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Biology and Biochemistry

D-Index
69
Citations
20747
World Ranking
7290
National Ranking
3340

Overview

Paul H. Schlesinger is affiliated with Washington University in St. Louis in the United States. Their research spans multiple fields, including Medicine and Biochemistry, Genetics and Molecular Biology, with specific subfields focusing on Rheumatology, Oncology, Orthopedics and Sports Medicine, Endocrinology, Diabetes and Metabolism, and Molecular Biology.

The main topics explored in their work include:

  • Alkaline Phosphatase Research Studies
  • Bone health and treatments
  • Heterotopic Ossification and Related Conditions
  • Parathyroid Disorders and Treatments
  • Bone health and osteoporosis research
  • Bone and Dental Protein Studies
  • Trypanosoma species research and implications

Schlesinger's frequent coauthors reflect a collaborative approach to research, and they have worked extensively with:

  • Harry C. Blair
  • Irina L. Tourkova
  • Quitterie C. Larrouture
  • Deborah J. Nelson
  • Vladimir Riazanski

Their recent papers illustrate a consistent focus on biological mineral transport, bone cell function, and protein biochemistry. These include:

  • "Phylogeny and chemistry of biological mineral transport," 2020, published in Bone
  • "Growth and mineralization of osteoblasts from mesenchymal stem cells on microporous membranes: Epithelial-like growth with transmembrane resistance and pH gradient," 2021, published in Biochemical and Biophysical Research Communications
  • "Age-related decline in bone mineral transport and bone matrix proteins in osteoblasts from stromal stem cells," 2023, published in American Journal of Physiology-Cell Physiology
  • "Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration," 2022, published in Journal of Biological Chemistry
  • "Epithelial-like transport of mineral distinguishes bone formation from other connective tissues," 2023, published in Journal of Cellular Biochemistry

Paul H. Schlesinger's work has appeared predominantly in venues such as:

  • American Journal of Physiology-Cell Physiology
  • Journal of Cellular Biochemistry
  • Biochemical and Biophysical Research Communications
  • Bone
  • Journal of Biological Chemistry

Best Publications

  • Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase

    Sheila Sturgill-Koszycki;Paul H. Schlesinger;Prasanta Chakraborty;Pryce L. Haddix

  • Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

    S. J. Korsmeyer;M. C. Wei;M. C. Wei;M. Saito;S. Weiler

  • Evidence for receptor-mediated binding of glycoproteins, glycoconjugates, and lysosomal glycosidases by alveolar macrophages.

    P. D. Stahl;J. S. Rodman;M. J. Miller;Paul Schlesinger

  • Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance

    Donald J. Krogstad;Ilya Y. Gluzman;Dennis E. Kyle;Ayoade M. J. Oduola

  • Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2

    Paul H. Schlesinger;Atan Gross;Xiao Ming Yin;Kazuhito Yamamoto

  • Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recycling

    Philip Stahl;Paul H. Schlesinger;Elaine Sigardson;Jane S. Rodman

  • BAX-dependent transport of cytochrome c reconstituted in pure liposomes.

    Mitsuyoshi Saito;Stanley J. Korsmeyer;Paul H. Schlesinger

  • Cytokine Activation Leads to Acidification and Increases Maturation of Mycobacterium avium -Containing Phagosomes in Murine Macrophages

    Ulrich E. Schaible;Sheila Sturgill-Koszycki;Paul H. Schlesinger;David G. Russell

  • Triggered recruitment of ESCRT machinery promotes endolysosomal repair

    Michael L. Skowyra;Paul H. Schlesinger;Teresa V. Naismith;Phyllis I. Hanson

  • Osteoblast differentiation and bone matrix formation in vivo and in vitro

    Harry C. Blair;Quitterie C. Larrouture;Yanan Li;Hang Lin

  • Bisphosphonates directly inhibit the bone resorption activity of isolated avian osteoclasts in vitro.

    Aldo Carano;Steven L. Teitelbaum;John D. Konsek;Paul H. Schlesinger

  • Antimalarials increase vesicle pH in Plasmodium falciparum.

    Donald J. Krogstad;Paul Schlesinger;Ilya Y. Gluzman

  • Isolation of the galactose-binding lectin that mediates the in vitro adherence of Entamoeba histolytica.

    W A Petri;R D Smith;P H Schlesinger;C F Murphy

  • Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth.

    Neeleesh R Soman;Steven L Baldwin;Grace Hu;Jon N Marsh

  • Oxysterols are allosteric activators of the oncoprotein Smoothened

    Sigrid Nachtergaele;Laurel K Mydock;Kathiresan Krishnan;Jayan Rammohan

  • Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: Apparent inhibition of receptor recycling

    Christopher Tietze;Paul Schlesinger;Philip Stahl

  • Plasma clearance of glycoproteins with terminal mannose and N-acetylglucosamine by liver non-parenchymal cells. Studies with beta-glucuronidase, N-acetyl-beta-D-glucosaminidase, ribonuclease B and agalacto-orosomucoid.

    P H Schlesinger;T W Doebber;B F Mandell;R White

  • Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells.

    P Rothenberg;L Glaser;P Schlesinger;D Cassel

  • Wolframin Expression Induces Novel Ion Channel Activity in Endoplasmic Reticulum Membranes and Increases Intracellular Calcium

    Abdullah A. Osman;Mitsuyoshi Saito;Carol Makepeace;M. Alan Permutt

  • Characterization of the Osteoclast Ruffled Border Chloride Channel and Its Role in Bone Resorption

    Paul H. Schlesinger;Harry C. Blair;Steven L. Teitelbaum;John C. Edwards

Frequent Co-Authors

Samuel A. Wickline
Samuel A. Wickline University of South Florida
George W. Gokel
George W. Gokel University of Missouri–St. Louis
Harry C. Blair
Harry C. Blair University of Pittsburgh
Philip D. Stahl
Philip D. Stahl Washington University in St. Louis
Daniel S. Ory
Daniel S. Ory Washington University in St. Louis
Nathan A. Baker
Nathan A. Baker Pacific Northwest National Laboratory
Steven L. Teitelbaum
Steven L. Teitelbaum Washington University in St. Louis
Douglas F. Covey
Douglas F. Covey Washington University in St. Louis
Deborah J. Nelson
Deborah J. Nelson University of Chicago
William E. Goldman
William E. Goldman University of North Carolina at Chapel Hill

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