de Lausanne
Gert Storm
Gert Storm Utrecht University
Manon van Engeland
Manon van Engeland Maastricht University
Joseph Martial
Joseph Martial University of Liège
Zahi A. Fayad
Zahi A. Fayad Icahn School of Medicine at Mount Sinai
Godefridus J. Peters
Godefridus J. Peters Gdańsk Medical University
Roberto Pili
Roberto Pili University at Buffalo, State University of New York
Agnès Noël
Agnès Noël University of Liège
Grietje Molema
Grietje Molema University Medical Center Groningen

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