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Medicine

D-Index
102
Citations
31788
World Ranking
7756
National Ranking
4042

Research.com Recognitions

  • 2019 - Fellow of the Indian National Academy of Engineering (INAE)
  • 2019 - Fellow, National Academy of Inventors

Overview

Samuel A. Wickline is affiliated with the University of South Florida in the United States. Their research contributions span multiple areas within Medicine and Biochemistry, Genetics and Molecular Biology, focusing substantially on Molecular Biology, Immunology, Pulmonary and Respiratory Medicine, Pathology and Forensic Medicine, and Surgery.

The scientist's recent publications reflect diverse biomedical topics and experimental approaches. Significant papers include:

  • Dual role of endothelial Myct1 in tumor angiogenesis and tumor immunity, 2021, Science Translational Medicine
  • Self-assembled miRNA-switch nanoparticles target denuded regions and prevent restenosis, 2021, Molecular Therapy
  • Amelioration of Posttraumatic Osteoarthritis in Mice Using Intraarticular Silencing of Periostin via Nanoparticle-Based Small Interfering RNA, 2021, Arthritis & Rheumatology
  • Targeted inhibition of thrombin attenuates murine neonatal necrotizing enterocolitis, 2020, Proceedings of the National Academy of Sciences
  • Induction of WNT16 via Peptide-mRNA Nanoparticle-Based Delivery Maintains Cartilage Homeostasis, 2020, Pharmaceutics

The scientist collaborates frequently with several co-authors, including:

  • Hua Pan
  • Christine T. N. Pham
  • Antonina Akk
  • Ian Vargas
  • Qingyu Zhou

Wickline's publications often appear in journals such as Circulation, International Journal of Molecular Sciences, Nanomaterials, Journal of Pharmacology and Experimental Therapeutics, and European Heart Journal. The research topics covered in these works include:

  • Immune cells in cancer
  • RNA Interference and Gene Delivery
  • Chemotherapy-induced organ toxicity mitigation
  • Aortic aneurysm repair treatments
  • Acute Kidney Injury Research
  • Osteoarthritis Treatment and Mechanisms
  • Immunotherapy and Immune Responses

Their research blends experimental therapeutics and molecular mechanisms, often focusing on novel nanoparticle-based delivery systems for gene silencing and molecular targeting.

Acknowledgments of their work include being elected as a Fellow of the National Academy of Inventors and Fellow of the Indian National Academy of Engineering (INAE) in 2019.

Best Publications

  • Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis

    Joshua L. Hood;Roman Susana San;Samuel A. Wickline

  • Molecular Imaging of Angiogenesis in Early-Stage Atherosclerosis With αvβ3-Integrin–Targeted Nanoparticles

    Patrick M. Winter;Anne M. Morawski;Shelton D. Caruthers;Ralph W. Fuhrhop

  • Novel MRI Contrast Agent for Molecular Imaging of Fibrin Implications for Detecting Vulnerable Plaques

    Sebastian Flacke;Stefan Fischer;Michael J. Scott;Ralph J. Fuhrhop

  • Nanotechnological applications in medicine

    Shelton D Caruthers;Shelton D Caruthers;Samuel A Wickline;Gregory M Lanza

  • Molecular Imaging of Angiogenesis in Nascent Vx-2 Rabbit Tumors Using a Novel ανβ3-targeted Nanoparticle and 1.5 Tesla Magnetic Resonance Imaging

    Patrick M. Winter;Shelton D. Caruthers;Andrea Kassner;Thomas D. Harris

  • A Novel Site-Targeted Ultrasonic Contrast Agent With Broad Biomedical Application

    Gregory M. Lanza;Kirk D. Wallace;Michael J. Scott;William P. Cacheris

  • Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme.

    Igor Halpert;Ulrike I. Sires;Jill D. Roby;Susan Potter-Perigo

  • Endothelial ανβ3 Integrin-Targeted Fumagillin Nanoparticles Inhibit Angiogenesis in Atherosclerosis

    Patrick M. Winter;Anne M. Neubauer;Shelton D. Caruthers;Thomas D. Harris

  • Targeted Antiproliferative Drug Delivery to Vascular Smooth Muscle Cells With a Magnetic Resonance Imaging Nanoparticle Contrast Agent Implications for Rational Therapy of Restenosis

    Gregory M. Lanza;Xin Yu;Patrick M. Winter;Dana R. Abendschein

  • Practical Value of Cardiac Magnetic Resonance Imaging for Clinical Quantification of Aortic Valve Stenosis Comparison With Echocardiography

    Shelton D. Caruthers;Shiow Jiuan Lin;Peggy Brown;Mary P. Watkins

  • Novel real-time R-wave detection algorithm based on the vectorcardiogram for accurate gated magnetic resonance acquisitions.

    Stefan E. Fischer;Samuel A. Wickline;Christine H. Lorenz

  • 19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons

    Kathryn C. Partlow;Junjie Chen;Jason A. Brant;Anne M. Neubauer

  • Magnetic resonance contrast enhancement of neovasculature with αvβ3‐targeted nanoparticles

    Stasia A. Anderson;Randall K. Rader;William F. Westlin;Christopher Null

  • Targeted nanoparticles for quantitative imaging of sparse molecular epitopes with MRI

    Anne M. Morawski;Patrick M. Winter;Kathryn C. Crowder;Shelton D. Caruthers;Shelton D. Caruthers

  • Molecular MR imaging of melanoma angiogenesis with alphanubeta3-targeted paramagnetic nanoparticles

    Anne H. Schmieder;Patrick M. Winter;Shelton D. Caruthers;Shelton D. Caruthers;Thomas D. Harris

  • Paracrine induction of endothelium by tumor exosomes.

    Joshua L Hood;Hua Pan;Gregory M Lanza;Samuel A Wickline

  • Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth.

    Neeleesh R Soman;Steven L Baldwin;Grace Hu;Jon N Marsh

  • Targeted contrast agents for magnetic resonance imaging and ultrasound.

    Anne M Morawski;Gregory A Lanza;Samuel A Wickline

  • High-resolution MRI characterization of human thrombus using a novel fibrin-targeted paramagnetic nanoparticle contrast agent.

    Xin Yu;Sheng Kwei Song;Junjie Chen;Michael J. Scott

  • Remodeling of cardiac fiber structure after infarction in rats quantified with diffusion tensor MRI

    Junjie Chen;Sheng Kwei Song;Wei Liu;Mark McLean

Frequent Co-Authors

Dipanjan Pan
Dipanjan Pan Pennsylvania State University
Paul H. Schlesinger
Paul H. Schlesinger Washington University in St. Louis
Lihong V. Wang
Lihong V. Wang California Institute of Technology
David G. Mutch
David G. Mutch Washington University in St. Louis
Manojit Pramanik
Manojit Pramanik Iowa State University
Burton E. Sobel
Burton E. Sobel Washington University in St. Louis
John Allen
John Allen Coventry University
John F. McCarthy
John F. McCarthy University of Tennessee at Knoxville
Douglas M. Tollefsen
Douglas M. Tollefsen Washington University in St. Louis
Rashid Bashir
Rashid Bashir University of Illinois at Urbana-Champaign

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